公开(公告)号：US07745203B2

公开(公告)日：2010-06-29

申请号：US11045646

申请日：2005-01-31

申请人： Sadato Hongo ,  Minoru Ishikawa ,  Takiji Ishimura ,  Shigeru Wakayama ,  Shinji Yanaga ,  Kenji Oki ,  Jun Okada

发明人： Sadato Hongo ,  Minoru Ishikawa ,  Takiji Ishimura ,  Shigeru Wakayama ,  Shinji Yanaga ,  Kenji Oki ,  Jun Okada

IPC分类号： C12M1/00 ,  C12M1/34 ,  C12M3/00

CPC分类号： G01N33/5438

摘要： A base sequence detection apparatus is provided with a channel formed on a base sequence detection chip. Working electrodes are formed along the channel and include a probe immobilized thereon, counter electrodes are formed on the inner surface of the channel and, reference electrodes are formed on the inner surface of the channel. An introduction port introduces solution or air from the upstream side of the channel, a delivery port delivers the solution or air in the channel, and the sample is injected into the channel through a sample injection port.

摘要翻译： 碱基序列检测装置具有形成在基序列检测芯片上的信道。 沿通道形成工作电极，并且包括固定在其上的探针，在通道的内表面上形成相对电极，并且在通道的内表面上形成参考电极。 引入端口从通道的上游侧引入溶液或空气，输送口将溶液或空气输送到通道中，并且样品通过样品注入口注入通道。

公开(公告)号：US20100121490A1

公开(公告)日：2010-05-13

申请号：US12689716

申请日：2010-01-19

申请人： Sadato HONGO ,  Minoru ISHIKAWA ,  Takiji ISHIMURA ,  Shigeru WAKAYAMA ,  Shinji YANAGA ,  Kenji OKI ,  Jun OKADA

发明人： Sadato HONGO ,  Minoru ISHIKAWA ,  Takiji ISHIMURA ,  Shigeru WAKAYAMA ,  Shinji YANAGA ,  Kenji OKI ,  Jun OKADA

IPC分类号： G05B21/00 ,  G01N27/26

CPC分类号： G01N33/5438

摘要： A base sequence detection apparatus is provided with a channel formed on a base sequence detection chip. Working electrodes are formed along the channel and include a probe immobilized thereon, counter electrodes are formed on the inner surface of the channel and, reference electrodes are formed on the inner surface of the channel. An introduction port introduces solution or air from the upstream side of the channel, a delivery port delivers the solution or air in the channel, and the sample is injected into the channel through a sample injection port.

摘要翻译： 碱基序列检测装置具有形成在基序列检测芯片上的信道。 沿通道形成工作电极，并且包括固定在其上的探针，在通道的内表面上形成相对电极，并且在通道的内表面上形成参考电极。 引入端口从通道的上游侧引入溶液或空气，输送口将溶液或空气输送到通道中，并且样品通过样品注入口注入通道。

公开(公告)号：US20050158787A1

公开(公告)日：2005-07-21

申请号：US11045646

申请日：2005-01-31

申请人： Sadato Hongo ,  Minoru Ishikawa ,  Takiji Ishimura ,  Shigeru Wakayama ,  Shinji Yanaga ,  Kenji Oki ,  Jun Okada

发明人： Sadato Hongo ,  Minoru Ishikawa ,  Takiji Ishimura ,  Shigeru Wakayama ,  Shinji Yanaga ,  Kenji Oki ,  Jun Okada

IPC分类号： C12M1/34 ,  C12Q1/68 ,  G01N33/543

CPC分类号： G01N33/5438

摘要： A base sequence detection apparatus is provided with a channel formed on a base sequence detection chip. Working electrodes are formed along the channel and include a probe immobilized thereon, counter electrodes are formed on the inner surface of the channel and, reference electrodes are formed on the inner surface of the channel. An introduction port introduces solution or air from the upstream side of the channel, a delivery port delivers the solution or air in the channel, and the sample is injected into the channel through a sample injection port.

摘要翻译： 碱基序列检测装置具有形成在基序列检测芯片上的信道。 沿通道形成工作电极，并且包括固定在其上的探针，在通道的内表面上形成相对电极，并且在通道的内表面上形成参考电极。 引入端口从通道的上游侧引入溶液或空气，输送口将溶液或空气输送到通道中，并且样品通过样品注入口注入通道。

公开(公告)号：US4987851A

公开(公告)日：1991-01-29

申请号：US292314

申请日：1988-12-30

申请人： Satoshi Yasuda ,  Shigeru Wakayama ,  Yoshiaki Tsukumo ,  Takashi Haraguchi ,  Syun Egusa

发明人： Satoshi Yasuda ,  Shigeru Wakayama ,  Yoshiaki Tsukumo ,  Takashi Haraguchi ,  Syun Egusa

IPC分类号： B05D1/20

CPC分类号： B82Y30/00 ,  B05D1/206 ,  B82Y40/00

摘要： An organic film forming apparatus includes a trough storing water therein and a work drive device for moving a work with respect to the trough. The surface of the water is partitioned by a rod into a first developing region on which a monomolecular film is developed and a second developing region on which no monomolecular film is developed. The work is moved by the device through the developed monomolecular film so as to adhere the film on the surface of the work. The device has a holding mechanism which has a holding portion engaged with the work, and which holds the work so that when the work passes through the developed monomolecular film, the holding portion is away from the film or passes through the film after almost the entire work passes through the film.

