公开(公告)号：US07399645B2

公开(公告)日：2008-07-15

申请号：US11126837

申请日：2005-05-11

申请人： Ricky F. Baggio ,  Alison L. Sparks ,  Rouh-Rong Juo ,  Jaime E. Arenas

发明人： Ricky F. Baggio ,  Alison L. Sparks ,  Rouh-Rong Juo ,  Jaime E. Arenas

IPC分类号： G01N33/547 ,  G01N33/543 ,  G01N33/532 ,  C07K1/10 ,  C07K1/13 ,  C07F5/02

CPC分类号： B82Y30/00 ,  A61K47/54 ,  C07H21/04 ,  G01N33/54353 ,  Y10S530/812

摘要： The invention pertains to bioconjugation systems comprising sterically constrained cis-diols and borates.

摘要翻译： 本发明涉及包含空间受限的顺式二醇和硼酸盐的生物共轭体系。

公开(公告)号：US08852414B2

公开(公告)日：2014-10-07

申请号：US12730754

申请日：2010-03-24

申请人： Michael Joens ,  Ricky F. Baggio

发明人： Michael Joens ,  Ricky F. Baggio

IPC分类号： G01N27/26 ,  G01N21/66 ,  G01N21/64

CPC分类号： G01N21/66 ,  G01N2021/6432

摘要： A system and method are disclosed for utilizing sensors with existing devices. An interface module is used in combination with a newer sensor, such as a fluorescence oxygen sensor, and an older legacy device. The older legacy device supplies a polarizing voltage, and anticipates a measured current of between 0 and 100 nA. The newer sensor requires no polarizing voltage and delivers an output of 0-10 volts in one embodiment, and 4-20 mA in another embodiment. The interface module receives the output from the sensor, and converts it into a useable signal to the legacy device. In another embodiment, the interface module comprises a number of outputs, such that both legacy devices and newer devices can be in communication with the sensor simultaneously. The interface module can be used in conjunction with a reactor chamber or other pharmaceutical process.

摘要翻译： 公开了一种利用现有设备的传感器的系统和方法。 接口模块与较新的传感器（例如荧光氧传感器）和较旧的传统设备结合使用。 较旧的传统设备提供极化电压，并预测0和100 nA之间的测量电流。 较新的传感器在一个实施例中不需要极化电压并输出0-10伏特的输出，而在另一个实施例中输出为4-20mA。 接口模块接收传感器的输出，并将其转换为可用信号到传统设备。 在另一个实施例中，接口模块包括多个输出，使得传统设备和较新设备可以同时与传感器通信。 接口模块可以与反应器室或其它制药工艺结合使用。

公开(公告)号：US20120091012A1

公开(公告)日：2012-04-19

申请号：US13334592

申请日：2011-12-22

申请人： Michael Joens ,  Ricky F. Baggio

发明人： Michael Joens ,  Ricky F. Baggio

IPC分类号： G01N27/26

CPC分类号： G01N21/66 ,  G01N2021/6432

摘要： A system and method are disclosed for utilizing sensors with existing devices. An interface module is used in combination with a newer sensor, such as a fluorescence oxygen sensor, and an older legacy device. The older legacy device supplies a polarizing voltage, and anticipates a measured current of between 0 and 100 nA. The newer sensor requires no polarizing voltage and delivers an output of 0-10 volts in one embodiment, and 4-20 mA in another embodiment. The interface module receives the output from the sensor, and converts it into a useable signal to the legacy device. In another embodiment, the interface module comprises a number of outputs, such that both legacy devices and newer devices can be in communication with the sensor simultaneously. The interface module can be used in conjunction with a reactor chamber or other pharmaceutical process.

摘要翻译： 公开了一种利用现有设备的传感器的系统和方法。 接口模块与较新的传感器（例如荧光氧传感器）和较旧的传统设备结合使用。 较旧的传统设备提供极化电压，并预测0和100 nA之间的测量电流。 较新的传感器在一个实施例中不需要极化电压并输出0-10伏特的输出，而在另一个实施例中输出为4-20mA。 接口模块接收传感器的输出，并将其转换为可用信号到传统设备。 在另一个实施例中，接口模块包括多个输出，使得传统设备和较新设备可以同时与传感器通信。 接口模块可以与反应器室或其它制药工艺结合使用。

公开(公告)号：US08852421B2

公开(公告)日：2014-10-07

申请号：US13334592

申请日：2011-12-22

申请人： Michael Joens ,  Ricky F. Baggio

发明人： Michael Joens ,  Ricky F. Baggio

IPC分类号： G01F1/64 ,  G01N17/00 ,  G01N27/26 ,  G01N21/66 ,  G01N21/64

CPC分类号： G01N21/66 ,  G01N2021/6432

摘要： A system and method are disclosed for utilizing sensors with existing devices. An interface module is used in combination with a newer sensor, such as a fluorescence oxygen sensor, and an older legacy device. The older legacy device supplies a polarizing voltage, and anticipates a measured current of between 0 and 100 nA. The newer sensor requires no polarizing voltage and delivers an output of 0-10 volts in one embodiment, and 4-20 mA in another embodiment. The interface module receives the output from the sensor, and converts it into a useable signal to the legacy device. In another embodiment, the interface module comprises a number of outputs, such that both legacy devices and newer devices can be in communication with the sensor simultaneously. The interface module can be used in conjunction with a reactor chamber or other pharmaceutical process.

公开(公告)号：US20100264041A1

公开(公告)日：2010-10-21

申请号：US12730754

申请日：2010-03-24

申请人： Michael Joens ,  Ricky F. Baggio

发明人： Michael Joens ,  Ricky F. Baggio

IPC分类号： G01N27/26

CPC分类号： G01N21/66 ,  G01N2021/6432

摘要： A system and method are disclosed for utilizing sensors with existing devices. An interface module is used in combination with a newer sensor, such as a fluorescence oxygen sensor, and an older legacy device. The older legacy device supplies a polarizing voltage, and anticipates a measured current of between 0 and 100 nA. The newer sensor requires no polarizing voltage and delivers an output of 0-10 volts in one embodiment, and 4-20 mA in another embodiment. The interface module receives the output from the sensor, and converts it into a useable signal to the legacy device. In another embodiment, the interface module comprises a number of outputs, such that both legacy devices and newer devices can be in communication with the sensor simultaneously. The interface module can be used in conjunction with a reactor chamber or other pharmaceutical process.

摘要翻译： 公开了一种利用现有设备的传感器的系统和方法。 接口模块与较新的传感器（例如荧光氧传感器）和较旧的传统设备结合使用。 较旧的传统设备提供极化电压，并预测0和100 nA之间的测量电流。 较新的传感器在一个实施例中不需要极化电压并输出0-10伏特的输出，而在另一个实施例中输出为4-20mA。 接口模块接收传感器的输出，并将其转换为可用信号到传统设备。 在另一个实施例中，接口模块包括多个输出，使得传统设备和较新设备可以同时与传感器通信。 接口模块可以与反应器室或其它制药工艺结合使用。