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    Methods and Apparatus for Adjusting Blood Circulation
    5.
    发明申请
    Methods and Apparatus for Adjusting Blood Circulation 有权
    调节血液循环的方法和装置

    公开(公告)号：US20080132816A1

    公开(公告)日：2008-06-05

    申请号：US11945999

    申请日：2007-11-27

    申请人： John Roy Kane ,  Scott A. Christensen ,  Nathan Hamilton ,  Stephen J. Williams

    发明人： John Roy Kane ,  Scott A. Christensen ,  Nathan Hamilton ,  Stephen J. Williams

    IPC分类号： A61H7/00 ,  A61H1/00

    CPC分类号： A61H7/001 ,  A61H2201/0103 ,  A61H2201/0207 ,  A61H2201/0214 ,  A61H2201/0228 ,  A61H2201/0242 ,  A61H2201/025 ,  A61H2201/165 ,  A61H2201/5071 ,  A61H2205/065 ,  A61H2205/12 ,  A61H2230/50

    摘要： A method and device for increasing blood flow by applying positive pressure to extremities of a mammal and/or controlling the temperature of the mammal. The device includes one or more collapsible and pliant body elements capable of expanding and flexibly applying pressurized compression forces to the extremity of the mammal by attaching one or more pressure-applying gas plenums as close to the extremity as possibly. The flexible extremity device can be used independently or can be used in conjunction with thermal pads disposed to the one or more collapsible and pliant body elements. Alternatively, the one or more collapsible and pliant body elements can be manufactured into thermal pads.

    摘要翻译： 一种通过向哺乳动物的四肢施加正压和/或控制哺乳动物的温度来增加血流量的方法和装置。 该装置包括一个或多个可折叠和柔韧的身体元件，其能够通过将一个或多个压力施加气体增压室尽可能靠近地附接到末端而扩展并且将加压的压缩力施加到哺乳动物的末端。 柔性末端装置可以独立使用，也可以与设置在一个或多个可折叠和柔韧的身体元件上的热垫结合使用。 或者，可以将一个或多个可折叠和柔韧的主体元件制造成热垫。

    Tandem isotachophoresis/zone electrophoresis method and system
    10.
    发明授权
    Tandem isotachophoresis/zone electrophoresis method and system 有权
    串联等电泳/区域电泳方法和系统

    公开(公告)号：US07494577B2

    公开(公告)日：2009-02-24

    申请号：US10676857

    申请日：2003-09-30

    申请人： Stephen J. Williams ,  Hong Dong Tan ,  Hung Pin Kao ,  Wyatt N. Vreeland

    发明人： Stephen J. Williams ,  Hong Dong Tan ,  Hung Pin Kao ,  Wyatt N. Vreeland

    IPC分类号： G01N27/447

    CPC分类号： B01L3/5027 ,  B01L3/502753 ,  B01L2200/0605 ,  B01L2300/0816 ,  B01L2400/0415 ,  B01L2400/0421 ,  B01L2400/049 ,  C07K1/26 ,  C07K1/28 ,  G01N27/44773

    摘要： A method of separating components having a given negative or positive charge and contained in a sample is disclosed. The method involves, in one embodiment, loading a microchannel with a sample, placed between a trailing-edge electrolyte having a selected concentration of a titratable species, and a leading-edge electrolyte. With the application of a voltage potential across the microchannel, charged components in the sample stack by isotachophoresis, and electrolytic hydroxyl or hydrogen ions formed by electrolysis at the upstream-end electrode migrate into the trailing-edge ion buffer, titrating the titratable species therein, where the concentration of the titratable species in the trailing-edge electrolyte is selected , in relation to the lengths of the upstream channel region and sample-loading volume, to permit the sample to stack into a relatively small sample volume before electrolytic-ion migration from the upstream electrode into and through the sample-volume region is effective to overtake the charge sample components. With continued application of an electric potential across the channel ends, charged sample components in the stacked sample volume separated by zone electrophoresis.

    摘要翻译： 公开了一种分离具有给定负电荷并包含在样品中的组分的方法。 在一个实施方案中，该方法包括将具有样品的微通道加载到放置在具有选定浓度的可滴定物质的后缘电解质和前沿电解质之间。 通过在微通道上施加电压电位，通过等速电泳施加样品叠层中的带电组分，并且通过在上游端电极处电解形成的电解羟基或氢离子迁移到后缘离子缓冲液中，滴定其中的可滴定物质， 其中选择后缘电解质中的可滴定物质的浓度，相对于上游通道区域的长度和样品加载体积，以允许样品在电离离子迁移之前堆积成相对小的样品体积 进入和通过样品体积区域的上游电极有效地超过电荷样品组分。 通过在通道末端继续施加电位，通过区域电泳分离的堆叠样品体积中的带电样品组分。