公开(公告)号：US4801720A

公开(公告)日：1989-01-31

申请号：US46444

申请日：1987-05-06

申请人： Sigeru Torii ,  Hideo Tanaka ,  Junzo Nokami ,  Michio Sasaoka ,  Norio Saito ,  Takashi Siroi

发明人： Sigeru Torii ,  Hideo Tanaka ,  Junzo Nokami ,  Michio Sasaoka ,  Norio Saito ,  Takashi Siroi

IPC分类号： C07D205/08 ,  C07D205/095 ,  C07D403/12 ,  C07D417/12 ,  C07D417/14 ,  C07D501/20 ,  C07D501/36 ,  C07B43/06 ,  C07B45/00 ,  C07D401/12

CPC分类号： C07D403/12 ,  C07D205/095 ,  C07D417/12 ,  C07D417/14 ,  Y02P20/55

摘要： An azetidinone derivative represented by the formula (I) ##STR1## wherein R.sup.1 is substituted or unsubstituted phenyl or substituted or unsubstituted phenoxy, R.sup.2 is hydrogen, optionally substituted hydrocarbon residue or amino-protecting group selected from acyl, silyl, sulfonyl and phosphonyl derived from organic or inorganic acid, ##STR2## is >C.dbd.O or>C.dbd.N--OR.sup.3 (wherein R.sup.3 is hydrogen or lower alkyl), X.sup.1 and X.sup.2 are the same or different and are halogen, hydroxyl, alkoxy, acyloxy, SR.sup.4 (wherein R.sup.4 is straight chain or branched chain lower alkyl substituted or unsubstituted, substituted or unsubstituted phenyl or substituted or unsubstituted heterocyclic group), amino or hydrogen, one of X.sup.1 and X.sup.2 being hydrogen when the other is not, and R.sup.5 is substituted or unsubstituted phenyl or substituted or unsubstituted heterocyclic group, and a process for preparing the same.

摘要翻译： 由式（I）表示的氮杂环丁酮衍生物其中R1是取代或未取代的苯基或取代或未取代的苯氧基，R2是氢，任选取代的烃残基或氨基保护基，其选自酰基，甲硅烷基，磺酰基和 衍生自有机或无机酸的膦酰基是C = O或C = N-OR 3（其中R 3为氢或低级烷基），X 1和X 2相同或不同，为卤素，羟基，烷氧基，酰氧基 ，SR4（其中R4是直链或支链低级烷基取代或未取代的，取代或未取代的苯基或取代或未取代的杂环基），氨基或氢，当另一个未被取代时，X 1和X 2之一为氢，R 5为取代基 或未取代的苯基或取代或未取代的杂环基，及其制备方法。

公开(公告)号：US4810788A

公开(公告)日：1989-03-07

申请号：US46423

申请日：1987-05-06

申请人： Sigeru Torii ,  Hideo Tanaka ,  Junzo Nokami ,  Michio Sasaoka ,  Norio Saito ,  Takashi Siroi

发明人： Sigeru Torii ,  Hideo Tanaka ,  Junzo Nokami ,  Michio Sasaoka ,  Norio Saito ,  Takashi Siroi

IPC分类号： C07D205/08 ,  C07D205/095 ,  C07D403/12 ,  C07D417/12 ,  C07D417/14 ,  C07D501/20 ,  C07D501/36 ,  C07D401/12 ,  C07D401/14

CPC分类号： C07D403/12 ,  C07D205/095 ,  C07D417/12 ,  C07D417/14 ,  Y02P20/55

摘要： An azetidinone derivative represented by the formula (I) ##STR1## wherein R.sup.1 is substituted or unsubstituted phenyl or substituted or unsubstituted phenoxy, R.sup.2 is hydrogen, optionally substituted hydrocarbon residue or aminoprotecting group selected from acyl, silyl, sulfonyl and phosphonyl derived from organic or inorganic acid, ##STR2## (wherein R.sup.3 is hydrogen or lower alkyl), X.sup.1 and X.sup.2 are the same or different and are halogen, hydroxyl, alkoxy, acyloxy, SR.sup.4 (wherein R.sup.4 is straight chain or branched chain lower alkyl substituted or unsubstituted, substituted or unsubstituted phenyl or substituted or unsubstituted heterocyclic group), amino or hydrogen, one of X.sup.1 and X.sup.2 being hydrogen when the other is not, and R.sup.5 is substituted or unsubstituted phenyl or substituted or unsubstituted heterocyclic group, and a process for preparing the same.

摘要翻译： 由式（I）表示的氮杂环丁酮衍生物其中R1是取代或未取代的苯基或取代或未取代的苯氧基，R2是氢，任选取代的烃残基或选自酰基，甲硅烷基，磺酰基和膦酰基的氨基保护基 由有机或无机酸形成，其中R 3为氢或低级烷基，X 1和X 2相同或不同，为卤素，羟基，烷氧基，酰氧基，SR4（其中R4为直链或支链低级烷基取代的 或未取代的，取代或未取代的苯基或取代或未取代的杂环基），氨基或氢，当另一个未被取代时，X 1和X 2为氢，R 5为取代或未取代的苯基或取代或未取代的杂环基， 准备一样