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公开(公告)号：US09451897B2
公开(公告)日：2016-09-27
申请号：US12958910
申请日：2010-12-02
IPC分类号： A61B5/04 , A61B5/0408 , A61B5/0432 , A61B5/00
CPC分类号： A61B5/04087 , A61B5/0006 , A61B5/04085 , A61B5/04325 , A61B5/6833 , A61B2560/0412 , Y10T29/49117
摘要： In one configuration, an adherent device to adhere to a skin of a subject includes a stretchable base layer having an upper side and a lower side and an adhesive coating on the lower side to adhere the base layer to the skin of the subject. The base layer has at least two openings extending therethrough, each of the at least two openings having a size. The adherent device also includes a stretchable covering layer positioned above and adhered to the base layer with an adhesive to define at least two pockets. The adherent device also includes at least two gels, each gel having a size larger than the size of openings to retain the gel substantially within the pocket, and a circuit carrier supported with the stretchable base layer to measure at least one physiologic signal of the subject. Other configurations and methods are also claimed.
摘要翻译： 在一种构造中，粘附到受试者的皮肤上的粘附装置包括具有上侧和下侧的可拉伸基底层和在下侧上的粘合剂涂层，以将基底层粘附到受试者的皮肤上。 基层具有延伸穿过其中的至少两个开口，所述至少两个开口中的每一个具有尺寸。 粘附装置还包括可伸缩的覆盖层，该层可以用粘合剂定位在基底层上方并粘附到基底层上，以限定至少两个口袋。 粘附装置还包括至少两个凝胶，每个凝胶具有大于开口尺寸的尺寸，以将凝胶基本保持在口袋内;以及电路载体，其被可拉伸基底层支撑以测量受试者的至少一个生理信号 。 还要求保护其它配置和方法。
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公开(公告)号：US20160249817A1
公开(公告)日：2016-09-01
申请号：US15009307
申请日：2016-01-28
IPC分类号： A61B5/0215 , A61B5/05 , A61B5/00 , A61B5/026
CPC分类号： A61B5/0215 , A61B5/02141 , A61B5/026 , A61B5/05 , A61B5/6851 , A61B2562/0247 , A61M2025/09083
摘要： A high performance guide wire with a pressure sensor for measuring blood pressure, may utilize a single electrical lead connected to the guide wire. An integrated circuit, powered by the single electrical connection on the guide wire, may interface with the pressure sensor, and may convert pressure information to an encoded signal. The encoded signal may be detectable in the electrical circuit, and can be used to display a pressure waveform as detected by the pressure sensor. For example, when utilized for percutaneous coronary interventions, such a guide wire can provide high quality blood pressure measurements (e.g., for fractional flow reserve), while also possessing excellent steerability and handling characteristics for navigating tortuous anatomy.
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公开(公告)号：US08823490B2
公开(公告)日：2014-09-02
申请号：US13139996
申请日：2009-12-15
申请人： Imad Libbus , Badri Amurthur , Yatheendhar D. Manicka , Scott T. Mazar , Matt Merkert , Brett A. Landrum
发明人： Imad Libbus , Badri Amurthur , Yatheendhar D. Manicka , Scott T. Mazar , Matt Merkert , Brett A. Landrum
IPC分类号： G08B25/00
CPC分类号： A61B5/0002 , A61B5/0006 , A61B5/002 , A61B5/01 , A61B5/02055 , A61B5/04085 , A61B5/0537 , A61B5/085 , A61B5/1115 , A61B5/1117 , A61B5/1455 , A61B5/4818 , A61B5/6833 , A61B2562/0219 , G06F19/00 , G06Q50/22 , Y10S128/903
摘要： An adherent patient device is configured to adhere to the skin of the patient and measure electrocardiogram data, impedance data, accelerometer data, blood oxygen data and temperature data. The adherent device can communicate wirelessly with gateways and a local processor system, such that the patient can wander about the hospital and update the monitoring station with the patient data when the patient is ambulatory. The local processor system can be configured to customize alerts for the patient, for example to notify automatically a specialist in response to a special condition of the patient. The adherent device may comprise a unique adherent device identifier such that the customized alert can be sent based on the unique device identifier. Each of the gateways can be carried and may comprise a unique gateway identifier, such that the unique device identifier and the unique gateway identifier can be used to locate the ambulatory patient.
