-
公开(公告)号:US20200306232A1
公开(公告)日:2020-10-01
申请号:US16308672
申请日:2017-06-08
发明人: Carlos Antonio TRINDADE DA SILVA , Buce D. HAMMOCK , Fawaz G. HAJ , Ahmed BETTAIEB , Ahmet Bora INCEOGLU
IPC分类号: A61K31/4468 , A61P19/08 , C12N15/113 , A61K9/00
摘要: Provided are compositions and methods for preventing, mitigating, decreasing, inhibiting and/or reversing bone loss and/or increasing and/or promoting bone regeneration and remodeling and/or preventing, mitigating, decreasing, inhibiting and/or reversing periodontitis and/or periodontal disease in a subject by administering to the subject an effective amount of an inhibitor of soluble epoxide hydrolase (sEH).
-
公开(公告)号:US10777724B2
公开(公告)日:2020-09-15
申请号:US16049205
申请日:2018-07-30
申请人: GAS TECHNOLOGY INSTITUTE , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ON BEHALF OF ITS MERCED CAMPUS , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ON BEHALF OF ITS BERKELEY CAMPUS
IPC分类号: H01L35/02 , H01L31/046 , H02S40/22 , H02S40/44 , F24S23/70
摘要: A hybrid solar system including a hybrid solar collector using non-imaging optics and photovoltaic components and a heat transfer and storage system in thermal communication with the hybrid solar collector, the heat transfer and storage system using particle laden gas as thermal media to simultaneously generate and store electricity and high temperature dispatchable heat.
-
公开(公告)号:US20240364139A1
公开(公告)日:2024-10-31
申请号:US18654919
申请日:2024-05-03
发明人: Hongming Lyu , Aydin Babakhani
CPC分类号: H02J50/12 , H02J50/005 , H02J50/20 , H02J50/80 , A61N1/3787 , H02J2310/23 , H04B1/71635
摘要: Wirelessly powered receiver system and sensors are described. In an embodiment, the power receiver system, includes an inductive coil that receives wireless power from an external transmitter, a capacitor bank that optimizes power transfer to an energy harvesting device, and a power-receiving frontend RF-DC rectifier with a periodically enabled closed feedback loop that adapts settings of the capacitor bank in real-time to adapt to changes on the inductive coil to maximize power transfer efficiency.
-
公开(公告)号:US20240352498A1
公开(公告)日:2024-10-24
申请号:US18751380
申请日:2024-06-24
发明人: Yuzhong Liu , Samantha Aiko Crowe , Jay D. Keasling , Xiaoyue Chen , Graham Arthur Hudson , Fei Gan , Henrik V. Scheller , James Reed , Laetitia Martin
CPC分类号: C12P19/60 , C12N9/0069 , C12N9/0083 , C12N9/1077 , C12N9/1205 , C12N9/1241 , C12N9/88 , C12P5/007 , C12Y113/99001 , C12Y114/99 , C12Y207/01043 , C12Y207/07064 , C12Y402/01076
摘要: The present invention relates inter alia to methods of biosynthetic production of QS-21, precursors and variants thereof, and to related aspects.
-
公开(公告)号:US20240350629A1
公开(公告)日:2024-10-24
申请号:US18681457
申请日:2022-08-12
发明人: Young Jik Kwon , Jee Young Chung
IPC分类号: A61K39/00 , A61K39/215 , A61P37/04
CPC分类号: A61K39/4622 , A61K39/215 , A61K39/4612 , A61K39/4614 , A61K39/4615 , A61K39/4641 , A61K39/4644 , A61K39/4648 , A61K39/464838 , A61P37/04
摘要: The disclosure provides for compositions and methods comprising cell-derived vesicles induced from cells that have been genetically engineered or infected to express specific antigen(s), and uses thereof, including as a cell-free, cell-like vaccine.
-
公开(公告)号:US20240350559A1
公开(公告)日:2024-10-24
申请号:US18541238
申请日:2023-12-15
IPC分类号: A61K35/74 , C07K14/245 , C12N1/20 , A61K35/00
CPC分类号: A61K35/74 , C07K14/245 , C12N1/20 , A61K2035/115
摘要: Provided herein are multi-strain population control systems, methods, kits, and compositions. Also provided are methods, systems, kits, and compositions for culturing bacterial cells in multi-strain ecosystems, and temporally arranged multi-strain ecosystems or cultures using a synchronized lysis circuit in combination with multiple toxin/antitoxin systems to cycle continuously over a long period of time.
