公开(公告)号：US07741844B2

公开(公告)日：2010-06-22

申请号：US11745043

申请日：2007-05-07

申请人： Ileana Hancu ,  Richard Philip Mallozzi

发明人： Ileana Hancu ,  Richard Philip Mallozzi

IPC分类号： G01V3/00 ,  A61B5/05

CPC分类号： G01R33/5601 ,  A61B5/0037 ,  A61B5/055 ,  G01R33/4633 ,  G01R33/543 ,  G01R33/583

摘要： A method and system for imaging using labeled contrast agents and a magnetic resonance imaging (MRI) scanner are provided. The method comprises performing a prescan at a frequency selected to be substantially similar to a frequency of the labeled contrast agent and performing an examination scan at the frequency of the labeled contrast agent substantially immediately after administering the labeled contrast agent to a subject.

摘要翻译： 提供了使用标记的造影剂和磁共振成像（MRI）扫描仪进行成像的方法和系统。 该方法包括以选定的频率基本上类似于标记的造影剂的频率执行预扫描，并且在对受试者施用标记的造影剂之后基本上立即以标记的造影剂的频率执行检查扫描。

公开(公告)号：US07725157B2

公开(公告)日：2010-05-25

申请号：US11383608

申请日：2006-05-16

申请人： Charles Lucian Dumoulin ,  Richard Philip Mallozzi ,  Robert David Darrow ,  Harvey Ellis Cline ,  Renee Ann Guhde

发明人： Charles Lucian Dumoulin ,  Richard Philip Mallozzi ,  Robert David Darrow ,  Harvey Ellis Cline ,  Renee Ann Guhde

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/06 ,  A61B5/743 ,  A61B6/503 ,  A61B6/504 ,  A61B8/0891 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2090/364 ,  A61B2090/374 ,  G01R33/287

摘要： An imaging and interventional system and methods are provided. The system comprises an imaging device for acquiring volumetric image data for an anatomical region of interest, a catheter for acquiring electrophysiological (EP) measurements of the anatomical region of interest, the catheter having at least one tracking coil for detecting signals indicative of a position of the catheter, and, a processor coupled to the catheter for receiving the EP measurements and signals indicative of the position of the catheter. The position of the catheter and EP measurements are combined and superimposed on a resultant image. The method comprises acquiring volumetric image data for an anatomical region of interest, acquiring position data for a catheter inserted in the region of interest, obtaining electrophysiological (EP) measurements for the region of interest and combining the image data, position data and EP measurements into a resultant image for use in the interventional procedure.

摘要翻译： 提供了成像和介入系统和方法。 该系统包括用于获取感兴趣解剖区域的体积图像数据的成像装置，用于获取感兴趣解剖区域的电生理学（EP）测量值的导管，所述导管具有至少一个跟踪线圈，用于检测指示位置的信号 导管，以及耦合到导管的处理器，用于接收EP测量值和指示导管位置的信号。 将导管的位置和EP测量结合并叠加在合成的图像上。 该方法包括获取感兴趣的解剖区域的体积图像数据，获取插入在感兴趣区域中的导管的位置数据，获得感兴趣区域的电生理（EP）测量值，并将图像数据，位置数据和EP测量结合到 用于介入程序的结果图像。

公开(公告)号：US20090275821A1

公开(公告)日：2009-11-05

申请号：US12114888

申请日：2008-05-05

申请人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

发明人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

IPC分类号： A61B5/055

CPC分类号： G01R33/565 ,  G01R33/4804 ,  G01R33/4808 ,  G01R33/5602 ,  G01R33/56509 ,  G01R33/56563

摘要： An apparatus and method for correcting magnetic resonance temperature measurements is disclosed. In one aspect, the method identifies monitoring regions of interest outside a therapeutic region of interest. Next, a pulse sequence sensitive to changes in T1 and proton density is used to measure the temperature changes in these regions. Next, the PRFS is measured in these same regions. The PRFS in these regions will be caused both by the desired shift from temperature change, and the undesired shift from background magnetic field changes. Using the measured temperature changes from the T1-method, the component of the PRFS due to actual temperature changes is subtracted from the PRFS method, leaving only the component caused by the unwanted magnetic field changes. This analysis is performed separately for each region. At the end of this step, one has measured the change in background magnetic field within each region.

