利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

29 条记录 (耗时 0.038 秒)

    Physiochemically controlled scour jet array system
    3.
    发明授权
    Physiochemically controlled scour jet array system 失效
    生理控制冲刷喷射阵列系统

    公开(公告)号：US4506686A

    公开(公告)日：1985-03-26

    申请号：US584834

    申请日：1984-02-29

    申请人： James A. Bailard ,  Scott A. Jenkins

    发明人： James A. Bailard ,  Scott A. Jenkins

    IPC分类号： B05B12/12 ,  B08B3/08 ,  B08B17/00 ,  E02B3/02 ,  B63B59/04 ,  G05D21/00

    CPC分类号： E02B3/023 ,  B05B12/12 ,  B08B17/00 ,  B08B3/08 ,  Y10T137/0801 ,  Y10T137/2509

    摘要： The scour jet array system includes a pump, both fresh water and surface er intakes, an automatic water mixing valve, a chemical buffer injector, a water heater, a series of scour jets with control valves, and a central control system.The control system senses the beginning of ebb tide for starting an initial scour jet, and as each jet scours the freshly deposited mud from the area, temperature, salinity and pH of the surface suction intake water are measured to determine the amount of fresh water injection, chemical buffer injection, water heating and duty cycle time in order to minimize the energy required to scour the sediments from the area.

    摘要翻译： 冲洗喷射阵列系统包括一个泵，包括淡水和地表进水口，自动水混合阀，化学缓冲注射器，热水器，一系列具有控制阀的冲洗喷嘴和中央控制系统。 控制系统检测开始初始冲刷射流的起始潮，并且当每个喷射器从该区域冲洗新沉积的泥浆时，测量表面吸入水的温度，盐度和pH值以确定淡水注入量 ，化学缓冲液注入，水加热和占空比时间，以便最小化从该地区冲洗沉积物所需的能量。

    Nanoparticulate and controlled release compositions comprising cefditoren
    5.
    发明授权
    Nanoparticulate and controlled release compositions comprising cefditoren 有权
    包含头孢托仑的纳米颗粒和控释组合物

    公开(公告)号：US08119163B2

    公开(公告)日：2012-02-21

    申请号：US11671276

    申请日：2007-02-05

    申请人： John G Devane ,  Paul Stark ,  Niall M. N. Fanning ,  Gurvinder Singh Rekhi ,  Scott A. Jenkins ,  Gary Liversidge

    发明人： John G Devane ,  Paul Stark ,  Niall M. N. Fanning ,  Gurvinder Singh Rekhi ,  Scott A. Jenkins ,  Gary Liversidge

    IPC分类号： A61K9/14 ,  A61K9/16 ,  A61K9/50 ,  A61K9/54

    CPC分类号： A61K9/5084

    摘要： The present invention provides a composition comprising a cefditoren, or a salt, derivative, prodrug, or other form thereof, for example, cefditoren pivoxil, useful in the treatment and prevention of infections and related conditions. The invention provides a composition which comprises nanoparticulate particles comprising the cefditoren, or a salt, derivative, prodrug, or other form thereof and at least one surface stabilizer. The nanoparticulate particles have an effective average particle size of less than about 2000 nm. The invention provides also a composition that delivers a cefditoren, or a salt, derivative, prodrug, or other form thereof, or nanoparticles comprising the same, in a pulsatile or continuous manner.

    摘要翻译： 本发明提供一种组合物，其包含可用于治疗和预防感染和相关病症的头孢托仑或其盐，衍生物，前药或其他形式，例如匹戊头孢托仑。 本发明提供一种组合物，其包含包含头孢托仑或其盐，衍生物，前药或其它形式的纳米颗粒颗粒和至少一种表面稳定剂。 纳米颗粒具有小于约2000nm的有效平均粒度。 本发明还提供以脉动或连续方式递送头孢托仑或其盐衍生物，前药或其它形式或包含其的纳米颗粒的组合物。

    NANOPARTICULATE AND CONTROLLED RELEASE COMPOSITIONS COMPRISING CYCLOSPORINE
    6.
    发明申请
    NANOPARTICULATE AND CONTROLLED RELEASE COMPOSITIONS COMPRISING CYCLOSPORINE 审中-公开
    包含环磷酰胺的纳米颗粒和控制释放组合物

