公开(公告)号：US09265970B2

公开(公告)日：2016-02-23

申请号：US13393418

申请日：2011-03-02

申请人： Taizo Honda ,  Masahiro Ikeda

发明人： Taizo Honda ,  Masahiro Ikeda

IPC分类号： H01J3/26 ,  A61N5/10

CPC分类号： A61N5/1043 ,  A61N5/1067 ,  A61N5/1068 ,  A61N2005/1059 ,  A61N2005/1087 ,  A61N2005/1095

摘要： A particle beam irradiation system comprises deflection electromagnets which scan by deflecting the particle beam in two dimensions in the lateral direction which is perpendicular to an irradiation direction of the particle beam, and an energy width expanding device through which the particle beam passes so as to expand an energy width of the particle beam and form a SOBP in a depth direction of the irradiation target, that is, in an irradiation direction of the particle beam, wherein the energy width expanding device is configured to form the SOBP in the depth direction along whole irradiation area in the depth direction of the irradiation target, and the deflection electromagnets are controlled so as for an irradiation spot which is formed in the irradiation target by the particle beam to move stepwise along whole irradiation area in the lateral direction of the irradiation target.

摘要翻译： 粒子束照射系统包括偏转电磁体，该偏转电磁体通过在与粒子束的照射方向垂直的横向方向上的二维偏转粒子束进行扫描;以及能量扩大装置，粒子束通过该能量扩张装置以扩展 粒子束的能量宽度，并且在照射对象的深度方向，即在粒子束的照射方向上形成SOBP，其中，能量宽度扩展装置被构造成沿着整个深度方向形成SOBP 照射对象的深度方向的照射区域，并且对于通过粒子束形成在照射对象物上的照射点，控制偏转电磁体，沿着照射对象的横向的整个照射区域逐步移动。

公开(公告)号：US08854048B2

公开(公告)日：2014-10-07

申请号：US13262866

申请日：2011-03-10

申请人： Toshihiro Otani ,  Hisashi Harada ,  Masahiro Ikeda ,  Kazushi Hanakawa ,  Taizo Honda

发明人： Toshihiro Otani ,  Hisashi Harada ,  Masahiro Ikeda ,  Kazushi Hanakawa ,  Taizo Honda

IPC分类号： G01N27/62 ,  A61N5/10

CPC分类号： H01J37/304 ,  A61N5/1048 ,  A61N5/1071 ,  A61N5/1077 ,  A61N2005/1087 ,  H01J47/02

摘要： In a particle beam therapy system which scans a particle beam and irradiates the particle beam to an irradiation position of an irradiation subject and has a dose monitoring device for measuring a dose of the particle beam and an ionization chamber smaller than the dose monitoring device, the ionization chamber measuring a dose of a particle beam passing through the dose monitoring device, the dose of the particle beam irradiated by the dose monitoring device is measured; the dose of the particle beam passing through the dose monitoring device is measured by the small ionization chamber; and a correction coefficient of the dose measured by the dose monitoring device corresponding to the irradiation position is found based on the dose of the particle beam measured by the small ionization chamber.

摘要翻译： 在粒子束治疗系统中，扫描粒子束并将粒子束照射到照射对象的照射位置，并且具有用于测量粒子束的剂量和小于剂量监测装置的电离室的剂量监测装置， 电离室测量通过剂量监测装置的粒子束的剂量，测量由剂量监测装置照射的粒子束的剂量; 通过小电离室测量通过剂量监测装置的粒子束的剂量; 并且基于由小电离室测量的粒子束的剂量，求出由与照射位置对应的剂量监测装置测量的剂量的校正​​系数。

公开(公告)号：US08658991B2

公开(公告)日：2014-02-25

申请号：US13003688

申请日：2009-06-03

申请人： Yuehu Pu ,  Katsuhisa Yoshida ,  Yuichi Yamamoto ,  Hidenobu Sakamoto ,  Taizo Honda ,  Hisashi Harada ,  Takaaki Iwata

发明人： Yuehu Pu ,  Katsuhisa Yoshida ,  Yuichi Yamamoto ,  Hidenobu Sakamoto ,  Taizo Honda ,  Hisashi Harada ,  Takaaki Iwata