摘要翻译： 公开了用于校正磁共振温度测量的装置和方法。 在一个方面，该方法识别感兴趣的治疗区域之外的感兴趣的感兴趣区域。 接下来，使用对T1和质子密度变化敏感的脉冲序列来测量这些区域中的温度变化。 接下来，在这些相同的区域中测量PRFS。 这些区域中的PRFS将由温度变化的期望转变和来自背景磁场变化的不希望的偏移引起。 使用T1测量的温度变化，从PRFS方法中减去由于实际温度变化导致的PRFS分量，仅留下由不需要的磁场引起的分量变化。 对每个区域分别进行分析。 在该步骤结束时，测量了每个区域内的背景磁场的变化。

公开(公告)号：US20090184712A1

公开(公告)日：2009-07-23

申请号：US12017006

申请日：2008-01-19

申请人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

发明人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

IPC分类号： G01R33/483 ,  A61B5/055

CPC分类号： G01R33/287 ,  A61B5/055 ,  G01R33/34084 ,  G01R33/3678 ,  G01R33/483

摘要： A system and method for active MR tracking includes a magnetic resonance imaging (MRI) system having a plurality of gradient coils positioned about a bore of a magnet, an RF coil assembly positioned in the bore, and a pulse module. The MRI system also includes a polarization reversal switch controlled by the pulse module to transmit RF signals to the RF coil assembly coupled to the polarization reversal switch and an RF switch controlled by the pulse module to transmit the RF signals to the polarization reversal switch.

摘要翻译： 用于主动MR跟踪的系统和方法包括磁共振成像（MRI）系统，其具有围绕磁体的孔定位的多个梯度线圈，位于孔中的RF线圈组件和脉冲模块。 MRI系统还包括由脉冲模块控制的偏振反转开关，以将RF信号传输到耦合到偏振反转开关的RF线圈组件和由脉冲模块控制的RF开关，以将RF信号传输到偏振反转开关。

公开(公告)号：US20080200973A1

公开(公告)日：2008-08-21

申请号：US11708420

申请日：2007-02-20

申请人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

发明人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

IPC分类号： A61N1/05

CPC分类号： A61N1/046 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/086 ,  G01R33/28

摘要： In accordance with embodiments of the present technique an electrode pad for medical use is provides. The electrode pad comprises a support layer a plurality of electrodes mounted on the support layer and electrically insulated from one another, and a plurality of leads electrically coupled to the electrodes for selectively placing the electrodes at a desired electrical potential.

摘要翻译： 根据本技术的实施例，提供了用于医疗用途的电极垫。 电极焊盘包括支撑层，多个电极安装在支撑层上并彼此电绝缘，以及多个电极，电连接到电极，用于选择性地将电极放置在期望的电位。

公开(公告)号：US06437568B1

公开(公告)日：2002-08-20

申请号：US09676945

申请日：2000-10-02

申请人： William Alan Edelstein ,  Richard Philip Mallozzi ,  Robert Arvin Hedeen ,  Sayed-Amr El-Hamamsy ,  Mark Lloyd Miller ,  Paul Shadforth Thompson ,  Robert Adolph Ackermann ,  Bruce Campbell Amm ,  John Peter Fura ,  Mike James Radziun ,  David Edward Dean ,  Scott Thomas Mansell ,  Dewain Anthony Purgill ,  Robert Michael Vavrek

发明人： William Alan Edelstein ,  Richard Philip Mallozzi ,  Robert Arvin Hedeen ,  Sayed-Amr El-Hamamsy ,  Mark Lloyd Miller ,  Paul Shadforth Thompson ,  Robert Adolph Ackermann ,  Bruce Campbell Amm ,  John Peter Fura ,  Mike James Radziun ,  David Edward Dean ,  Scott Thomas Mansell ,  Dewain Anthony Purgill ,  Robert Michael Vavrek

IPC分类号： G01V300

CPC分类号： G01R33/3854

摘要： A low noise imaging apparatus for producing Magnetic Resonance (MR) images of a subject and for substantially minimizing acoustic noise generated during imaging is provided. The imaging apparatus comprises a magnet assembly, a gradient coil assembly, and a rf coil assembly, wherein at least one of the magnet assembly, the gradient coil assembly and the rf coil assembly are configured to reduce the generation and transmission of acoustic noise.

摘要翻译： 提供了用于产生受试者的磁共振（MR）图像并且用于基本上最小化在成像期间产生的声学噪声的低噪声成像装置。 成像设备包括磁体组件，梯度线圈组件和射频线圈组件，其中磁体组件，梯度线圈组件和射频线圈组件中的至少一个被配置为减少声学噪声的产生和传输。

公开(公告)号：US20070249928A1

公开(公告)日：2007-10-25

申请号：US11590949

申请日：2006-11-01

申请人： Daniel James Blezek ,  Ileana Hancu ,  Michelle Dumoulin ,  Richard Philip Mallozzi

发明人： Daniel James Blezek ,  Ileana Hancu ,  Michelle Dumoulin ,  Richard Philip Mallozzi

IPC分类号： A61B5/05

CPC分类号： G01R33/565 ,  A61B5/0037 ,  G01R33/485 ,  G01R33/5608 ,  G01R33/56509

摘要： The present invention provides a method and system for automatically processing longitudinal magnetic resonance (MR) images comprising obtaining a first MR image, selecting a region of interest within the first MR image, obtaining at least one subsequent MR image, applying a registration relative to the first MR image and the at least one subsequent MR image wherein the region of interest in the at least one subsequent MR image is repositioned analogously to the region of interest in the first MR image. A computer readable program is provided configured to apply a registration relative to a first MR image and an at least one subsequent MR wherein a region of interest in the at least one subsequent MR image is repositioned analogously to a region of interest in the first MR image.

