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公开(公告)号：US10398853B2
公开(公告)日：2019-09-03
申请号：US15375611
申请日：2016-12-12
Applicant: Roche Diagnostics International AG
Inventor： Christoph Huwiler , Florian Kuhni , Andreas Geipel
Abstract: Bubble traps for removing bubbles from a stream of liquid and flexible containers comprising such bubble traps are disclosed. The bubble trap includes a containment chamber fluidly coupled to an outlet conduit. At least one grate is disposed between the containment chamber and the outlet conduit. The at least one grate includes a plurality of grate inlets formed in a grate wall and fluidly coupled to the outlet conduit with a plurality of grate conduits such that the containment chamber is fluidly coupled to the outlet conduit. The grate traps bubbles entrained in the stream of liquid flowing from the containment chamber to the outlet conduit in the containment chamber when the bubbles are greater than or equal to a diameter of the grate inlets.
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公开(公告)号：US10045910B2
公开(公告)日：2018-08-14
申请号：US15016511
申请日：2016-02-05
Applicant: Roche Diagnostics International AG
Inventor： Marcel Mueller , Maurice Ducret
CPC classification number: A61J1/2065 , A61J1/1406 , A61J1/2013 , A61J1/2051 , A61J1/2055 , A61J1/2089 , A61M39/14 , A61M2039/0027
Abstract: A connector device for connecting two containers with first and second members slidably displaceable in regard to each other along an axis between a first and a second position is presented. The first member comprises a needle parallel to the axis so that the first container's septum is penetrated by one end of the needle when the first container is introduced into the first member. The second member comprises a coupling to the second container. The other needle end penetrates the second container's septum when the members are in the second position establishing a connection between the two containers. The first member comprises a coupling to the second container coupled to the second member. The first member can couple to the second container when the two members are in the second position and cannot couple to the second container when the two members are in the first position.
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公开(公告)号：US20170100537A1
公开(公告)日：2017-04-13
申请号：US15386026
申请日：2016-12-21
Applicant: Roche Diagnostics International AG
Inventor： Ulrich Haueter , Florian Kuehni
IPC: A61M5/168
CPC classification number: A61M5/168 , A61M5/14 , A61M5/14216 , A61M5/152 , A61M5/16809 , A61M5/1684 , A61M5/16854 , A61M5/16859 , A61M5/16881 , A61M5/31525 , A61M39/24 , A61M2005/16863 , A61M2205/15 , A61M2205/3331 , A61M2205/3379 , A61M2205/7536 , F04B53/162 , G01F11/04
Abstract: A dosing device for an infusion system comprises a dosing unit having a variable volume and at least one opening in fluid connection with the variable volume, through which opening the variable volume can be filled with a substance or the substance can be dispensed from the variable volume. The dosing device is operable in a first state for filling the substance from a supply conduit, in a second state for preventing filling and dispensing, or in a third state for dispensing through a dispensing conduit. No direct fluid connection exists between the supply conduit and the dispensing conduit at any time. Methods for dosing a substance with the dosing device.
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公开(公告)号：US09610400B2
公开(公告)日：2017-04-04
申请号：US14049349
申请日：2013-10-09
Applicant: Roche Diagnostics International AG
Inventor： Franco Moia , Marcel Mueller , Maurice Ducret
CPC classification number: A61M5/14216 , A61J1/062 , A61M5/14566 , A61M5/1458 , A61M5/1782 , A61M5/31515 , B23P15/10 , Y10T29/49252
Abstract: A device for moving a piston inside a cartridge having a cartridge body and the piston displaceable along a longitudinal axis of the cartridge body is presented. The device comprises a first portion having first coupler for coupling the cartridge body to the first portion such that in both directions of the longitudinal axis, a connection exists between the cartridge body and the first portion; and a second portion having second coupler for coupling the piston to the second portion such that in both directions of the longitudinal axis, a connection exists between the piston and the second portion. The first and second portions move relative to each other to effect at least a forward displacement of the piston coupled to the second portion inside the cartridge body coupled to the first portion along the longitudinal axis. The second coupler establishes and releases the connection with the piston.