IPC分类号： A61N5/00

CPC分类号： A61N5/10 ,  A61N5/1043 ,  A61N2005/1087

摘要： In order to obtain a particle beam irradiation apparatus that enlarges the dose distribution of beam spots while suppressing a decrease of the maximum available range of a charged particle beam, the particle beam irradiation apparatus includes a particle beam acceleration means; particle beam transport means; scanning apparatus that includes first scanning means and second scanning means, and two-dimensionally scans the beam; and irradiation control means that controls the scanning apparatus so as to irradiate the beam onto a target region including a plurality of small regions. The irradiation control means controls the first scanning means so as to scan the beam over a small region serving as an irradiation subject among the plurality of the small regions, and controls the second scanning means so as to change the small region serving as the irradiation subject to be a different small region among the plurality of the small regions.

摘要翻译： 为了获得粒子束照射装置，其粒子束照射装置包括粒子束加速装置，粒子束照射装置在抑制带电粒子束的最大可用范围的减小的同时，扩大束斑的剂量分布， 粒子束传送装置; 扫描装置，其包括第一扫描装置和第二扫描装置，并二维地扫描光束; 以及照射控制装置，其控制扫描装置以将束照射到包括多个小区域的目标区域上。 照射控制装置控制第一扫描装置，以便在多个小区域中的用作照射对象的小区域上扫描光束，并且控制第二扫描装置以改变用作照射对象的小区域 成为多个小区域中的不同小区域。

公开(公告)号：US20130053617A1

公开(公告)日：2013-02-28

申请号：US13696736

申请日：2011-06-22

申请人： Yuehu Pu ,  Hisashi Harada ,  Taizo Honda

发明人： Yuehu Pu ,  Hisashi Harada ,  Taizo Honda

IPC分类号： A61N5/10

CPC分类号： G21K1/046 ,  A61N5/1043 ,  A61N5/1045 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1054 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K1/10 ,  G21K5/00

摘要： A particle beam irradiation apparatus comprises a particle beam shielding member which shields a part of a particle beam which is scanned, a prompt signal detector which detects a prompt signal which is generated when the particle beam which is scanned collides with the particle beam shielding member and a signal comparison device which predicts and obtains a generation pattern of a prompt signal which is generated with a predetermined scanning pattern and stores as a signal time pattern for comparison, wherein the signal comparison device detects an abnormality of scanning of a particle beam or the particle beam shielding member by comparing a detected signal time pattern which is a time pattern of a signal which is detected by the prompt signal detector to a signal time pattern for comparison which is stored.

摘要翻译： 粒子束照射装置包括：屏蔽被扫描的粒子束的一部分的粒子束屏蔽构件;检测当被扫描的粒子束与粒子束屏蔽构件相撞时产生的提示信号的迅速信号检测器;以及 信号比较装置，其预测并获得以预定扫描图案生成的提示信号的生成模式，并存储为用于比较的信号时间图案，其中信号比较装置检测粒子束或粒子的扫描异常 通过将作为由快速信号检测器检测的信号的时间图案的检测信号时间图案与存储的用于比较的信号时间模式进行比较来检测光束屏蔽部件。

公开(公告)号：US20110108737A1

公开(公告)日：2011-05-12

申请号：US13003688

申请日：2009-06-03

申请人： Yuehu Pu ,  Katsuhisa Yoshida ,  Yuichi Yamamoto ,  Hidenobu Sakamoto ,  Taizo Honda ,  Hisashi Harada ,  Takaaki Iwata

发明人： Yuehu Pu ,  Katsuhisa Yoshida ,  Yuichi Yamamoto ,  Hidenobu Sakamoto ,  Taizo Honda ,  Hisashi Harada ,  Takaaki Iwata

IPC分类号： H01J37/147

CPC分类号： A61N5/10 ,  A61N5/1043 ,  A61N2005/1087

摘要： In order to obtain a particle beam irradiation apparatus that enlarges the dose distribution of beam spots while suppressing a decrease of the maximum available range of a charged particle beam, the particle beam irradiation apparatus includes a particle beam acceleration means; particle beam transport means; scanning apparatus that includes first scanning means and second scanning means, and two-dimensionally scans the beam; and irradiation control means that controls the scanning apparatus so as to irradiate the beam onto a target region including a plurality of small regions. The irradiation control means controls the first scanning means so as to scan the beam over a small region serving as an irradiation subject among the plurality of the small regions, and controls the second scanning means so as to change the small region serving as the irradiation subject to be a different small region among the plurality of the small regions.

