公开(公告)号：US20100319836A1

公开(公告)日：2010-12-23

申请号：US12064233

申请日：2006-08-21

申请人： Thiemo Blank ,  Thomas Wille

发明人： Thiemo Blank ,  Thomas Wille

IPC分类号： B29D23/00 ,  A61F2/82

CPC分类号： A61F2/89 ,  A61F2002/072 ,  A61F2002/825 ,  A61F2002/828 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0018

摘要： A polymer prosthesis with lumen and an axial length and having in a pre-delivery condition a plurality of relatively stiff stenting segments spaced from each other along the length of the prosthesis, the spaces between the relatively stiff stenting segments of a first polymer being bridged by relatively flexible linking segments of a second polymer, different from the first, the relatively stiff stenting segments and the relatively flexible linking segments being alternately arranged along the length of the prosthesis.

摘要翻译： 一种具有内腔和轴向长度的聚合物假体，并且在预交付状态下具有沿假体长度彼此间隔开的多个相对较硬的支架构件段，第一聚合物的较硬的支架段之间的空间由 不同于第一聚合物的相对柔性的连接段，相对较硬的支架段和相对柔性的连接段沿假体的长度交替排列。

公开(公告)号：US20100242620A1

公开(公告)日：2010-09-30

申请号：US12438282

申请日：2007-08-14

申请人： Markus Lorenz ,  Thiemo Blank ,  Roman Forreiter

发明人： Markus Lorenz ,  Thiemo Blank ,  Roman Forreiter

IPC分类号： G01N3/04

CPC分类号： G01N3/04 ,  A61F2/76 ,  A61F2/82 ,  G01N2203/0208 ,  G01N2203/0274 ,  G01N2203/0405 ,  G01N2203/0452 ,  G01N2203/0458

摘要： A fatigue test system for repetitively deforming a substantially tubular implant structure which is within a radial range and within an axial range expandable and contractable and which has at least a first and a second end, wherein the system comprises at least a first and second part which are controllably moveable relative to each other, and a first and a second fixture assembly for fixing the first end to the first part and the second end to the second part, so that the system controls in use the position of each of the first and second end of the tubular implant structure.

摘要翻译： 一种疲劳测试系统，用于对基本上管状的植入结构进行重复变形，所述植入结构在径向范围内并且在可扩张和收缩的轴向范围内并具有至少第一和第二端，其中所述系统至少包括第一和第二部分， 相对于彼此可控地可移动;以及第一和第二固定装置，用于将第一端固定到第一部分，将第二端固定到第二部分，使得系统在使用中控制第一和第二部分中的每一个的位置 管状植入结构的端部。

公开(公告)号：US08672995B2

公开(公告)日：2014-03-18

申请号：US12064233

申请日：2006-08-21

申请人： Thiemo Blank ,  Thomas Wille

发明人： Thiemo Blank ,  Thomas Wille

IPC分类号： A61F2/82

CPC分类号： A61F2/89 ,  A61F2002/072 ,  A61F2002/825 ,  A61F2002/828 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0018

摘要： A polymer prosthesis with lumen and an axial length and having in a pre-delivery condition a plurality of relatively stiff stenting segments spaced from each other along the length of the prosthesis, the spaces between the relatively stiff stenting segments of a first polymer being bridged by relatively flexible linking segments of a second polymer, different from the first, the relatively stiff stenting segments and the relatively flexible linking segments being alternately arranged along the length of the prosthesis.

摘要翻译： 一种具有内腔和轴向长度的聚合物假体，并且在预交付状态下具有沿假体长度彼此间隔开的多个相对较硬的支架构件段，第一聚合物的较硬的支架段之间的空间由 不同于第一聚合物的相对柔性的连接段，相对较硬的支架段和相对柔性的连接段沿假体的长度交替排列。

公开(公告)号：US20100000329A1

公开(公告)日：2010-01-07

申请号：US12438231

申请日：2007-08-14

申请人： Markus Lorenz ,  Thiemo Blank ,  Roman Forreiter

发明人： Markus Lorenz ,  Thiemo Blank ,  Roman Forreiter

IPC分类号： G01N3/04

CPC分类号： G01N3/04 ,  A61F2/82 ,  A61F2240/008 ,  A61F2250/0018 ,  A61F2250/0062 ,  G01N2203/0274 ,  G01N2203/0405 ,  G01N2203/0441 ,  G01N2203/0452

摘要： A substantially flexible implant holder for holding a substantially tubular implant structure during fatigue testing of the implant structure, the implant holder having a substantially elongate cavity for occupation by the tubular implant structure and a cavity-surrounding part which extends from at least a first longitudinal end of the cavity to at least a second longitudinal end of the cavity, the cavity-surrounding part having a stiffness which gradually changes from a relatively high stiffness adjacent each of the longitudinal ends of the cavity to a relatively low stiffness adjacent a middle portion which is situated between the two longitudinal ends of the cavity.