摘要翻译： 本发明提供一种用于自动处理纵向磁共振（MR）图像的方法和系统，包括获得第一MR图像，选择第一MR图像内的感兴趣区域，获得至少一个后续MR图像，相对于 第一MR图像和所述至少一个后续MR图像，其中所述至少一个后续MR图像中的感兴趣区域类似于第一MR图像中的感兴趣区域重新定位。 提供了一种计算机可读程序，其被配置为相对于第一MR图像和至少一个后续MR应用注册，其中所述至少一个后续MR图像中的感兴趣区域类似于第一MR图像中的感兴趣区域重新定位 。

公开(公告)号：US08024025B2

公开(公告)日：2011-09-20

申请号：US12114888

申请日：2008-05-05

申请人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

发明人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

IPC分类号： A61B5/05

CPC分类号： G01R33/565 ,  G01R33/4804 ,  G01R33/4808 ,  G01R33/5602 ,  G01R33/56509 ,  G01R33/56563

摘要： An apparatus and method for correcting magnetic resonance temperature measurements is disclosed. In one aspect, the method identifies monitoring regions of interest outside a therapeutic region of interest. Next, a pulse sequence sensitive to changes in T1 and proton density is used to measure the temperature changes in these regions. Next, the PRFS is measured in these same regions. The PRFS in these regions will be caused both by the desired shift from temperature change, and the undesired shift from background magnetic field changes. Using the measured temperature changes from the T1-method, the component of the PRFS due to actual temperature changes is subtracted from the PRFS method, leaving only the component caused by the unwanted magnetic field changes. This analysis is performed separately for each region. At the end of this step, one has measured the change in background magnetic field within each region.

摘要翻译： 公开了用于校正磁共振温度测量的装置和方法。 在一个方面，该方法识别感兴趣的治疗区域之外的感兴趣的感兴趣区域。 接下来，使用对T1和质子密度变化敏感的脉冲序列来测量这些区域中的温度变化。 接下来，在这些相同的区域中测量PRFS。 这些区域中的PRFS将由温度变化的期望转变和来自背景磁场变化的不希望的偏移引起。 使用T1测量的温度变化，从PRFS方法中减去由于实际温度变化导致的PRFS分量，仅留下由不需要的磁场引起的分量变化。 对每个区域分别进行分析。 在该步骤结束时，测量了每个区域内的背景磁场的变化。

公开(公告)号：US07573267B1

公开(公告)日：2009-08-11

申请号：US12017006

申请日：2008-01-19

申请人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

发明人： Richard Philip Mallozzi ,  Charles Lucian Dumoulin

IPC分类号： G01V3/00

CPC分类号： G01R33/287 ,  A61B5/055 ,  G01R33/34084 ,  G01R33/3678 ,  G01R33/483

摘要： A system and method for active MR tracking includes a magnetic resonance imaging (MRI) system having a plurality of gradient coils positioned about a bore of a magnet, an RF coil assembly positioned in the bore, and a pulse module. The MRI system also includes a polarization reversal switch controlled by the pulse module to transmit RF signals to the RF coil assembly coupled to the polarization reversal switch and an RF switch controlled by the pulse module to transmit the RF signals to the polarization reversal switch.

摘要翻译： 用于主动MR跟踪的系统和方法包括磁共振成像（MRI）系统，其具有围绕磁体的孔定位的多个梯度线圈，位于孔中的RF线圈组件和脉冲模块。 MRI系统还包括由脉冲模块控制的偏振反转开关，以将RF信号传输到耦合到偏振反转开关的RF线圈组件和由脉冲模块控制的RF开关，以将RF信号传输到偏振反转开关。

公开(公告)号：US20080278163A1

公开(公告)日：2008-11-13

申请号：US11745043

申请日：2007-05-07

申请人： ILEANA HANCU ,  RICHARD PHILIP MALLOZZI

发明人： ILEANA HANCU ,  RICHARD PHILIP MALLOZZI

IPC分类号： G01V3/14

CPC分类号： G01R33/5601 ,  A61B5/0037 ,  A61B5/055 ,  G01R33/4633 ,  G01R33/543 ,  G01R33/583

摘要： A method and system for imaging using labeled contrast agents and a magnetic resonance imaging (MRI) scanner are provided. The method comprises performing a prescan at a frequency selected to be substantially similar to a frequency of the labeled contrast agent and performing an examination scan at the frequency of the labeled contrast agent substantially immediately after administering the labeled contrast agent to a subject.

摘要翻译： 提供了使用标记的造影剂和磁共振成像（MRI）扫描仪进行成像的方法和系统。 该方法包括以选定的频率基本上类似于标记的造影剂的频率执行预扫描，并且在对受试者施用标记的造影剂之后基本上立即以标记的造影剂的频率执行检查扫描。