摘要翻译： 为了获得粒子束照射装置，其粒子束照射装置包括粒子束加速装置，粒子束照射装置在抑制带电粒子束的最大可用范围的减小的同时，扩大束斑的剂量分布， 粒子束传送装置; 扫描装置，其包括第一扫描装置和第二扫描装置，并二维地扫描光束; 以及照射控制装置，其控制扫描装置以将束照射到包括多个小区域的目标区域上。 照射控制装置控制第一扫描装置，以便在多个小区域中的用作照射对象的小区域上扫描光束，并且控制第二扫描装置以改变用作照射对象的小区域 成为多个小区域中的不同小区域。

公开(公告)号：US09327140B2

公开(公告)日：2016-05-03

申请号：US14115028

申请日：2011-08-23

申请人： Taizo Honda ,  Yuichi Yamamoto ,  Yuehu Pu

发明人： Taizo Honda ,  Yuichi Yamamoto ,  Yuehu Pu

IPC分类号： G01K1/08 ,  A61N5/10 ,  G21K5/04

CPC分类号： A61N5/1048 ,  A61N5/1043 ,  A61N5/1075 ,  A61N5/1077 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K5/04

摘要： A beam data processing apparatus has a plurality of channel data conversion units that convert a plurality of analogue signals outputted from a position monitor into digital signals, a position size processing unit that calculates a beam position, based on voltage information items obtained through processing by the plurality of channel data conversion units, an abnormality determination processing unit that determines the beam position and generates a position abnormality signal, and an integrated control unit that controls the plurality of channel data conversion units in such a way that while a beam is stopped at an irradiation spot, digital signal conversion processing is implemented two or more times; the channel data conversion unit has a plurality of A/D converters, a demultiplexer that distributes analogue signals, and a multiplexer that switches respective digital signals processed by the A/D converters so as to output them to the position size processing unit.

摘要翻译： 波束数据处理装置具有多个通道数据转换单元，其将从位置监视器输出的多个模拟信号转换为数字信号，位置大小处理单元，基于通过处理所获得的电压信息项，计算波束位置 多个通道数据转换单元，确定光束位置并产生位置异常信号的异常判定处理单元，以及控制多个通道数据转换单元的集成控制单元，使得当光束停止在 照射点，数字信号转换处理两次以上; 信道数据转换单元具有多个A / D转换器，分配模拟信号的多路分解器和切换由A / D转换器处理的各个数字信号的多路复用器，以便将它们输出到位置大小处理单元。

公开(公告)号：US20140228615A1

公开(公告)日：2014-08-14

申请号：US14240650

申请日：2011-11-03

申请人： Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

发明人： Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

IPC分类号： A61N5/10

CPC分类号： A61N5/1081 ,  A61N5/1077 ,  A61N2005/1087 ,  A61N2005/1095

摘要： A particle beam irradiation apparatus according to the present invention is provided with a vacuum duct that forms a vacuum region through which the charged particle beam passes, a vacuum window through which the charged particle beam is launched from the vacuum region, a scanning electromagnet that scans the charged particle beam; a monitoring apparatus including a position monitor that detects the passing position of a charged particle beam and the beam size thereof, a low-scattering gas filling chamber including the monitoring apparatus, and an irradiation management apparatus that controls irradiation of the charged particle beam; the particle beam irradiation apparatus is characterized in that the low-scattering gas filling chamber is changeably disposed in such a manner that the beam-axis-direction positional relationship between the monitoring apparatus and the vacuum window is a desired one and in that the low-scattering gas filling chamber is filled with a low-scattering gas.

摘要翻译： 根据本发明的粒子束照射装置设置有真空管道，该真空管道形成带电粒子束通过的真空区域，从真空区域发射带电粒子束的真空窗口，扫描的扫描电磁体 带电粒子束; 监视装置，其包括检测带电粒子束的通过位置的位置监视器及其光束尺寸，包括监视装置的低散射气体填充室以及控制带电粒子束的照射的照射管理装置; 所述粒子束照射装置的特征在于，所述低散射气体充填室可变地设置成使得所述监视装置和所述真空窗口之间的射束轴向位置关系是期望的， 散射气体填充室填充有低散射气体。