-
公开(公告)号:US20240350422A1
公开(公告)日:2024-10-24
申请号:US18580090
申请日:2022-07-25
CPC分类号: A61K9/5184 , A61K9/5192 , A61K35/76
摘要: Proteinaceous nanoparticles can be used to deliver large payloads of active ingredients, which is advantageous in medicine and agriculture. However, the conjugation of hydrophobic ligands to hydrophilic nanocarriers such as plant viral nanoparticles (plant VNPs) can result in aggregation by reducing overall solubility. Provided herein are improved methods for ligand conjugations, as well as the particles prepared by these methods. The disclosed methods promote efficient bioconjugation and prevent the aggregation that accompanies conventional bioconjugation methods, thus improving the stability, homogeneity, and translational potential of plant VNP conjugates in medicine and agriculture.
-
公开(公告)号:US12121634B2
公开(公告)日:2024-10-22
申请号:US17989281
申请日:2022-11-17
IPC分类号: A61L31/10 , A01N33/00 , A01N33/12 , A01N33/20 , A01N41/06 , A61L17/00 , A61L17/14 , A61L27/34 , A61L27/54 , A61L29/08 , A61L29/16 , A61L31/16 , C08F220/38 , C08J3/24 , C08J7/04 , C08J7/056 , C09D5/00 , C09D133/14 , C09D183/04
CPC分类号: A61L31/10 , A01N33/00 , A01N33/12 , A01N33/20 , A01N41/06 , A61L17/005 , A61L17/145 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/16 , C08F220/387 , C08J3/245 , C08J7/0427 , C08J7/056 , C09D5/00 , C09D133/14 , C09D183/04 , A61L2300/404 , A61L2300/408 , A61L2420/02 , C08F2800/10 , C08F2810/20 , C08J2383/04 , C08J2433/14 , A61L17/145 , C08L33/14 , A61L27/34 , C08L33/14 , A61L29/085 , C08L33/14 , A61L31/10 , C08L33/14 , C08F220/387 , C08F220/606
摘要: Disclosed herein are compositions to use in biofouling-resistant coatings, biofouling-resistant coatings, methods of making biofouling-resistant coatings, biofouling-resistant devices, and methods of making biofouling-resistant devices.
-
公开(公告)号:US20240347502A1
公开(公告)日:2024-10-17
申请号:US18755249
申请日:2024-06-26
申请人: The Regents of the University of California , Georgia Tech Research Corporation , Wayne State University
发明人: Mike Breeden , Victor Wang , Andrew Kummel , Ming-Jui Li , Muhannad Bakir , Jonathan Hollin , Nyi Myat Khine Linn , Charles H. Winter
IPC分类号: H01L23/00
CPC分类号: H01L24/82 , H01L24/24 , H01L2224/24145 , H01L2224/24225 , H01L2224/245 , H01L2224/2511 , H01L2224/82108 , H01L2924/01027 , H01L2924/01042 , H01L2924/01044 , H01L2924/01074
摘要: Methods of bonding and structures with such bonding are disclosed. One such method includes providing a first substrate with a first electrical contact; providing a second substrate with a second electrical contact above the first electrical contact, wherein an upper surface of the first electrical contact is spaced apart from a lower surface of the second electrical contact by a gap; and depositing a layer of selective metal on the lower surface of the second electrical contact and on the upper surface of the first electrical contact by a thermal Atomic Layer Deposition (ALD) process until the gap is filled to create a bond between the first electrical contact and the second electrical contact.
-
公开(公告)号:US20240346379A1
公开(公告)日:2024-10-17
申请号:US18633905
申请日:2024-04-12
IPC分类号: G06N20/00
CPC分类号: G06N20/00
摘要: A computing system determines a median of a first number of mean values received from a first number of clusters, where each cluster of the first number of clients includes a first plurality of clients. Also, a threshold is determined based on the median, where the threshold applies to model updates. The median and the threshold are broadcast to all clients. Next, one or more clients that fail to provide a proof attesting that their model update is within the threshold of the median are dropped. Then, a second plurality of clients, not including the one or more dropped clients, participate in a final round of secure aggregation. Next, a final aggregate result is obtained, where the final aggregate result is based on the final round of secure aggregation. Then, one or more actions are performed based on the final aggregate result.
-
-
-
-
-
-
-
-
-