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9 条记录 (耗时 0.013 秒)

    Dissolution test apparatus
    1.
    发明授权
    Dissolution test apparatus 失效
    溶解试验装置

    公开(公告)号：US5639974A

    公开(公告)日：1997-06-17

    申请号：US625160

    申请日：1996-04-01

    申请人： Royal A. Hanson ,  Bruce E. Renslow

    发明人： Royal A. Hanson ,  Bruce E. Renslow

    IPC分类号： B01F1/00 ,  B01F7/16 ,  G01N13/00

    CPC分类号： B01F1/0011 ,  B01F7/161 ,  G01N13/00 ,  B01F2215/0037 ,  G01N2013/003 ,  G01N2013/006

    摘要： A dissolution test apparatus which utilizes a fixed base upon which is movably mounted a drive head, The fixed base which supports a plurality of flasks. Mounted within the drive head are a plurality of mixing paddles, The drive head is to be manually movable from the upper position to a lower position, In the lower position each mixing paddle to be located within a flask. Also mounted in the drive head is a plurality of sample tubes with a sample tube to be located in direct juxtaposition to a mixing paddle, Each sample tube is separately movable relative to the drive head. With the drive head in the upper position the mixing paddles are located spaced from their respective flasks. The weight of the drive head is counterbalanced by a counterbalancing weight assembly. A caliper type of braking arrangement is mounted on the drive head and when in the at-rest position the drive head is fixedly positioned relative to the base. Manual release of the braking arrangement will permit the drive head to be moved between the upper and lower positions relative to the base.

    摘要翻译： 溶解试验装置，其利用固定基座，可移动地安装驱动头。支撑多个烧瓶的固定基座。 安装在驱动头内的是多个混合桨。驱动头可以从上部位置手动地移动到下部位置。在下部位置，每个混合桨位于烧瓶内。 还安装在驱动头中的是具有样品管的多个样品管，其位于与混合桨直接并置的位置。每个样品管可相对于驱动头分开移动。 当驱动头处于上部位置时，混合桨与它们各自的烧瓶间隔开。 驱动头的重量由平衡配重组件抵消。 卡钳式制动装置安装在驱动头上，当处于静止位置时，驱动头相对于底座固定地定位。 制动装置的手动释放将允许驱动头相对于底座在上下位置之间移动。

    Dissolution test apparatus with counterbalance system
    4.
    发明授权
    Dissolution test apparatus with counterbalance system 失效
    具有平衡系统的溶出度试验装置

    公开(公告)号：US5682001A

    公开(公告)日：1997-10-28

    申请号：US711328

    申请日：1996-09-03

    申请人： Royal A. Hanson ,  Bruce E. Renslow

    发明人： Royal A. Hanson ,  Bruce E. Renslow

    IPC分类号： B01F1/00 ,  B01F7/16 ,  G01N13/00 ,  B01F15/60

    CPC分类号： B01F1/0011 ,  B01F7/161 ,  G01N13/00 ,  B01F2215/0037 ,  G01N2013/003 ,  G01N2013/006

    摘要： A dissolution test apparatus which utilizes a fixed base upon which is movably mounted a drive head. The fixed base which supports a plurality of flasks. Mounted within the drive head are a plurality of mixing paddles. The drive head is to be manually movable from the upper position to a lower position. In the lower position each mixing paddle to be located within a flask. Also mounted in the drive head is a plurality of sample tubes with a sample tube to be located in direct juxtaposition to a mixing paddle. Each sample tube is separately movable relative to the drive head. With the drive head in the upper position the mixing paddles are located spaced from their respective flasks. The weight of the drive head is counterbalanced by a counterbalancing weight assembly. A caliper type of braking arrangement is mounted on the drive head and when in the at-rest position the drive head is fixedly positioned relative to the base. Manual release of the braking arrangement will permit the drive head to be moved between the upper and lower positions relative to the base.