摘要翻译： 附着的患者装置被配置为粘附到患者的皮肤并测量心电图数据，阻抗数据，加速度计数据，血氧数据和温度数据。 附着设备可以与网关和本地处理器系统进行无线通信，使得当患者走动时，患者可以在医院周围漫游并且利用患者数据更新监测站。 本地处理器系统可以被配置为为患者定制警报，例如，以响应患者的特殊状况自动通知专家。 附着设备可以包括唯一的附着设备标识符，使得可以基于唯一的设备标识符来发送定制的警报。 可以携带每个网关，并且可以包括唯一的网关标识符，使得可以使用唯一的设备标识符和唯一的网关标识符来定位移动患者。
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公开(公告)号：US08718752B2
公开(公告)日：2014-05-06
申请号：US12402318
申请日：2009-03-11
CPC分类号： A61B5/7275 , A61B5/0006 , A61B5/0022 , A61B5/0031 , A61B5/0205 , A61B5/02055 , A61B5/04085 , A61B5/046 , A61B5/0464 , A61B5/053 , A61B5/6833 , A61B5/7246 , A61B7/04 , A61B2560/0412 , G06F19/00
摘要： Systems and methods of detecting an impending cardiac decompensation of a patient measure an electrocardiogram signal of the patient. An incidence of cardiac arrhythmias is determined from the electrocardiogram signal. A risk of impending decompensation is determined in response to the incidence of cardiac arrhythmias. In many embodiments, the impending decompensation can be detected early enough to avoid, or at least delay, the impending decompensation, such that patient trauma and/or expensive ICU care can be avoided. Although embodiments make specific reference to monitoring electrocardiogram and other physiological signals with an adherent patch, the system methods and devices are applicable to many applications in which physiological monitoring is used, for example wireless physiological monitoring with implanted sensors for extended periods.
摘要翻译： 检测患者即将到来的心脏代偿失调的系统和方法测量患者的心电图信号。 由心电图信号确定心律失常的发生率。 随着心律失常的发生，确定即将失代偿的风险。 在许多实施方案中，可以提前检测即将发生的代偿失调，以避免或至少延迟即将发生的代偿失调，使得可以避免患者创伤和/或昂贵的ICU护理。 尽管实施例特别参考了使用粘附贴片监测心电图和其他生理信号，但是系统方法和装置可应用于其中使用生理监测的许多应用，例如用植入式传感器进行长时间的无线生理监测。
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5.发明授权Method and apparatus for establishing context among events and optimizing implanted medical device performance 有权用于在事件之间建立上下文并优化植入的医疗设备性能的方法和装置公开(公告)号：US08694116B2
公开(公告)日：2014-04-08
申请号：US13447816
申请日：2012-04-16
申请人： Bruce H. KenKnight , Eric G. Lovett , Robert J. Sweeney , Scott T. Mazar , Yatheendhar D. Manicka
发明人： Bruce H. KenKnight , Eric G. Lovett , Robert J. Sweeney , Scott T. Mazar , Yatheendhar D. Manicka
IPC分类号： A61N1/08
CPC分类号： A61N1/36514 , A61N1/3627 , A61N1/37211 , A61N1/37235 , A61N1/37282 , G06F19/00
摘要： An apparatus and method for adjusting the performance of an implanted device based on data including contextual information. Contextual information, including operational and performance data concerning the implanted device as well as the patient with the implanted device, is stored by a portable electronic device. In one embodiment, the portable electronic device is adapted for battery operation and includes a personal digital assistant (PDA). The portable electronic device is adapted for use as an interface to conduct wireless communications with the implanted device. In one embodiment, the portable electronic device interfaces with a clinical programmer for use by a physician.
摘要翻译： 一种用于基于包括上下文信息的数据来调整植入装置的性能的装置和方法。 上下文信息，包括关于植入装置的操作和性能数据以及具有植入装置的患者，由便携式电子装置存储。 在一个实施例中，便携式电子设备适用于电池操作并且包括个人数字助理（PDA）。 便携式电子设备适于用作与植入的设备进行无线通信的接口。 在一个实施例中，便携式电子设备与临床程序员接口以供医生使用。
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公开(公告)号：US20120022609A1
公开(公告)日：2012-01-26
申请号：US13251748
申请日：2011-10-03
IPC分类号： A61N1/372
CPC分类号： A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要： Devices, systems and methods for nerve stimulation for OSA therapy.
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公开(公告)号：US20120010532A1
公开(公告)日：2012-01-12
申请号：US12980774
申请日：2010-12-29
CPC分类号： A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要： Devices, systems and methods for nerve stimulation for OSA therapy.
