公开(公告)号：US09315416B2

公开(公告)日：2016-04-19

申请号：US13137150

申请日：2011-07-22

申请人： Seiji Yamaguchi ,  Koji Tasumi ,  Hiroyuki Tajima ,  Satoshi Wada ,  Miki Moriyama ,  Kazuya Aida ,  Hiroki Watanabe

发明人： Seiji Yamaguchi ,  Koji Tasumi ,  Hiroyuki Tajima ,  Satoshi Wada ,  Miki Moriyama ,  Kazuya Aida ,  Hiroki Watanabe

IPC分类号： C03C27/00 ,  H01L33/56

CPC分类号： C03C27/00 ,  H01L33/56 ,  H01L2224/13 ,  H01L2933/005

摘要： A method of manufacturing a light-emitting device including a light-emitting element mounted on a substrate and sealed with a glass. The method includes heating the glass by a first mold that is heated to a temperature higher than a yield point of the glass, the glass contacting the first mold, and pressing the glass against the light-emitting element mounted on the substrate supported by a second mold to seal the light-emitting element with the glass.

摘要翻译： 一种制造包括安装在基板上并用玻璃密封的发光元件的发光装置的方法。 该方法包括通过加热至高于玻璃的屈服点的温度的第一模具加热玻璃，玻璃与第一模具接触，并将玻璃压靠在安装在基板上的发光元件上，第二模具由第二模具 模具用玻璃密封发光元件。

公开(公告)号：US08691208B2

公开(公告)日：2014-04-08

申请号：US13071445

申请日：2011-03-24

申请人： Shunji Tomatsu ,  William Sly ,  Jeffrey Grubb ,  Tatsuo Nishioka ,  Ken-ichi Miyamoto ,  Seiji Yamaguchi

发明人： Shunji Tomatsu ,  William Sly ,  Jeffrey Grubb ,  Tatsuo Nishioka ,  Ken-ichi Miyamoto ,  Seiji Yamaguchi

IPC分类号： A61K35/12 ,  A61K48/00 ,  C12N5/14 ,  C12N15/52

CPC分类号： A61K38/465 ,  C12Y301/03001

摘要： The present invention provides compositions and methods for use in enzyme replacement therapy. The inventors disclose a method of producing membrane bound enzymes in an active soluble form by eliminating the glycosylphosphatidylinositol (GPI) membrane anchor. In particular the inventors disclose a soluble active form of the membrane bound enzyme TNSALP which they produced by deleting the GPI anchor single peptide sequence. They have further shown that this composition is useful for treatment of hypophosphatasia. The inventors also disclose oligo acid amino acid variants thereof which specifically target bone tissue.

摘要翻译： 本发明提供了用于酶替代疗法的组合物和方法。 本发明人公开了通过消除糖基磷脂酰肌醇（GPI）膜锚定点来生产活性可溶形式的膜结合酶的方法。 特别地，本发明人公开了通过缺失GPI锚单肽序列产生的膜结合酶TNSALP的可溶性活性形式。 他们进一步表明，该组合物可用于治疗下尿失禁。 本发明人还公开了特异性靶向骨组织的寡糖氨基酸变体。

公开(公告)号：US20120067085A1

公开(公告)日：2012-03-22

申请号：US13137150

申请日：2011-07-22

申请人： Seiji Yamaguchi ,  Koji Tasumi ,  Hiroyuki Tajima ,  Satoshi Wada ,  Miki Moriyama ,  Kazuya Aida ,  Hiroki Watanabe

发明人： Seiji Yamaguchi ,  Koji Tasumi ,  Hiroyuki Tajima ,  Satoshi Wada ,  Miki Moriyama ,  Kazuya Aida ,  Hiroki Watanabe

IPC分类号： C03B23/20

CPC分类号： C03C27/00 ,  H01L33/56 ,  H01L2224/13 ,  H01L2933/005

摘要： A method of manufacturing a light-emitting device including a light-emitting element mounted on a substrate and sealed with a glass. The method includes heating the glass by a first mold that is heated to a temperature higher than a yield point of the glass, the glass contacting the first mold, and pressing the glass against the light-emitting element mounted on the substrate supported by a second mold to seal the light-emitting element with the glass.

