公开(公告)号：US08349595B2

公开(公告)日：2013-01-08

申请号：US12524647

申请日：2008-01-25

申请人： Masahiro Hayashi ,  Sanae Nakajima ,  Naoki Nagano ,  Yosuke Taoka

发明人： Masahiro Hayashi ,  Sanae Nakajima ,  Naoki Nagano ,  Yosuke Taoka

IPC分类号： C12P7/64 ,  C12N1/12 ,  C07C57/03

CPC分类号： C12P7/6427 ,  C11C3/00 ,  C12N1/14 ,  C12P7/6472

摘要： [PROBLEMS] To provide a fat-and-oil in which the content of docosahexaenoic acid is increased.[MEANS FOR SOLVING PROBLEMS] A process for producing highly unsaturated fatty acids comprising culturing a stramenopile capable of producing highly unsaturated fatty acids in a culture medium containing an inhibitor for fatty acid desaturases; fats-and-oils in which the content of highly unsaturated fatty acids, particularly docosahexaenoic acid produced by the relevant method, is increased. A method for enhancing the productivity of highly unsaturated fatty acids in stramenopiles, comprising culturing a stramenopile in a culture medium containing an inhibitor for fatty acid desaturases; stramenopiles having the enhanced productivity of highly unsaturated fatty acids, generated by the relevant method. Particularly, the process for producing highly unsaturated fatty acids, the method for enhancing the productivity of highly unsaturated fatty acids, and the stramenopile having the enhanced productivity of highly unsaturated fatty acids, wherein the stramenopile is a microorganism classified into Labyrinthulea.

摘要翻译： [问题]提供其中二十二碳六烯酸含量增加的脂肪和油。 解决问题的手段一种高不饱和脂肪酸的制造方法，其特征在于，在含有脂肪酸去饱和酶抑制剂的培养基中培养能够生产高度不饱和脂肪酸的前列腺素; 其中通过相关方法生产的高度不饱和脂肪酸，特别是二十二碳六烯酸的含量增加的脂肪和油。 一种增强层状高分子量不饱和脂肪酸的生产率的方法，包括在含有脂肪酸去饱和酶抑制剂的培养基中培养前列腺素; 具有通过相关方法生成的高度不饱和脂肪酸的生产率提高的前列腺素。 特别是生产高不饱和脂肪酸的方法，提高高不饱和脂肪酸的生产率的方法以及具有提高的高度不饱和脂肪酸的生产率的前列腺素，其中所述地釉菌是分类为迷迭虫的微生物。

公开(公告)号：US20100099901A1

公开(公告)日：2010-04-22

申请号：US12524647

申请日：2008-01-25

申请人： Masahiro Hayashi ,  Sanae Nakajima ,  Naoki Nagano ,  Yosuke Taoka

发明人： Masahiro Hayashi ,  Sanae Nakajima ,  Naoki Nagano ,  Yosuke Taoka

IPC分类号： C07C57/03 ,  C12P7/64 ,  C12N1/12

CPC分类号： C12P7/6427 ,  C11C3/00 ,  C12N1/14 ,  C12P7/6472

摘要： [PROBLEMS] To provide a fat-and-oil in which the content of docosahexaenoic acid is increased.[MEANS FOR SOLVING PROBLEMS] A process for producing highly unsaturated fatty acids comprising culturing a stramenopile capable of producing highly unsaturated fatty acids in a culture medium containing an inhibitor for fatty acid desaturases; fats-and-oils in which the content of highly unsaturated fatty acids, particularly docosahexaenoic acid produced by the relevant method, is increased. A method for enhancing the productivity of highly unsaturated fatty acids in stramenopiles, comprising culturing a stramenopile in a culture medium containing an inhibitor for fatty acid desaturases; stramenopiles having the enhanced productivity of highly unsaturated fatty acids, generated by the relevant method. Particularly, the process for producing highly unsaturated fatty acids, the method for enhancing the productivity of highly unsaturated fatty acids, and the stramenopile having the enhanced productivity of highly unsaturated fatty acids, wherein the stramenopile is a microorganism classified into Labyrinthulea.

摘要翻译： [问题]提供其中二十二碳六烯酸含量增加的脂肪和油。 解决问题的手段一种高不饱和脂肪酸的制造方法，其特征在于，在含有脂肪酸去饱和酶抑制剂的培养基中培养能够生产高度不饱和脂肪酸的前列腺素; 其中通过相关方法生产的高度不饱和脂肪酸，特别是二十二碳六烯酸的含量增加的脂肪和油。 一种增强层状高分子量不饱和脂肪酸的生产率的方法，包括在含有脂肪酸去饱和酶抑制剂的培养基中培养前列腺素; 具有通过相关方法生成的高度不饱和脂肪酸的生产率提高的前列腺素。 特别是生产高不饱和脂肪酸的方法，提高高不饱和脂肪酸的生产率的方法以及具有提高的高度不饱和脂肪酸的生产率的前列腺素，其中所述地釉菌是分类为迷迭虫的微生物。