公开(公告)号：US5006374A

公开(公告)日：1991-04-09

申请号：US354354

申请日：1989-05-19

申请人： Shigeru Wakayama ,  Akira Miura

发明人： Shigeru Wakayama ,  Akira Miura

IPC分类号： B05C3/10 ,  B05C3/109 ,  B05C11/11 ,  B05D1/20

CPC分类号： B82Y30/00 ,  B05C11/11 ,  B05C3/10 ,  B05C3/109 ,  B05D1/206 ,  B82Y40/00

摘要： An apparatus for forming thin organic films includes a plurality of water tanks each containing water. Monomolecular films of different amphiphatic organic molecules are developed on the surface of the liquid in water tanks, respectively. A work is dipped into and drawn up from a desired water tank, by a driving device, in a direction substantially perpendicular to the liquid surface, so that the monomolecular film in the water tank is adhered on a work surface. The work is transported by a transporting device to a position above another water tank, through an area lying above the water tanks. Then, the work is dipped into and drawn up from the other water tank, by the driving device, in a direction substantially perpendicular to the monomolecular film, so that another monomolecular film is adhered on the monomolecular film already formed on the work surface.

公开(公告)号：US20080060940A1

公开(公告)日：2008-03-13

申请号：US11980409

申请日：2007-10-31

申请人： Sadato Hongo ,  Minoru Ishikawa ,  Takiji Ishimura ,  Shigeru Wakayama ,  Shinji Yanaga ,  Kenji Oki ,  Jun Okada

发明人： Sadato Hongo ,  Minoru Ishikawa ,  Takiji Ishimura ,  Shigeru Wakayama ,  Shinji Yanaga ,  Kenji Oki ,  Jun Okada

IPC分类号： G01N27/416

CPC分类号： G01N33/5438

摘要： A base sequence detection apparatus is provided with a channel formed on a base sequence detection chip. Working electrodes are formed along the channel and include a probe immobilized thereon, counter electrodes are formed on the inner surface of the channel and, reference electrodes are formed on the inner surface of the channel. An introduction port introduces solution or air from the upstream side of the channel, a delivery port delivers the solution or air in the channel, and the sample is injected into the channel through a sample injection port.

摘要翻译： 碱基序列检测装置具有形成在基序列检测芯片上的信道。 沿通道形成工作电极，并且包括固定在其上的探针，在通道的内表面上形成相对电极，并且在通道的内表面上形成参考电极。 引入端口从通道的上游侧引入溶液或空气，输送口将溶液或空气输送到通道中，并且样品通过样品注入口注入通道。

公开(公告)号：US5929452A

公开(公告)日：1999-07-27

申请号：US42809

申请日：1998-03-17

申请人： Shusuke Yoshitake ,  Hiroaki Hirazawa ,  Shigeru Wakayama

发明人： Shusuke Yoshitake ,  Hiroaki Hirazawa ,  Shigeru Wakayama

IPC分类号： H01J9/14 ,  H01J37/147 ,  H01J37/305 ,  H01L21/027

CPC分类号： H01J37/3174 ,  B82Y10/00 ,  B82Y40/00 ,  H01J37/1477 ,  H01J2237/1516

摘要： A method of manufacturing an electrostatic deflecting electrode unit for use in charged beam lithography apparatus comprises a first step of preparing a hollow cylindrical member made of metal, a second step of forming grooves of a predetermined width in a cylindrical member in the direction of radius thereof and along lines that equally divides the periphery of the cylindrical member into eight sections, a third step of attaching a ring-like member made of an insulating material to each of end surfaces of the cylindrical member which are opposed to each other in the direction of axis of the cylindrical member in such a way that bottom portions of the grooves are exposed, and a fourth step of dividing the cylindrical member into eight electrodes by extending the bottom portions of the grooves in the direction of radius of the cylindrical member to reach the hole of the cylindrical member with the ring-like members attached. The dimensional precision of the electrostatic deflecting electrode is determined by the precision of the cylindrical member. Thus, the deflecting electrode unit is easy to process and assemble with precision.

摘要翻译： 一种制造用于带电光束光刻设备的静电偏转电极单元的方法包括：制备由金属制成的中空圆柱形构件的第一步骤，在圆柱形构件的半径方向上形成具有预定宽度的槽的第二步骤 并且沿着将圆柱形构件的周边等分成八个部分的线，第三步骤是将由绝缘材料制成的环形构件连接到圆柱形构件的每个端面上，该圆柱形构件彼此相对的方向 圆柱形构件的轴线以这样的方式使得凹槽的底部暴露;以及第四步骤，通过沿着圆柱形构件的半径方向延伸凹槽的底部，将圆柱形构件分成八个电极，以达到 圆柱形构件的孔与所述环状构件相连。 静电偏转电极的尺寸精度由圆柱形构件的精度决定。 因此，偏转电极单元易于精加工和组装。

公开(公告)号：US4848270A

公开(公告)日：1989-07-18

申请号：US126929

申请日：1987-11-30

申请人： Shigeru Wakayama ,  Akira Miura

发明人： Shigeru Wakayama ,  Akira Miura

IPC分类号： B05C3/10 ,  B05C3/109 ,  B05C11/11 ,  B05D1/20

CPC分类号： B82Y30/00 ,  B05C11/11 ,  B05C3/10 ,  B05C3/109 ,  B05D1/206 ,  B82Y40/00

摘要： An apparatus for forming thin organic films includes a plurality of water tanks each containing water. Monomolecular films of different amphiphatic organic molecules are developed on the surfaces of the liquid in water tanks, respectively. A work is dipped into and raised out of a desired water tank, by a driving device, in a direction substantially perpendicular to the liquid surface, so that the monomolecular film in the water tank is adhered on a work surface. The work is transported by a transporting device to a position above another water tank, through an area lying above the water tanks. Then, the work is dipped into and raised out of the other water tank, by the driving device, in a direction substantially perpendicular to the monomolecular film, so that another monomolecular film is adhered on the monomolecular film already formed on the work surface.