Vascular Aging-Predicting Factor and Utilization of the Same
    2.
    发明申请
    Vascular Aging-Predicting Factor and Utilization of the Same 审中-公开
    血管老化预测因子及其应用

    公开(公告)号:US20090136985A1

    公开(公告)日:2009-05-28

    申请号:US12085656

    申请日:2006-10-30

    CPC classification number: G01N33/6893 C07K14/775 C07K16/18 G01N2800/32

    Abstract: Abstract A predicting factor for vascular aging and an examination method for an early-stage lesion resulting from vascular aging are provided. Specifically, a predicting factor for vascular aging comprising a human apolipoprotein B100 having a glutathionylated thiol group; a method of examining a lesion resulting from vascular aging contain measurement of a human apolipoprotein B100 having a glutathionylated thiol group in the blood sample; an antibody specifically recognizing an apolipoprotein B100 having a glutathionylated thiol group; a diagnostic agent or a diagnostic kit for an early-stage lesion resulting from vascular aging containing an antibody recognizing a human apolipoprotein B100 having a glutathionylated thiol group, are provided.

    Abstract translation: 摘要提供血管老化预后因素及血管老化引起的早期病变检查方法。 具体地说,包含具有谷胱甘肽化硫醇基的人载脂蛋白B100的血管老化的预测因子; 检查由血管衰老引起的病变的方法包括测定血液样品中具有谷胱甘肽化硫醇基的人载脂蛋白B100; 特异性识别具有谷胱甘肽化硫醇基的载脂蛋白B100的抗体; 提供了由含有识别具有谷胱甘肽化硫醇基团的人载脂蛋白B100的抗体的血管老化引起的早期病变的诊断试剂或诊断试剂盒。

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