SYSTEM FOR MONITORING OF PATIENTS
    1.
    发明申请
    SYSTEM FOR MONITORING OF PATIENTS 审中-公开
    系统监测患者

    公开(公告)号:US20090137888A9

    公开(公告)日:2009-05-28

    申请号:US11422561

    申请日:2006-06-06

    IPC分类号: A61B5/05 A61B5/00

    摘要: A patient monitoring system implemented by a service provider for users via recording a patient's analytes measurements by non-invasively interrogating a skin patch placed upon the patient's skin surface. The system includes an input module to provide a device to measure analytes from a patient, such as a measurement of the blood glucose level. The measurement is shared among a plurality of output devices such as computers, personal digital assistants (PDAs), cellular phones, and pagers that are stationed or held by various users, such as doctors, patients, researchers, pharmacies, labs, and health insurers. In addition, behavioral attributes are recorded and correlated with the analytes measurements to generate a profile. The profile is selectively sent to output devices based on the user profile corresponding to the output device. Also, access to the profile is monitored by a security module that encrypts the profile to prevent access by un-authorized users.

    摘要翻译: 由服务提供商为用户实施的患者监测系统,其通过非侵入式询问放置在患者皮肤表面上的皮肤贴片来记录患者的分析物测量值。 该系统包括输入模块,用于提供测量来自患者的分析物的装置,例如测量血糖水平。 诸如医生,病人,研究人员,药房,实验室和健康保险公司等各种用户所驻扎或持有的多个输出设备如计算机,个人数字助理(PDA),蜂窝电话和寻呼机共享测量。 。 此外,记录行为属性并与分析物测量相关联以生成轮廓。 基于与输出设备相对应的用户简档,该配置文件被选择性地发送到输出设备。 此外,对配置文件的访问由加密配置文件以防止未经授权的用户访问的安全模块进行监控。

    Formulation and manipulation of databases of analyte and associated values
    7.
    发明申请
    Formulation and manipulation of databases of analyte and associated values 有权
    分析物和相关值的数据库的制备和操作

    公开(公告)号:US20050010093A1

    公开(公告)日:2005-01-13

    申请号:US10821055

    申请日:2004-04-08

    IPC分类号: G06F19/00 A61B5/00

    摘要: The present invention relates to methods of formulating analyte data databases, the databases themselves, and methods of manipulating the same. In one aspect the present invention includes the formulation of analyte data points, derived data, and data attributes databases comprising data points collected using an analyte monitoring device capable of frequent monitoring of analyte concentrations or amounts. Such data points may comprise acquired data (e.g., values corresponding to analyte concentrations or amounts as measured by said analyte monitoring device). These data points are then associated with one or more relevant data attributes. The resulting databases may be manipulated to determine relationships among the components of the database.

    摘要翻译: 本发明涉及配制分析物数据数据库的方法,数据库本身及其操作方法。 一方面,本发明包括分析物数据点,派生数据和数据属性数据库的配方,其包括使用能够频繁地监测分析物浓度或量的分析物监测装置收集的数据点。 这样的数据点可以包括获取的数据(例如,对应于由所述分析物监测装置测量的分析物浓度或量的值)。 然后将这些数据点与一个或多个相关数据属性相关联。 可以操纵生成的数据库以确定数据库的组件之间的关系。

    Patches, systems, and methods for non-invasive glucose measurement
    8.
    发明申请
    Patches, systems, and methods for non-invasive glucose measurement 审中-公开
    用于非侵入性葡萄糖测量的补片,系统和方法

    公开(公告)号:US20070179371A1

    公开(公告)日:2007-08-02

    申请号:US11528750

    申请日:2006-09-27

    IPC分类号: A61B5/05 A61B5/00

    摘要: Described here are patches, systems, and methods for measuring glucose. In general, the patches comprise a microfluidic collection layer and a detector, and the systems comprise a patch and a measurement device. Some methods for measuring glucose comprise cleaning the skin surface, collecting sweat from the skin surface using a microfluidic collection device, and measuring the collected glucose. Other methods comprise cleaning the skin surface, collecting sweat in a patch comprising a microfludic collection layer, and measuring glucose collected in the patch. Still other methods comprise cleaning the skin surface, collecting a first sweat sample from the skin surface in a patch comprising a microfludic collection layer and a detector layer, transferring the first sweat sample from the collection layer to the detector layer, measuring glucose in the first sweat sample, and repeating the collection, transferring, and measuring steps at least once.

