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公开(公告)号:US20060133957A1
公开(公告)日:2006-06-22
申请号:US10759556
申请日:2004-01-16
申请人: Merrill Knapp , Victor Aguero , Jose Joseph , Keith Laderoute , Richard Heydt , Rachel McCloskey
发明人: Merrill Knapp , Victor Aguero , Jose Joseph , Keith Laderoute , Richard Heydt , Rachel McCloskey
IPC分类号: B01L3/00
CPC分类号: B01L3/5021 , B01L3/5027 , B01L2400/0633 , B01L2400/0683 , B01L2400/086 , C12N15/10 , C12N15/1003 , G01N1/286
摘要: A device and method for use with a centrifuge for fragmenting solute or particulate material contained in a liquid sample are disclosed. The device includes a substrate adapted to be supported within a centrifuge tube, and providing a microchannel defining a plurality of shear regions. Material contained in a liquid sample applied to the device, with such supported in a centrifuge tube within a centrifuge, is fragmented by shearing as the sample is forced successively through the plurality of shear regions in the microchannel, when the selected centrifugal force applied to the tube.
摘要翻译: 公开了一种与离心机一起使用以将包含在液体样品中的溶质或微粒材料碎裂的装置和方法。 该装置包括适于被支撑在离心管内的衬底,以及提供限定多个剪切区域的微通道。 通过剪切使应用于装置的液体样品中所含有的液体样品中的物质通过剪切而被分段,当样品被强制依次通过微通道中的多个剪切区域时,当选择的离心力施加到 管。