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8.发明授权System and method for correlating biometric trends with a related temporal event 有权将生物识别趋势与相关时间事件相关联的系统和方法公开(公告)号：US08054178B2
公开(公告)日：2011-11-08
申请号：US12476833
申请日：2009-06-02
申请人： Scott T. Mazar , Bruce H. KenKnight
发明人： Scott T. Mazar , Bruce H. KenKnight
CPC分类号： A61B5/0002 , G06F19/00 , G06Q50/22
摘要： Systems and methods for correlating biometric trends with a related temporal event are disclosed. A preferred embodiment utilizes an implantable medical device comprising at least one sensor in electronic communication with a patient management system adapted to temporally analyze and correlate biometric data. Some embodiments of a system disclosed herein also can be configured as an Advanced Patient Management system that helps better monitor, predict and manage chronic diseases.
摘要翻译： 公开了将生物识别趋势与相关时间事件相关联的系统和方法。 优选实施例利用可植入医疗装置，其包括至少一个传感器，该传感器与患者管理系统进行电子通信，患者管理系统适于暂时分析和关联生物特征数据。 本文公开的系统的一些实施例还可以被配置为有助于更好地监测，预测和管理慢性疾病的高级患者管理系统。
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9.发明授权Repeater providing data exchange with a medical device for remote patient care and method thereof 有权中继器提供与用于远程病人护理的医疗设备的数据交换及其方法公开(公告)号：US07791467B2
公开(公告)日：2010-09-07
申请号：US11872841
申请日：2007-10-16
IPC分类号： G08B1/00
CPC分类号： A61B5/0022 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/0809 , A61B5/14532 , A61B5/4839 , A61B5/747 , A61B2560/0209 , A61B2560/0271 , A61B2560/045 , G06F19/00 , G06F19/3418 , G06Q50/22 , G06Q50/24 , G16H10/60 , G16H40/63 , G16H50/20 , G16H50/80
摘要： A repeater providing data exchange with a medical device for remote patient care and method thereof are provided. A plurality of interfaces include a medical device interface interconnected with a medical device, a wireless interface coupled to a wireless medium, and a wired interface coupled to a wired medium. An interface selector includes a test module operable over the wireless interface and the wired interface to evaluate conditions on each respective medium that could affect data exchange over each of the interfaces. The interface selector further includes a selection module specifying data exchange to occur using one of the wireless interface and the wired interface based on the evaluated conditions. An interrogator module exchanges data with the medical device over the medical device interface. A data transfer module exchanges the data with an external device over the specified interface.
摘要翻译： 提供了一种与用于远程病人护理的医疗设备进行数据交换的中继器及其方法。 多个接口包括与医疗设备互连的医疗设备接口，耦合到无线介质的无线接口以及耦合到有线介质的有线接口。 接口选择器包括可在无线接口和有线接口上操作的测试模块，以评估可能影响每个接口上的数据交换的每个相应介质上的条件。 接口选择器还包括基于所评估的条件指定要使用无线接口和有线接口之一发生的数据交换的选择模块。 询问器模块通过医疗设备接口与医疗设备交换数据。 数据传输模块通过指定的接口与外部设备交换数据。
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10.发明申请METHODS AND APPARATUSES FOR IMPLANTABLE MEDICAL DEVICE TELEMETRY POWER MANAGEMENT 有权用于可植入医疗设备电话管理的方法和装置公开(公告)号：US20100114233A1
公开(公告)日：2010-05-06
申请号：US12684303
申请日：2010-01-08
IPC分类号： A61N1/08
CPC分类号： A61N1/37 , A61N1/08 , A61N1/37223 , A61N1/37276 , A61N1/3925 , A61N1/3962 , G06F19/00 , G06F19/3418
摘要： A method comprises connecting at least one portion of a far-field radio-frequency (RF) first telemetry circuit in an implantable medical device to an energy source through a power connection module, detecting information included in a first predetermined wireless signal, changing a conductivity state of the power connection module when the information in the first predetermined wireless signal is detected to couple power to the at least one portion of the first telemetry circuit, detecting a second predetermined wireless signal, and changing a conductivity state of the power connection module to decouple power to the at least one portion of the first telemetry circuit when the second predetermined wireless signal is detected and the first telemetry circuit enters an idle state.
摘要翻译： 一种方法包括通过电力连接模块将可植入医疗装置中的远场射频（RF）第一遥测电路的至少一部分连接到能量源，检测包括在第一预定无线信号中的信息，改变电导率 当检测到第一预定无线信号中的信息以将功率耦合到第一遥测电路的至少一部分时，检测第二预定无线信号，并将电力连接模块的导电状态改变为 当检测到第二预定无线信号并且第一遥测电路进入空闲状态时，将功率去耦到第一遥测电路的至少一部分。
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