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5.发明授权Ambulatory infusion device with replaceable energy storage and method of monitoring the energy storage 有权具有可更换能量存储的动态输液装置和监测储能的方法
公开(公告)号：US09377513B2
公开(公告)日：2016-06-28
申请号：US13761215
申请日：2013-02-07
Applicant: Roche Diagnostics International AG
Inventor： Stefan Lindegger
CPC classification number: G01R31/362 , A61M5/14 , A61M5/1413 , A61M5/14244 , A61M5/16831 , A61M5/172
Abstract: An ambulatory infusion device comprising a replaceable energy storage for electrically powering its functional units is presented. Control units provide to a monitoring system data about energy consuming activities or consumed energy by the functional units. Based on this data, the monitoring system determines energy consumed by the functional units and triggers measurement of the voltage of the energy storage at a point in time which depends on the determined energy consumed in a time interval preceding the point in time. Adapting the time of measurement to the actual energy drawn from the energy storage makes it possible to detect reliably and early a low energy state of any conventional standard battery, regardless of its electrochemical design and electrical behavior.
Abstract translation: 提出了包括用于为其功能单元供电的可替换能量存储器的流动输注装置。 控制单元向监控系统提供关于功能单元的能量消耗活动或消耗能量的数据。 基于该数据，监视系统确定功能单元消耗的能量，并且触发在取决于在时间点之前的时间间隔内消耗的确定的能量的时间点上的能量存储器的电压的测量。 将测量时间适应于从能量存储器抽取的实际能量，使得无论其电化学设计和电气行为如何，都可以可靠地且早期地检测任何常规标准电池的低能态。
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6.发明申请APPARATUSES, SYSTEMS, AND METHODS FOR FILLING A CONTAINER WITH A LIQUID DRUG 审中-公开用液体液体填充容器的装置，系统和方法
公开(公告)号：US20150290082A1
公开(公告)日：2015-10-15
申请号：US14751778
申请日：2015-06-26
Applicant: Roche Diagnostics International AG
Inventor： Roger Haenggi , Urs Rindlisbacher , Franco Moia , Marcel Mueller , Christoph Huwiler , Florian Kuhni , Joerg Wermelinger , Andreas Lischewski , Christian Classen , Tilo Callenbach , Louis Widmer , Maurice Ducret
CPC classification number: A61J1/2096 , A61J1/20 , A61J1/201 , A61J1/2048 , A61M5/24 , B65B3/003
Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.
Abstract translation: 在一个实施例中，从药物储存器填充液体药物的容器的方法可以包括：a）将容器和药物储存器与套管连接，使得药物储存器和容器经由套管彼此流体连通， 同时密封; b）减少容纳在容器内的第一容积，以将气态介质从容器的第一容积经由套管置换成容纳在药物贮存器内的第二容积; c）增加容器的第一容积以将液体药物从药物储存器的第二体积移位到容器的第一容积中以填充容器; 和d）断开容器和药物储存器。 在执行动作d）之前，动作b）和动作c）可以连续执行多次以逐步增加液体药物的移动量。
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公开(公告)号：US09095659B2
公开(公告)日：2015-08-04
申请号：US14100769
申请日：2013-12-09
Applicant: Roche Diagnostics International AG
Inventor： Christian Thalmann , Simon Scheurer
CPC classification number: A61M5/3202 , A61M5/158 , A61M2005/1583 , A61M2005/1585 , A61M2005/1587
Abstract: An insertion head for medical or pharmaceutical applications includes a base having a lower side which can be positioned on organic tissue; an insertion means movably mounted by the base and insertable into the tissue; where the insertion means is movable relative to the base from a protective position in which a free end of the insertion means is short of the lower side of the base, into an insertion position in which the free end protrudes beyond the lower side; a handle which projects from the base and includes a first handle component and a second handle component movable relative to the base and the first handle component; and a coupling that transmits a movement of the second handle component into a movement of the insertion means.
