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1.发明公开公开(公告)号：US20240349733A1
公开(公告)日：2024-10-24
申请号：US18644446
申请日：2024-04-24
发明人： KRANTHI MANDADI , JAMES BORNEMAN , SANDUN FERNANDO , SONIA IRIGOYEN , CARMEN S. PADILLA , MANIKANDAN RAMASAMY , SAMAVATH MALLAWARACHCHI
IPC分类号： A01N63/50
CPC分类号： A01N63/50
摘要： The subject invention pertains to controlling and/or treating infections of Candidatus Liberibacter spp. that leads to citrus greening in citrus plants, such as orange trees, grapefruit trees, lime trees, lemon trees and the like and potato zebra chip disease in potato and other tuber plants using specifically targeted antimicrobial peptides (STAMPs).
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公开(公告)号：US12116533B2
公开(公告)日：2024-10-15
申请号：US17048640
申请日：2019-04-19
CPC分类号： C10G15/08 , B01J19/088 , B01J2219/00049 , B01J2219/0809 , B01J2219/0815
摘要： Disclosed are example efficient circuits that produce spark discharges for hydrocarbon conversion (or treatment of other mixtures) using a high-voltage rectified DC supply to discharge a capacitor (either internal or external) across a two-electrode gap, optimized to minimize waste energy by operating in a constant current, approximately-constant current, or constant power mode. The circuits may operate off of a standard electrical supply line (e.g. 120 VAC or 240 V AC, 60 Hz, single-phase or multi-phase). The disclosed approach is scalable to any number of discharge gaps while maintaining similar pulse characteristics and electrical efficiency.
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公开(公告)号：US20240307519A1
公开(公告)日：2024-09-19
申请号：US18576813
申请日：2022-07-07
发明人： Jamie Suzanne Benn , Chase M. Nunez , Walter E. Cook , Allison Ficht , Thomas A. Ficht , Sankar P. Chaki
CPC分类号： A61K39/07 , C12N11/10 , A61K2039/542 , A61K2039/552 , A61K2039/55555 , A61K2039/575 , C12R2001/07
摘要： Methods and compositions for the immunization of animals and humans using an immunization or vaccine that comprises B. anthracis Sterne strain 34F2 spores suspended in alginate in an amount sufficient to protect an animal or human from a lethal dose of anthrax.
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公开(公告)号：US12078388B2
公开(公告)日：2024-09-03
申请号：US17029881
申请日：2020-09-23
发明人： Shuza Binzaid
摘要： A system for enhancing overall energy production of CSPs through amplification of solar heat collection. In one embodiment, the system comprises a linear solar-thermal concentrator for concentrating solar light comprising a curved surface, two side walls, and an opening; a fluid conduit disposed within the linear solar-thermal concentrator that carries a working fluid through the linear solar-thermal concentrator; and a convection cover disposed over the opening of the linear thermal concentrator that traps heat convection energy within the linear solar-thermal concentrator.
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公开(公告)号：US12076464B2
公开(公告)日：2024-09-03
申请号：US17072166
申请日：2020-10-16
IPC分类号： A61L27/56 , A61L27/18 , A61L27/54 , C08G18/32 , C08G18/34 , C08G18/38 , C08G18/73 , C08G101/00
CPC分类号： A61L27/56 , A61L27/18 , A61L27/54 , C08G18/3206 , C08G18/341 , C08G18/3825 , C08G18/73 , A61L2300/626 , A61L2300/802 , A61L2400/16 , C08G2101/00 , C08G2280/00
摘要： Tumor resection is commonly practiced to prevent the progression of cancer. However, there are post-surgery concerns including the formation of a void that can allow cancer cells to escape at the surgery site, which increases the risk of metastasis. To counter this challenge, an embodiment includes a polyurethane-based shape memory foam as a tissue void-filling device that can also release anti-cancer drugs. Such foams may activate at body temperature and become malleable. Such properties may enable the foam to be shaped to precisely seal the tissue void and then serve as a drug-eluting device. Based on the drug composition with poly vinyl alcohol (PVA), the drug release profile from the foam may be altered depending on the application.
