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公开(公告)号:US07888356B2
公开(公告)日:2011-02-15
申请号:US11971693
申请日:2008-01-09
申请人: Ving Lee , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Tsutomu Akama , Yong-Kang Zhang , Rajesjwar Singh , Vittorio A. Sauro , Chetan Pandit , Zhuoyi Su , Zhixiang Yang
发明人: Ving Lee , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Tsutomu Akama , Yong-Kang Zhang , Rajesjwar Singh , Vittorio A. Sauro , Chetan Pandit , Zhuoyi Su , Zhixiang Yang
IPC分类号: A61K31/47 , A61P31/04 , A61P31/10 , C07D487/04 , C07D215/02 , C07D239/70 , C07D253/08
CPC分类号: C07F5/025
摘要: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
摘要翻译: 公开了包含硼酸络合物的抗生素的结构和制备,特别是羟基喹啉,咪唑和吡啶甲酸衍生物,以及这些抗生素的组合物以及使用抗生素和组合物作为杀菌和杀真菌剂的方法以及用于治疗 细菌和真菌引起的疾病。