Abstract translation: 用于医疗或药物应用的插入头包括具有可以位于有机组织上的下侧的基部; 插入装置，其可移动地由所述基座安装并且可插入所述组织中; 其中所述插入装置可相对于所述基座从所述插入装置的自由端短于所述基座的下侧的保护位置移动到所述自由端突出超过所述下侧的插入位置; 手柄，其从基座突出并且包括第一手柄部件和可相对于基部和第一手柄部件移动的第二手柄部件; 以及将所述第二手柄部件的运动传递到所述插入装置的运动的联接器。
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公开(公告)号：US08977883B2
公开(公告)日：2015-03-10
申请号：US13681693
申请日：2012-11-20
Inventor： Erich Imhof , Guido Konrad , James R. Long , Phillip E. Pash , Robert E. Reinke
CPC classification number: A61M5/1723 , G06F19/00 , G06F19/3468 , G16H40/40
Abstract: A computer-implemented method is presented for synchronizing time between two handheld medical devices that interoperate with each other. The method includes: determining a first time as measured by a first clock residing in the first medical device; determining a second time as measured by a second clock residing in a second medical device; evaluating whether the first clock is synchronized with the second clock; determining whether at least one of the first clock and the second clock was set manually by a user; and setting time of the first clock in accordance with the second time when the second clock was set manually by the user.
Abstract translation: 提出了一种计算机实现的方法，用于在彼此互操作的两个手持医疗设备之间同步时间。 该方法包括：通过驻留在第一医疗设备中的第一时钟来测量第一时间; 确定由驻留在第二医疗装置中的第二时钟测量的第二时间; 评估所述第一时钟是否与所述第二时钟同步; 确定所述第一时钟和所述第二时钟中的至少一个是否由用户手动设置; 并且根据用户手动设置第二时钟的第二时间来设置第一时钟的设置时间。
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公开(公告)号：US20130163769A1
公开(公告)日：2013-06-27
申请号：US13773093
申请日：2013-02-21
Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AG
Inventor： Lucas Kalt , Axel Remde
CPC classification number: A61M5/14244 , A61B5/14532 , A61M2205/186 , A61M2205/581 , A61M2205/70 , A61M2205/702 , G10K15/02 , H04R29/00
Abstract: An ambulatory medical device is presented. The ambulatory medical device comprises a function module to provide the intended functionality of the device, a controller module to control the device, a sound generation module with an acoustic transducer to produce an acoustic signal and a signal generator to drive the acoustic transducer with a certain frequency. The signal generation module is arranged within a housing of the device. A tuning module varies the frequency used by the signal generator to drive the acoustic transducer and determines one or more frequencies that correspond to an optimum sound level of the acoustic signal outside of the housing of the device. The optimum sound level of the acoustic signal is a maximum sound level outside of the housing of the device, and/or a maximum perceivable sound level as determined by a user.
Abstract translation: 介绍了一种动态医疗设备。 移动医疗装置包括提供装置的预期功能的功能模块，用于控制装置的控制器模块，具有声换能器以产生声信号的声音产生模块和用于以一定的速度驱动声换能器的信号发生器 频率。 信号发生模块布置在设备的壳体内。 调谐模块改变信号发生器使用的频率来驱动声换能器并且确定对应于设备壳体外部的声信号的最佳声级的一个或多个频率。 声信号的最佳声级是设备外壳之外的最大声级和/或由用户确定的最大可感知声级。
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公开(公告)号：US20130158486A1
公开(公告)日：2013-06-20
申请号：US13783500
申请日：2013-03-04
Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AG
Inventor： Ruedi Zihlmann , Ronny-Patric Horisberger , Daniel Fehlmann
IPC: A61M5/315
CPC classification number: A61M5/31501 , A61L2/06 , A61L2/07 , A61L2/08 , A61L2/081 , A61L2/20 , A61L2/204 , A61L2/206 , A61M5/1408 , A61M5/19 , A61M5/3129 , A61M5/315 , A61M2005/3123 , A61M2005/31506 , A61M2005/31508
Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes at least one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has a first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.
Abstract translation: 用于分配可流动物质的安瓿和包含其的计量系统在此描述。 用于可流动物质的安瓿包括安瓿本体，其包括用于接收可流动物质的内部空间和具有引导区域和密封区域的内周面。 活塞可以设置在安瓿主体的内部空间中，使得活塞沿着位移方向可滑动地移动。 活塞包括至少一个密封元件，用于在密封元件的外圆周上的接触区域中与内周表面形成密封。 当接触区域处于引导区域时，密封元件具有第一压缩状态，当接触区域处于密封区域时，密封元件具有第二压缩状态。 第二阻挡装置防止接触区从密封区域移动到引导区域。