摘要翻译： 一种基本上柔性的植入物保持器，用于在所述植入物结构的疲劳测试期间保持基本上管状的植入物结构，所述植入物保持器具有用于由所述管状植入结构占据的基本上细长的空腔和从至少第一纵向端延伸的空腔周围部分 所述空腔周围部分具有刚性，所述刚度从邻近所述空腔的每个所述纵向端部的相对高的刚度逐渐变化到邻近中间部分的相对低的刚度，所述中间部分是 位于空腔的两个纵向端之间。

公开(公告)号：US08347730B2

公开(公告)日：2013-01-08

申请号：US12438231

申请日：2007-08-14

申请人： Markus Lorenz ,  Thiemo Blank ,  Roman Forreiter

发明人： Markus Lorenz ,  Thiemo Blank ,  Roman Forreiter

IPC分类号： G01N3/02

CPC分类号： G01N3/04 ,  A61F2/82 ,  A61F2240/008 ,  A61F2250/0018 ,  A61F2250/0062 ,  G01N2203/0274 ,  G01N2203/0405 ,  G01N2203/0441 ,  G01N2203/0452

摘要： A substantially flexible implant holder for holding a substantially tubular implant structure during fatigue testing of the implant structure, the implant holder having a substantially elongate cavity for occupation by the tubular implant structure and a cavity-surrounding part which extends from at least a first longitudinal end of the cavity to at least a second longitudinal end of the cavity, the cavity-surrounding part having a stiffness which gradually changes from a relatively high stiffness adjacent each of the longitudinal ends of the cavity to a relatively low stiffness adjacent a middle portion which is situated between the two longitudinal ends of the cavity.

摘要翻译： 一种基本上柔性的植入物保持器，用于在所述植入物结构的疲劳测试期间保持基本上管状的植入物结构，所述植入物保持器具有用于由所述管状植入结构占据的基本上细长的空腔和从至少第一纵向端延伸的空腔周围部分 所述空腔周围部分具有刚性，所述刚度从邻近所述空腔的每个所述纵向端部的相对高的刚度逐渐变化到邻近中间部分的相对低的刚度，所述中间部分是 位于空腔的两个纵向端之间。

公开(公告)号：US20080312727A1

公开(公告)日：2008-12-18

申请号：US11572681

申请日：2005-08-01

申请人： Thiemo Blank

发明人： Thiemo Blank

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61F2230/0006 ,  A61F2230/0069 ,  A61F2240/001 ,  B23K15/08 ,  B23K26/38 ,  B23K2101/06 ,  B26F3/004

摘要： A medical implant such as a self-expanding shape memory alloy stent with a strut matrix formed by cut patterns in a wall of a tubular workpiece (12) can be enhanced by arranging for the line of the laser beam when cutting the struts (62) to be one that does not pass through the longitudinal rotational axis (10) of the tubular workpiece. Such “off-axis-” cutting can modify the cross-sectional shape and area of each strut, along its length. Such modulation can enhance the fatigue resistance of the stent matrix, or increase the radial force that the stent matrix is capable of exerting on bodily tissue within which it is implanted.

摘要翻译： 通过在切割支柱（62）时布置激光束的线，可以增强诸如具有由管状工件（12）的壁中的切割图案形成的支柱矩阵的自扩张形状记忆合金支架的医疗植入物， 不是通过管状工件的纵向旋转轴线（10）。 这种“离轴”切割可以沿其长度改变每个支柱的横截面形状和面积。 这种调节可以增强支架基质的抗疲劳性，或增加支架基质能够在植入其内的身体组织上施加的径向力。

公开(公告)号：US20060211984A1

公开(公告)日：2006-09-21

申请号：US10572333

申请日：2004-09-23

申请人： Thiemo Blank ,  Chandrashekhar Pathak

发明人： Thiemo Blank ,  Chandrashekhar Pathak

IPC分类号： A61M29/00

CPC分类号： B29C61/00 ,  A61F2/82 ,  A61F2210/0038 ,  A61F2210/0042 ,  A61F2210/0047 ,  B29C61/02 ,  B29L2031/7534

摘要： An implant having capability to expand and contract radially through a range of diameters, with corresponding changes in the cross-sectional area of the lumen, said implant exhibiting a remembered configuration in which the diameter of the implant is at the low end of said range of diameters, such that the implant is prompted to change its configuration towards said remembered configuration, that is, towards a reduced diameter configuration, upon the imposition on the implant of outside stimulus; said implant being characterised by: a molecule distributed within its bulk volume that preferentially responds to an applied field that permeates said volume, wherein said applied field constitutes the outside stimulus, and the preferential response of the molecule provides the prompt on the implant to change to the said remembered configuration.