摘要翻译： 一种制造包括安装在基板上并用玻璃密封的发光元件的发光装置的方法。 该方法包括通过加热至高于玻璃的屈服点的温度的第一模具加热玻璃，玻璃与第一模具接触，并将玻璃压靠在安装在基板上的发光元件上，第二模具由第二模具 模具用玻璃密封发光元件。

公开(公告)号：US20110273851A1

公开(公告)日：2011-11-10

申请号：US13145289

申请日：2009-11-06

申请人： Seiji Yamaguchi

发明人： Seiji Yamaguchi

IPC分类号： H05K7/00

CPC分类号： H05K1/141 ,  H01L21/56 ,  H01L23/13 ,  H01L23/3121 ,  H01L2224/16225 ,  H01L2224/32225 ,  H01L2224/73204 ,  H01L2924/15151 ,  H01L2924/15153 ,  H05K1/183 ,  H05K3/281 ,  H05K3/284 ,  H05K2201/09072 ,  H05K2201/10477 ,  H01L2924/00

摘要： A circuit board includes a substrate having a first surface and a second surface on an opposite side of the first surface. A hole is provided in the substrate so as to penetrate from the first surface to the second surface. A recess portion is formed in the second surface and has a bottom larger than a cross-section area of the hole. The hole is exposed on the bottom of the recess portion.

摘要翻译： 电路板包括具有在第一表面的相对侧上的第一表面和第二表面的基底。 在基板上设置有从第一表面到第二表面的孔。 在第二表面上形成凹部，其底部大于孔的截面积。 孔露出在凹部的底部。

公开(公告)号：US20110082562A1

公开(公告)日：2011-04-07

申请号：US12995850

申请日：2009-06-01

申请人： Tadashi Kokubo ,  Takashi Kizuki ,  Seiji Yamaguchi ,  Tomiharu Matsushita

发明人： Tadashi Kokubo ,  Takashi Kizuki ,  Seiji Yamaguchi ,  Tomiharu Matsushita

IPC分类号： A61F2/28 ,  B05D3/02

CPC分类号： A61L27/06 ,  A61F2/30767 ,  A61F2310/00023 ,  A61L27/30 ,  A61L2430/02

摘要： A bone repair material being superior in apatite-forming ability and its stability in a storage and high in scratch resistance is disclosed. The material is produced by a method comprising the steps of: immersing a substrate made of titanium or a titanium alloy in a first aqueous solution that does not contain calcium ions but contains at least one cation selected from the group consisting of sodium ions and potassium ions and is alkaline; immersing the substrate in a second aqueous solution that does not contain phosphate ions but contains calcium ions; heating the substrate in a dry atmosphere; and treating the substrate with hot water of 60° C. or higher or with steam.

摘要翻译： 公开了一种磷灰石形成能力优异的骨修复材料及其在储存中的稳定性和高耐擦伤性。 该材料通过以下方法制造：将由钛或钛合金制成的基材浸渍在不含钙离子的第一水溶液中，但含有选自钠离子和钾离子中的至少一种阳离子 碱性; 将基板浸入不含磷酸根离子但含有钙离子的第二水溶液中; 在干燥的气氛中加热基材; 用60℃以上的热水或蒸汽处理基板。

公开(公告)号：US20100099953A1

公开(公告)日：2010-04-22

申请号：US12644198

申请日：2009-12-22

申请人： Akira SUZUKI ,  Fumiyuki ONODA ,  Katsuyuki SAITO ,  Seiji YAMAGUCHI ,  Kiyoshi MIYAKE ,  Hitoshi SHIRAI

发明人： Akira SUZUKI ,  Fumiyuki ONODA ,  Katsuyuki SAITO ,  Seiji YAMAGUCHI ,  Kiyoshi MIYAKE ,  Hitoshi SHIRAI

IPC分类号： A61B1/00

CPC分类号： A61B1/015 ,  A61B1/00068

摘要： A medical device includes a communication member including a first opening portion, a second opening portion, and a communication conduit for communication between the first opening portion and the second opening portion, a closing portion capable of liquid-tightly closing the communication conduit, and a maintaining member capable of maintaining the closing portion in a closed state.