    摘要翻译: 这里描述了用于测量葡萄糖的补丁,系统和方法。 通常,贴片包括微流体收集层和检测器,并且系统包括贴片和测量装置。 用于测量葡萄糖的一些方法包括清洁皮肤表面,使用微流体收集装置从皮肤表面收集汗液,以及测量收集的葡萄糖。 其他方法包括清洁皮肤表面,在包含微量收集层的贴片中收集汗液,以及测量在贴片中收集的葡萄糖。 还有其它方法包括清洁皮肤表面,在包括微量收集层和检测器层的贴片中从皮肤表面收集第一汗液样品,将第一汗液样品从收集层转移到检测器层,测量第一汗液样品中的葡萄糖 汗液样品,并重复收集,转移和测量步骤至少一次。

    Devices, methods, and kits for non-invasive glucose measurement
    9.
    发明申请
    Devices, methods, and kits for non-invasive glucose measurement 失效
    用于非侵入性葡萄糖测量的装置,方法和试剂盒

    公开(公告)号:US20060004271A1

    公开(公告)日:2006-01-05

    申请号:US11159587

    申请日:2005-06-22

    IPC分类号: A61B5/00

    摘要: Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.

    摘要翻译: 描述了用于非侵入性测量葡萄糖的装置,方法和试剂盒。 通常,这些装置包括用于放置在皮肤表面上的皮肤贴片和用于测量在贴片中收集的葡萄糖的测量装置。 贴剂可以包括粘合剂材料,收集层,界面层和汗液渗透膜。 透汗膜被配置为作为通过扩散带到皮肤表面的表皮污染物和葡萄糖的屏障。 以这种方式,不能测量不相关的皮肤表面葡萄糖。 补片还可以包括诱发局部汗水反应的组件。 测量装置通常包括显示器,处理器和测量机构。 所述方法通常包括以下步骤:用含有至少一种用于除去葡萄糖的溶剂的擦拭物擦拭皮肤表面,将贴片放置在皮肤表面上,以及测量在贴剂中收集的葡萄糖。 还描述了包括贴剂和测量装置的试剂盒。

    Methods for estimating analyte-related signals, microprocessors comprising programming to control performance of the methods, and analyte monitoring devices employing the methods
    10.
    发明申请
    Methods for estimating analyte-related signals, microprocessors comprising programming to control performance of the methods, and analyte monitoring devices employing the methods 有权
    用于估计分析物相关信号的方法,包括用于控制方法性能的编程的微处理器以及采用该方法的分析物监测装置

    公开(公告)号:US20050049473A1

    公开(公告)日:2005-03-03

    申请号:US10963853

    申请日:2004-10-13

    IPC分类号: A61B5/00 A61N1/30 A61B5/05

    摘要: The present invention relates to methods to increase the number of analyte-related signals used to provide analyte measurement values, e.g., when two or more analyte-related signals are used to obtain a single analyte measurement value a “rolling” value based on the two or more signals can be employed. In another aspect, interpolation and/or extrapolation methods are used to estimate unusable, missing or error-associated analyte-related signals. Further, interpolation and extrapolation of values are employed in another aspect of the invention that reduces the incident of failed calibrations. Further, the invention relates to methods, which employ gradients and/or predictive algorithms, to provide an alert related to analyte values exceeding predetermined thresholds. The invention includes the above-described methods, one or more microprocessors programmed to execute the methods, one or more microprocessors programmed to execute the methods and control at least one sensing and/or sampling device, and monitoring systems employing the methods described herein.

    摘要翻译: 本发明涉及增加用于提供分析物测量值的分析物相关信号的数量的方法,例如当使用两个或更多个与分析物相关的信号来获得单个分析物测量值时,基于两个分析物相关信号的“滚动”值 或更多的信号。 在另一方面,内插和/或外插方法用于估计不可用,缺失或与误差相关的分析物相关信号。 此外,在本发明的另一方面,采用了内插和外推值来减少校准失败的事件。 此外,本发明涉及采用梯度和/或预测算法来提供与超过预定阈值的分析物值相关的警报的方法。 本发明包括上述方法,被编程为执行方法的一个或多个微处理器,被编程为执行方法和控制至少一个感测和/或采样装置的一个或多个微处理器,以及采用本文描述的方法的监视系统。