摘要翻译： 植入物具有通过一定范围的直径而径向膨胀和收缩的能力，并且具有腔的横截面面积的相应变化，所述植入物呈现记忆结构，其中植入物的直径处于所述范围的低端 直径，使得植入物被迫改变其构型朝着所述记忆构型改变，即，在施加在外部刺激的植入物上时朝向减小的直径构型; 所述植入物的特征在于：分布在其本体体积内的分子优先响应渗透所述体积的施加的场，其中所述施加的场构成外部刺激，并且分子的优先响应提供植入物上的提示，以改变为 所记住的配置。

公开(公告)号：US08196478B2

公开(公告)日：2012-06-12

申请号：US12438282

申请日：2007-08-14

申请人： Markus Lorenz ,  Thiemo Blank ,  Roman Forreiter

发明人： Markus Lorenz ,  Thiemo Blank ,  Roman Forreiter

IPC分类号： G01N3/02 ,  G01N3/08

CPC分类号： G01N3/04 ,  A61F2/76 ,  A61F2/82 ,  G01N2203/0208 ,  G01N2203/0274 ,  G01N2203/0405 ,  G01N2203/0452 ,  G01N2203/0458

摘要： A fatigue test system for repetitively deforming a substantially tubular implant structure which is within a radial range and within an axial range expandable and contractable and which has at least a first and a second end, wherein the system comprises at least a first and second part which are controllably moveable relative to each other, and a first and a second fixture assembly for fixing the first end to the first part and the second end to the second part, so that the system controls in use the position of each of the first and second end of the tubular implant structure.

摘要翻译： 一种疲劳测试系统，用于对基本上管状的植入结构进行重复变形，所述植入结构在径向范围内并且在可扩张和收缩的轴向范围内并具有至少第一和第二端，其中所述系统至少包括第一和第二部分， 相对于彼此可控地可移动;以及第一和第二固定装置，用于将第一端固定到第一部分，将第二端固定到第二部分，使得系统在使用中控制第一和第二部分中的每一个的位置 管状植入结构的端部。

公开(公告)号：US20060173529A1

公开(公告)日：2006-08-03

申请号：US10507347

申请日：2003-03-14

申请人： Thiemo Blank

发明人： Thiemo Blank

IPC分类号： A61F2/06

CPC分类号： A61F2/915 ,  A61F2/89 ,  A61F2/91 ,  A61F2002/828 ,  A61F2002/91525 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/91591 ,  A61F2230/0054 ,  A61F2250/0039

摘要： The present invention relates to tubular radially expansible metal structures, having an abluminal wall, a luminal wall and a radial wall thickness therebetween with struts defining through-apertures in the wall, the structure further defining a plurality of expansible rings arranged adjacent one another along the longitudinal axis of the structure, each of the rings defining at least one bridge strut, and adjacent rings being linked by a bridge extending between adjacent bridge struts on adjacent rings. The bridges, a plurality of which are distributed throughout the length of the tubular structure and are configured and arranged to divide the tubular structure into axially spaced and electrically insulated sections, advantageously exhibit reduced electrical conductivity throughout their wall thickness. The present invention relates furthermore to a method of manufacturing such a tubular structure, as well as a method of visualizing a bodily lumen supported by such a tubular structure deployed therein.

摘要翻译： 本发明涉及管状径向可膨胀的金属结构，其具有中空壁，管腔壁和其间的径向壁厚，其中支撑件限定了壁中的通孔，该结构还限定沿着该壁的相邻的彼此相邻布置的多个可膨胀环 所述结构的纵向轴线中的每一个环限定至少一个桥接支柱，并且相邻的环通过在相邻环上的相邻桥接支柱之间延伸的桥连接。 桥梁，其多个分布在管状结构的整个长度上，并且被构造和布置成将管状结构分成轴向间隔的和电绝缘的部分，有利地在整个壁厚度上表现出降低的导电性。 本发明还涉及一种制造这种管状结构的方法，以及一种使由其中部署的这种管状结构支撑的身体可视化的方法。