摘要翻译： 医疗装置包括：连通构件，包括第一开口部分，第二开口部分和用于在第一开口部分和第二开口部分之间连通的连通管道，能够液密地闭合连通管道的封闭部分，以及 保持构件能够将封闭部分保持在关闭状态。

公开(公告)号：US07701481B2

公开(公告)日：2010-04-20

申请号：US10852810

申请日：2004-05-25

申请人： Katsuya Mizukami ,  Seiji Yamaguchi

发明人： Katsuya Mizukami ,  Seiji Yamaguchi

IPC分类号： H04N7/12

CPC分类号： G03B27/323 ,  G03B15/03 ,  H04N5/2256 ,  H04N5/232 ,  H04N5/23296

摘要： A video magnifier includes a body including a base, a table on which an object to be read is placed, the table being disposed on the base, a video camera disposed over the table, an illumination lamp illuminating the object placed on the table and a pointer irradiating a part of the object photographed by the video camera, and a monitor television displaying a video image delivered from the video camera. In the video magnifier, in synchronization with irradiation of the photographed part of the object by the pointer, an illuminance of the illumination lamp is rendered lower than an illuminance of the pointer.

摘要翻译： 视频放大器包括：主体，其包括基座，待放置对象的表，放置在基座上的桌子，设置在桌子上的摄像机，照亮放置在桌子上的物体的照明灯; 照射由摄像机拍摄的物体的一部分的指针，以及显示从摄像机传送的视频图像的监视器电视。 在视频放大器中，与通过指示物照射被摄体的拍摄部分同步，使照明灯的照度低于指示体的照度。

公开(公告)号：US07665385B2

公开(公告)日：2010-02-23

申请号：US10978677

申请日：2004-11-02

申请人： Kenichi Misaki ,  Masamoto Ito ,  Kenji Nakamura ,  Seiji Yamaguchi

发明人： Kenichi Misaki ,  Masamoto Ito ,  Kenji Nakamura ,  Seiji Yamaguchi

IPC分类号： G05G1/44

CPC分类号： G05G1/30 ,  B60T7/02 ,  B62L3/04 ,  Y10T74/20528 ,  Y10T74/20888

摘要： To reduce moment generated at the proximal portion and the supporting portion of a brake pedal and to prevent an increase in weight even when the brake pedal is disposed outside a vehicle body and an operating unit is disposed away from the brake pedal within the vehicle body. A supporting shaft rotates integrally with the brake pedal by being connected with the brake pedal at one end with a supporting member for supporting both ends of the supporting shaft. An operating member is provided for operating an operating unit by rotation of the brake pedal and the supporting shaft by being connected to the other end of the supporting shaft at the position away from the brake pedal are provided. A pedal pad unit includes a flat depressing surface forming portion to be covered by a cover on the front face on which the driver depresses and a mounting portion extending from the depressing surface forming portion in the direction opposite from the cover for being pivotally mounted on the pedal lever unit. The depressing surface forming portion and the mounting portion are integrally formed.

摘要翻译： 为了减少在制动踏板的近端部分和支撑部分处产生的力矩，并且即使当制动踏板设置在车体外部并且操作单元远离制动踏板在车体内时也防止重量增加。 支撑轴通过与制动踏板一端连接而与制动踏板一体地旋转，支撑构件用于支撑支撑轴的两端。 提供操作构件，用于通过在远离制动踏板的位置处连接到支撑轴的另一端而通过制动踏板的旋转来操作操作单元。 脚踏板单元包括一个平面按压表面形成部分，该平坦的压下表面形成部分将被驱动器压下的前表面上的盖子覆盖;以及安装部分，该安装部件从与该盖子相反的方向从该按压表面形成部分延伸， 踏板杆单元。 压下表面形成部分和安装部分整体形成。