    公开(公告)号：US20110064800A1

    公开(公告)日：2011-03-17

    申请号：US12888530

    申请日：2010-09-23

    申请人： Scott A. Jenkins ,  Gary Liversidge

    发明人： Scott A. Jenkins ,  Gary Liversidge

    IPC分类号： A61K9/48 ,  A61K9/14 ,  A61K38/13 ,  A61K9/20 ,  A61K9/10 ,  A61K9/08 ,  A61K9/12 ,  A61K33/24 ,  A61P37/02 ,  A61P37/06 ,  B82Y5/00

    CPC分类号： A61K9/5084 ,  A61K9/14 ,  A61K9/1676 ,  A61K9/5078 ,  A61K31/395

    摘要： The present invention is directed to a composition comprising a nanoparticulate cyclosporine having improved bioavailability. The nanoparticulate cyclosporine particles of the composition have an effective average particle size of less than about 2000 nm in diameter and are useful in the prevention and treatment of organ transplant rejection and autoimmune diseases such as psoriasis, rheumatoid arthritis, and other related diseases. The invention also relates to a controlled release composition comprising a cyclosporine or a nanoparticulate cyclosporine that in operation delivers the drug in a pulsed or bimodal manner for the prevention and treatment of organ transplant rejection and autoimmune diseases such as psoriasis, rheumatoid arthritis, and other related diseases.

    摘要翻译： 本发明涉及包含具有改善的生物利用度的纳米颗粒环孢霉素的组合物。 组合物的纳米颗粒环孢菌素颗粒具有直径小于约2000nm的有效平均粒度，并且可用于预防和治疗器官移植排斥和自身免疫性疾病如牛皮癣，类风湿性关节炎和其它相关疾病。 本发明还涉及包含环孢菌素或纳米颗粒环孢菌素的控释组合物，其在操作中以脉冲或双峰方式递送药物以预防和治疗器官移植排斥和自身免疫性疾病如牛皮癣，类风湿性关节炎和其它相关的 疾病

    Nanoparticulate and controlled release compositions comprising cyclosporine
    7.
    发明授权
    Nanoparticulate and controlled release compositions comprising cyclosporine 失效
    包含环孢菌素的纳米颗粒和控释组合物

    公开(公告)号：US07825087B2

    公开(公告)日：2010-11-02

    申请号：US11568692

    申请日：2006-04-12

    申请人： Scott A. Jenkins ,  Gary Liversidge

    发明人： Scott A. Jenkins ,  Gary Liversidge

    IPC分类号： A61K38/12 ,  A61K51/08

    CPC分类号： A61K9/5084 ,  A61K9/14 ,  A61K9/1676 ,  A61K9/5078 ,  A61K31/395

    摘要： The present invention is directed to a composition comprising a nanoparticulate cyclosporine having improved bioavailability. The nanoparticulate cyclosporine particles of the composition have an effective average particle size of less than about 2000 nm in diameter and are useful in the prevention and treatment of organ transplant rejection and autoimmune diseases such as psoriasis, rheumatoid arthritis, and other related diseases. The invention also relates to a controlled release composition comprising a cyclosporine or a nanoparticulate cyclosporine that in operation delivers the drug in a pulsed or bimodal manner for the prevention and treatment of organ transplant rejection and autoimmune diseases such as psoriasis, rheumatoid arthritis, and other related diseases.

    摘要翻译： 本发明涉及包含具有改善的生物利用度的纳米颗粒环孢霉素的组合物。 组合物的纳米颗粒环孢菌素颗粒具有直径小于约2000nm的有效平均粒度，并且可用于预防和治疗器官移植排斥和自身免疫性疾病如牛皮癣，类风湿性关节炎和其它相关疾病。 本发明还涉及包含环孢菌素或纳米颗粒环孢菌素的控释组合物，其在操作中以脉冲或双峰方式递送药物以预防和治疗器官移植排斥和自身免疫性疾病如牛皮癣，类风湿性关节炎和其它相关的 疾病