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公开(公告)号：US20240279603A1
公开(公告)日：2024-08-22
申请号：US18571505
申请日：2022-06-17
发明人： Arthur SEFIANI , Cedric G. GEOFFROY
IPC分类号： C12N5/0793
CPC分类号： C12N5/0619 , C12N2500/90 , C12N2501/727 , C12N2501/734 , C12N2509/10
摘要： The present disclosure provides method of processing neural cells comprising extracting one or more brain components from an animal, dissociating cells from the brain components to form a brain cell composition, purifying the neural cells from the brain cell composition, and culturing the neural cells. Further, the present disclosure provides in vitro assays and related kits utilizing the neural cells, for example in use to screen compounds or therapeutics for neurological diseases or disorders.
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公开(公告)号：US12066415B2
公开(公告)日：2024-08-20
申请号：US17554138
申请日：2021-12-17
发明人： Jun Kameoka , Onder Dincel , Ting-Yen Chi
CPC分类号： G01N31/223 , G08C17/02 , G01N33/0047 , G01N33/0054 , G01N33/02
摘要： A system for providing an indication of the presence of molecular structures in a medium is provided. The system includes a radio frequency (RF) wireless antenna, batteryless sensor, and a network analyzer. The sensor has an ultra-high frequency dipole antenna that transmits data to the RF wireless antenna and a sensing element. The sensing element is operatively coupled to the dipolar antenna and detects the presence of molecular structures. When molecular structures are detected, data indicative of the presence of the molecular structures is transmitted to a radio frequency (RF) wireless communication antenna from the dipole antenna. The network analyzer receives the data from the RF wireless antenna and analyzes the data to determine a concentration of molecular structures.
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公开(公告)号：US20240269163A1
公开(公告)日：2024-08-15
申请号：US18567972
申请日：2022-06-08
发明人： Thomas A. KENT , Paul J. DERRY , Kenneth R. OLSON
IPC分类号： A61K31/765 , A61K9/00 , A61K31/385 , A61K47/69 , A61P43/00
CPC分类号： A61K31/765 , A61K9/0053 , A61K31/385 , A61K47/6921 , A61P43/00
摘要： A method of treating a Down syndrome (DS) subject with functional or at risk of decline of organ systems associated with accelerated aging due to over-production of H2S is disclosed. That method contemplates administering a pharmaceutical composition containing a H2S-reducing effective amount of hydrophilic polymer-substituted oxidized carbon nanoparticles (OCNPs) and an optional potentiating amount of lipoic acid or dihydrolipoic acid dissolved or dispersed in a physiologically acceptable diluent to the subject. The pharmaceutical composition can be administered parenterally as a liquid or per os as a solid or liquid.
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公开(公告)号：US20240267794A1
公开(公告)日：2024-08-08
申请号：US18437149
申请日：2024-02-08
发明人： Srinivas G. Shakkottai , Woo-Hyun Ko , Harish Kumar Dureppagari , Ujwal Dinesha , Venkata Siva Santosh Ganji , Dinesh Bharadia , Raini Y. Wu , Ushasi Ghosh
摘要： In some examples, a system includes a communication network having a cloud portion and an edge portion. The communication network comprises a cloud controller, a radio access network (RAN), and an edge computing device. The edge computing device is co-located with at least a portion of the RAN. The edge computing device is configured to, within one transmission time interval (TTI) of the RAN, obtain network state information of the communication network, determine control actions for modifying operational settings of the RAN, and transmit the control actions to the RAN.
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公开(公告)号：US20240261218A1
公开(公告)日：2024-08-08
申请号：US18562374
申请日：2022-05-13
发明人： Robert Y. TSAI , Xiaohua LIU
IPC分类号： A61K9/00 , A61K9/70 , A61K31/282 , A61K31/365 , A61K31/5377 , A61K47/32 , A61K47/38 , A61K47/42
CPC分类号： A61K9/006 , A61K9/7007 , A61K31/282 , A61K31/365 , A61K31/5377 , A61K47/32 , A61K47/38 , A61K47/42
摘要： The present disclosure provides pharmaceutical formulations comprising i) a support frame, ii) one or more bioadhesive materials, iii) a first active ingredient, and iv) a second active ingredient. The disclosure also provides methods of treating a subject using the pharmaceutical formulations for various disease states and processes for making the pharmaceutical formulation.
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