公开(公告)号：US20140187847A1

公开(公告)日：2014-07-03

申请号：US14240197

申请日：2011-11-02

申请人： Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

发明人： Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

IPC分类号： A61N5/10

CPC分类号： A61N5/1077 ,  A61N5/1049 ,  A61N5/1069 ,  A61N2005/1087

摘要： A particle beam therapy system comprising a treatment table, a treatment table control unit and an irradiation control unit configured to output an instruction for controlling the treatment table control unit, an accelerator and a scanning electromagnet, wherein after the treatment table control unit controls the treatment table so as for a patient isocenter which is reference position of an affected area of a patient to move to a position of an irradiation isocenter which is set at a position which is closer to an irradiation nozzle than an equipment isocenter which is reference of positional relation of the irradiation nozzle and the treatment table, the irradiation control unit outputs an instruction for irradiating the patient with a particle beam.

摘要翻译： 一种粒子束治疗系统，包括治疗台，治疗台控制单元和照射控制单元，其被配置为输出用于控制治疗台控制单元的指令，加速器和扫描电磁体，其中在治疗台控制单元控制治疗 将患者的中心位置作为患者的受影响区域的基准位置移动到被设定在比作为位置关系的参照的设备等角点更靠近照射喷嘴的位置的照射等角点的位置 的照射喷嘴和处理台，照射控制单元输出用于对粒子束照射患者的指示。

公开(公告)号：US20140061498A1

公开(公告)日：2014-03-06

申请号：US14115028

申请日：2011-08-23

申请人： Taizo Honda ,  Yuichi Yamamoto ,  Yuehu Pu

发明人： Taizo Honda ,  Yuichi Yamamoto ,  Yuehu Pu

IPC分类号： A61N5/10

CPC分类号： A61N5/1048 ,  A61N5/1043 ,  A61N5/1075 ,  A61N5/1077 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K5/04

摘要： A beam data processing apparatus has a plurality of channel data conversion units that convert a plurality of analogue signals outputted from a position monitor into digital signals, a position size processing unit that calculates a beam position, based on voltage information items obtained through processing by the plurality of channel data conversion units, an abnormality determination processing unit that determines the beam position and generates a position abnormality signal, and an integrated control unit that controls the plurality of channel data conversion units in such a way that while a beam is stopped at an irradiation spot, digital signal conversion processing is implemented two or more times; the channel data conversion unit has a plurality of A/D converters, a demultiplexer that distributes analogue signals, and a multiplexer that switches respective digital signals processed by the ND converters so as to output them to the position size processing unit.

摘要翻译： 波束数据处理装置具有多个通道数据转换单元，其将从位置监视器输出的多个模拟信号转换为数字信号，位置大小处理单元，基于通过处理所获得的电压信息项，计算波束位置 多个通道数据转换单元，确定光束位置并产生位置异常信号的异常判定处理单元，以及控制多个通道数据转换单元的集成控制单元，使得当光束停止在 照射点，数字信号转换处理两次以上; 信道数据转换单元具有多个A / D转换器，分配模拟信号的多路分解器，以及多路复用器，其切换由ND转换器处理的各个数字信号，以将其输出到位置大小处理单元。

公开(公告)号：US20130320245A1

公开(公告)日：2013-12-05

申请号：US13985759

申请日：2011-04-25

申请人： Yuehu Pu ,  Taizo Honda ,  Takaaki Iwata

发明人： Yuehu Pu ,  Taizo Honda ,  Takaaki Iwata

IPC分类号： A61N5/10

CPC分类号： A61N5/1048 ,  A61N5/1042 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K1/10

摘要： There is provided a particle-beam energy changing apparatus that is capable of changing energy of a particle beam quickly and silently, in which a first energy changing unit and a second energy changing unit for changing energy of a particle beam passing therethrough by varying thicknesses of their attenuators attenuating the particle beam energy are arranged so that the particle beam passes through the first energy changing unit and the second energy changing unit; and the maximum attenuation amount by the first energy changing unit is set smaller than the maximum attenuation amount by the second energy changing unit.

摘要翻译： 提供了一种能够快速且静默地改变粒子束能量的粒子束能量改变装置，其中第一能量改变单元和第二能量改变单元用于通过改变粒子束的厚度来改变通过其的粒子束的能量 其衰减粒子束能量的衰减器被布置成使得粒子束通过第一能量改变单元和第二能量改变单元; 并且第一能量改变单元的最大衰减量被设定为小于第二能量变化单元的最大衰减量。