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    System for genome analysis and genetic disease diagnosis
    4.
    发明授权
    System for genome analysis and genetic disease diagnosis 有权

    公开(公告)号：US09940434B2

    公开(公告)日：2018-04-10

    申请号：US14431702

    申请日：2013-09-27

    申请人： THE CHILDREN'S MERCY HOSPITAL

    发明人： Stephen Kingsmore ,  Neil Miller ,  Carol Saunders ,  Sarah Soden ,  Emily G. Farrow

    IPC分类号： C40B60/10 ,  G06F19/18

    CPC分类号： G06F19/18

    摘要： The method for genome analysis translates the clinical findings in the patient into a comprehensive test order for genes that can be causative of the patient's illness, delimits analysis of variants identified in the patient's genome to those that are “on target” for the patient's illness, and provides clinical annotation of the likely causative variants for inclusion in a variant warehouse that is updated as a result of each sample that is analyzed and that, in turn, provides a source of additional annotation for variants. The method uses a genome sequence having the steps of entering at least one clinical feature of a patient by an end-user, assigning a weighted value to the term based on the probability of the presence of the term, mapping the term to at least one disease by accessing a knowledge base containing a plurality of data sets, wherein the data sets are made up of associations between (i) clinical features and diseases, (ii) diseases and genes, (iii) genes and genetic variants, and (iv) diseases and gene variants, assigning a truth value to each of the mapped terms based on the associated data sets and the weighted value, to provide a list of results of possible diagnoses prioritized based on the truth values, with continuous adjustment of the weightings of associations in the knowledge base based on updating of each discovered diagnosis and attendant clinical features, genes and gene variants. This method can be performed in fifty hours or twenty-four hours or less.

    MUAC z-score tape and methods of use thereof
    7.
    发明授权
    MUAC z-score tape and methods of use thereof 有权

    公开(公告)号：US10238317B2

    公开(公告)日：2019-03-26

    申请号：US15149829

    申请日：2016-05-09

    申请人： The Children's Mercy Hospital

    发明人： Susan M. Abdel-Rahman

    IPC分类号： A41H1/02 ,  A61B5/00 ,  G01B3/10 ,  G01B5/02 ,  A61B5/107

    摘要： The present disclosure is directed towards a device, method of using a device, and a method of making a device for predicting the nutritional status in an individual of any age or weight. The device includes one or more strips for measuring the circumference of a body part of an individual. The method includes taking the girth measurement and reading a standard score from the device to estimate the nutritional status of the individual.

    MUAC Z-SCORE TAPE AND METHODS OF USE THEREOF
    9.
    发明申请
    MUAC Z-SCORE TAPE AND METHODS OF USE THEREOF 审中-公开
    MUAC Z-SCORE TAPE及其使用方法

    公开(公告)号：US20160324444A1

    公开(公告)日：2016-11-10

    申请号：US15149829

    申请日：2016-05-09

    申请人： The Children's Mercy Hospital

    发明人： Susan M. Abdel-Rahman

    IPC分类号： A61B5/107 ,  A61B5/00 ,  A61B5/103

    CPC分类号： A61B5/1075 ,  A61B5/4866 ,  A61B5/6823 ,  A61B5/6824 ,  A61B2503/04 ,  A61B2503/06

    摘要： The present disclosure is directed towards a device, method of using a device, and a method of making a device for predicting the nutritional status in an individual of any age or weight. The device includes one or more strips for measuring the circumference of a body part of an individual. The method includes taking the girth measurement and reading a standard score from the device to estimate the nutritional status of the individual.

    摘要翻译： 本公开涉及装置，使用装置的方法，以及制造用于预测任何年龄或体重的个体的营养状况的装置的方法。 该装置包括用于测量个体的身体部分的圆周的一个或多个条带。 该方法包括进行周长测量并从设备读取标准分数以估计个体的营养状况。