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公开(公告)号:US09868570B2
公开(公告)日:2018-01-16
申请号:US15114847
申请日:2015-02-20
申请人: Silvia Ferrari , Guglielmo Ferrari
发明人: Silvia Ferrari , Guglielmo Ferrari
CPC分类号: B65D47/0842 , B65D41/3433 , B65D47/0804 , B65D55/024 , B65D2101/0023 , B65D2101/0069
摘要: A reclosable stopper for revealing a first opening includes a base body for positioning on a container mouth (12), from which base body a pouring element extends upwardly, and a protection and closing cap integrally and hingedly connected to the base body. The base body also includes a guarantee ring connected by frangible bridges to a collar. The cap is firmly positioned on the base body for closure. A tamper-proof feature is provided between the base body having the pouring element, and the cap, for revealing a first opening, which includes a double frangible connection system which can be actuated towards the inside of the cap.
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公开(公告)号:US20160368674A1
公开(公告)日:2016-12-22
申请号:US15114847
申请日:2015-02-20
申请人: Silvia Ferrari , Guglielmo Ferrari
发明人: Silvia Ferrari , Guglielmo Ferrari
CPC分类号: B65D47/0842 , B65D41/3433 , B65D47/0804 , B65D55/024 , B65D2101/0023 , B65D2101/0069
摘要: A recloseable stopper for revealing a first opening includes a base body for positioning on a container mouth (12), from which base body a pouring element extends upwardly, and a protection and closing cap integrally and hingedly connected to the base body. The base body also includes a guarantee ring connected by frangible bridges to a collar. The cap is firmly positioned on the base body for closure. A tamper-proof feature is provided between the base body having the pouring element, and the cap, for revealing a first opening, which includes a double frangible connection system which can be actuated towards the inside of the cap.
摘要翻译: 用于露出第一开口的可重新封闭的止动件包括用于定位在容器口部(12)上的基体,倾斜元件从该基体向上延伸,以及一体地并铰接地连接到基体的保护和关闭盖。 基体还包括通过易碎桥连接到衣领的保证环。 盖子牢固地定位在基体上以封闭。 在具有倾倒元件的基体和盖之间提供防篡改特征,用于露出第一开口,该第一开口包括能够朝向盖的内部致动的双重易碎连接系统。
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3.
公开(公告)号:US20180319551A1
公开(公告)日:2018-11-08
申请号:US15959216
申请日:2018-04-21
申请人: Silvia Ferrari , Guglielmo Ferrari
发明人: Silvia Ferrari , Guglielmo Ferrari
IPC分类号: B65D41/34
CPC分类号: B65D41/34 , B65D47/0804 , B65D47/128 , B65D47/242 , B65D59/06 , B65D2101/0023 , B65D2101/003
摘要: A stopper for a container providing evidence of first opening includes an upper part with a protection cap closable on a pouring element and a ridged lower part with an upper hollow cylindrical portion disposed inside the pouring element and a lower cylindrical portion of larger diameter that is internally threaded. A frangible label is positioned between the protection cap, and a security ring is connected with the upper and lower parts with frangible bridges. An annular security crown is connected to the lower part of the stopper by frangible bridges and a cam arrangement, coaxially coupled between an outer surface of the upper hollow cylindrical portion and an inner surface of the pouring element, causes their translation and rotation. The pouring element has a duct passage and a coaxial island shutter which cooperates with a central hole in the upper hollow cylindrical portion of the lower part.
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公开(公告)号:US10906705B2
公开(公告)日:2021-02-02
申请号:US15959216
申请日:2018-04-21
申请人: Silvia Ferrari , Guglielmo Ferrari
发明人: Silvia Ferrari , Guglielmo Ferrari
摘要: A stopper for a container providing evidence of first opening includes an upper part with a protection cap closable on a pouring element and a ridged lower part with an upper hollow cylindrical portion disposed inside the pouring element and a lower cylindrical portion of larger diameter that is internally threaded. A frangible label is positioned between the protection cap, and a security ring is connected with the upper and lower parts with frangible bridges. An annular security crown is connected to the lower part of the stopper by frangible bridges and a cam arrangement, coaxially coupled between an outer surface of the upper hollow cylindrical portion and an inner surface of the pouring element, causes their translation and rotation. The pouring element has a duct passage and a coaxial island shutter which cooperates with a central hole in the upper hollow cylindrical portion of the lower part.
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公开(公告)号:US20120315650A1
公开(公告)日:2012-12-13
申请号:US13475166
申请日:2012-05-18
申请人: Silvia Ferrari , Bernadette Gruber , Barbara Plaimauer , Hanspeter Rottensteiner , Friedrich Scheiflinger
发明人: Silvia Ferrari , Bernadette Gruber , Barbara Plaimauer , Hanspeter Rottensteiner , Friedrich Scheiflinger
IPC分类号: G01N33/573
CPC分类号: G01N33/564
摘要: The present invention relates to methods and means for detecting ADAMTS13 immune complexes in a sample. The methods include the steps of capturing and labelling immune complexes of anti-ADAMTS13 antibodies. Capturing and labelling may be achieved by two different binding units targeting the immune complexes. The invention further relates to diagnosing diseases associated with immunologic ADAMTS13 dysfunction like TTP (thrombotic thrombocytopenic purpura).
摘要翻译: 本发明涉及检测样品中ADAMTS13免疫复合物的方法和手段。 所述方法包括捕获和标记抗ADAMTS13抗体的免疫复合物的步骤。 捕获和标记可以通过靶向免疫复合物的两种不同的结合单元实现。 本发明还涉及诊断与免疫学ADAMTS13功能障碍(如TTP)(血栓性血小板减少性紫癜)相关的疾病。
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