    摘要翻译： 一种溶解试验装置，其利用固定基座，可移动地安装驱动头。 支撑多个烧瓶的固定基座。 安装在驱动头内的是多个混合桨。 驱动头可以从上部位置手动移动到下部位置。 在较低位置，每个混合桨将位于烧瓶内。 还安装在驱动头中的是具有样品管的多个样品管，其位于与混合桨直接并置的位置。 每个样品管可以相对于驱动头分开移动。 当驱动头处于上部位置时，混合桨与它们各自的烧瓶间隔开。 驱动头的重量由平衡配重组件抵消。 卡钳式制动装置安装在驱动头上，当处于静止位置时，驱动头相对于底座固定地定位。 制动装置的手动释放将允许驱动头相对于底座在上下位置之间移动。

    Diffusion cell with quick release clamp
    6.
    发明授权
    Diffusion cell with quick release clamp 有权
    具有快速释放夹的扩散槽

    公开(公告)号：US06821419B2

    公开(公告)日：2004-11-23

    申请号：US10056186

    申请日：2002-01-28

    申请人： Royal A. Hanson ,  Bruce E. Renslow ,  Steven W. Shaw ,  Jerome S. Elkins

    发明人： Royal A. Hanson ,  Bruce E. Renslow ,  Steven W. Shaw ,  Jerome S. Elkins

    IPC分类号： B01D6508

    CPC分类号： G01N13/00 ,  G01N2001/4016 ,  G01N2013/003

    摘要： A diffusion cell to facilitate the automatic or manual removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percantaneous absorption through a membrane of a substance from a donor chamber into a receptor chamber of the diffusion cell. There is utilized a capillary port through which the test aliquot is to be removed. A refilling tube connects also with the receptor chamber to add receptor liquid into the receptor chamber as the test aliquot is being removed. A quick release clamping apparatus secures the donor housing which contains the donor chamber tightly to the main housing of the diffusion cell.

    摘要翻译： 扩散池，用于自动或手动地从扩散池的受体室移除液体的试样等分试样，以便确定通过物质膜从供体室到扩散池的受体室的吸收。 使用毛细管端口，通过该毛细管孔将待除去的试样等分试样。 当试剂等分试样被去除时，再填充管还与受体室连接，以将受体液体加入到受体室中。 快速释放夹紧装置将包含供体室的供体壳固定到扩散池的主壳体上。

    Dissolution sampling apparatus
    7.
    发明授权
    Dissolution sampling apparatus 有权
    溶出采样仪

    公开(公告)号：US06422098B1

    公开(公告)日：2002-07-23

    申请号：US09407700

    申请日：1999-09-28

    申请人： Royal A. Hanson ,  Bruce E. Renslow ,  Guillermo E. Meneses ,  Steven W. Shaw ,  Robinson C. Russell

    发明人： Royal A. Hanson ,  Bruce E. Renslow ,  Guillermo E. Meneses ,  Steven W. Shaw ,  Robinson C. Russell

    IPC分类号： G06F1546

    CPC分类号： G01N13/00 ,  G01N2013/006

    摘要： A dissolution sampling apparatus which automatically extracts aliquots which contain a dissolved drug in solution from a plurality of dissolution containing flasks and tests each aliquot for the amount of drug dissolved within the aliquot. The sampling apparatus can resupply the removed aliquot. back to its source or the aliquot can be discarded as waste with new media being resupplied to the source. A syringe is used to remove the aliquots. A mechanically operated valve could be used with each syringe or a plurality of solenoids instead of the mechanically operated valve.

    摘要翻译： 一种溶出取样装置，其自动地从多个溶解容器中提取含有溶解的溶解药物的等分试样，并测试每个等分试样中溶解在等分试样中的药物的量。 采样设备可以重新供应取出的等分试样。 回到其来源或等分试样可以作为废物被丢弃，新的媒体被重新供应给源。 使用注射器去除等分试样。 每个注射器或多个螺线管可以使用机械操作的阀，而不是机械操作的阀。