公开(公告)号：US07634215B2

公开(公告)日：2009-12-15

申请号：US11953150

申请日：2007-12-10

申请人： Issei Imamura ,  Seiji Yamaguchi

发明人： Issei Imamura ,  Seiji Yamaguchi

IPC分类号： G03G15/08 ,  G03G15/00 ,  G03G15/04

CPC分类号： G03G15/0822 ,  G03G2215/0827 ,  G03G2215/0838 ,  G03G2215/0852

摘要： A developing apparatus includes: an agitating chamber agitating a developer; a developing chamber provided with an inlet to which the developer is supplied from the agitating chamber and an outlet from which the developer is returned to the agitating chamber; a developer carrying member; a rotatable developer supplying member supplying the developer to the developer carrying member; a developer conveying member, provided above the center of rotation of the developer supplying member in the developing chamber, for conveying the developer in a longitudinal direction of the developer carrying member, wherein, in a vertical cross-sectional area of a region vertically above the center of rotation of the developer supplying member of the developing chamber, excluding a developer conveying region by the developer conveying member, a cross-sectional area S1 upstream in the developer conveying direction and a cross-sectional area S2 downstream in the developer conveying direction satisfy a relationship of S1

摘要翻译： 显影装置包括：搅拌室，搅拌显影剂; 显影室，其具有从搅拌室供给显影剂的入口和显影剂从该出口返回到搅拌室; 显影剂承载构件; 将显影剂供应到显影剂承载构件的可旋转显影剂供应构件; 显影剂输送构件，其设置在显影剂室中的显影剂供给构件的旋转中心的上方，用于沿着显影剂承载构件的纵向方向输送显影剂，其中，在垂直于显影剂承载构件的垂直方向上的区域的垂直横截面积中 显影剂输送区域除了显影剂输送区域以外，显影剂输送方向的显影剂输送区域除了显影剂输送方向上游的截面积S1和显影剂输送方向下游的截面积S2的显影室供给构件的旋转中心满足 S1

公开(公告)号：US07583916B2

公开(公告)日：2009-09-01

申请号：US10988703

申请日：2004-11-16

申请人： Hiroaki Ogata ,  Syuhei Kawasaki ,  Seiji Yamaguchi ,  Shinji Uehara

发明人： Hiroaki Ogata ,  Syuhei Kawasaki ,  Seiji Yamaguchi ,  Shinji Uehara

IPC分类号： G03G15/08

CPC分类号： G03G15/0856 ,  G03G15/086 ,  G03G15/0889 ,  G03G2215/0685 ,  G03G2215/085

摘要： An image forming apparatus includes an image bearing member; a developing device including a carrying member for carrying a one component developer and for developing an electrostatic image formed on the image bearing member with the developer; a rotatable developer supplying device, contacted to the carrying member, for supplying the developer to the carrying member; a developer regulating device for regulating an amount of the developer carried on the carrying member; a developer stirring device for stirring the developer a developer supply device for supplying the developer to the developing device; and a controller for controlling supply of the developer to the developing device from the developer supply device. A lower end of the developer stirring device is disposed at a position which is vertically above an upper end of the developer supplying device and which is vertically above a contact portion between the carrying member and the developer regulating device. A direction of rotation of the developer supplying device is such that the developer supplying device is contacted to the carrying member during a downward part of the rotation of the developer supplying device. The controller controls the developer supply device such that a lower limit of a height of a surface of the developer is vertically above a lower end of the developer stirring device and an upper limit of the height of the surface of the developer is vertically below a wall of an upper surface of the developing device.

摘要翻译： 图像形成装置包括：图像承载部件; 显影装置，其包括用于承载单组分显影剂的承载构件，并用显影剂使形成在图像承载构件上的静电图像显影; 可转动的显影剂供应装置，与所述承载构件接触，用于将所述显影剂供应到所述承载构件; 显影剂调节装置，用于调节承载构件上承载的显影剂的量; 显影剂搅拌装置，用于搅拌显影剂用于向显影装置供应显影剂的显影剂供应装置; 以及用于控制从显影剂供应装置向显影装置供应显影剂的控制器。 显影剂搅拌装置的下端设置在垂直于显影剂供给装置的上端上方并位于承载构件和显影剂调节装置之间的接触部分上方的位置。 显影剂供给装置的旋转方向是这样的：显影剂供给装置在显影剂供应装置的旋转的向下部分期间与承载构件接触。 控制器控制显影剂供应装置，使得显影剂表面的高度的下限垂直于显影剂搅拌装置的下端，并且显影剂表面的高度的上限垂直地低于壁 的显影装置的上表面。