Process for the gelatin coating of medicaments
    1.
    发明授权
    Process for the gelatin coating of medicaments 有权
    药物明胶包衣的方法

    公开(公告)号:US6126987A

    公开(公告)日:2000-10-03

    申请号:US274761

    申请日:1999-03-23

    摘要: A process and apparatus for the gelatin coating of medicaments which includes a continuous conveyer system to advance a plurality of pallets through a loading station, at least one dipping station, at least one dryer station, a reorientation station and an unloading station. Medicaments to be coated are loaded into pallets at the loading station and advanced to the first dipping station where a vacuum is applied to secure the medicament to the pallet. The pallet is inverted and a first portion of each of the medicaments is dipped into a coating mixture. The pallet is then returned to its upright position, the vacuum is removed and the coating is dried. The medicaments are then transferred from the first pallet to a second pallet by a reorientation mechanism. The second pallet is then advanced to a second dipping station which operates in the same manner as the first dipping station. The second pallet is advanced through the dryer station and the fully coated medicaments are ejected from the pallet into a container. The pallets used to hold the medicaments include a plate-like support member, on which rests a flexible mat having a rectangular array of receptacles including compliant diaphragm portions such that when a vacuum is applied to the pallet, the medicaments are secured thereto. The drying means includes air directing plates having sinusoidal rows of air directing apertures under which the medicaments to be dried are passed.

    摘要翻译: 用于药物明胶涂层的方法和装置,其包括连续输送系统,以通过装载站,至少一个浸渍站,至少一个干燥站,重新定向站和卸载站推进多个托盘。 待涂覆的药物装载在装载站的托盘中并且前进到第一浸渍站,在那里施加真空以将药剂固定到托盘上。 托盘倒置,每个药物的第一部分浸入涂料混合物中。 然后将托盘返回到其直立位置,除去真空并将涂层干燥。 然后通过重新定向机构将药物从第一托盘转移到第二托盘。 然后将第二托盘推进到以与第一浸渍站相同的方式操作的第二浸渍站。 第二个托盘通过干燥站前进,完全涂覆的药物从托盘中排出到容器中。 用于保持药物的托盘包括板状支撑构件,其上放置有具有矩形阵列的容器的柔性垫,其包括顺应性膜部分,使得当将真空施加到托盘时,药物被固定到其上。 干燥装置包括具有正弦排的空气引导孔的空气引导板,待干燥的药物在该空气引导孔下通过。

    Process and apparatus for holding medicaments to be coated
    2.
    发明授权
    Process and apparatus for holding medicaments to be coated 有权
    用于保持待涂药剂的方法和装置

    公开(公告)号:US06258400B1

    公开(公告)日:2001-07-10

    申请号:US09274759

    申请日:1999-03-23

    IPC分类号: A61J103

    摘要: A process and apparatus for holding a plurality of medicaments to be coated is disclosed. A support member is provided having a receiving surface with a plurality of channels to communicate a vacuum across the receiving surface and an aperture operable to couple the plurality of channels to a vacuum source. A flexible mat having a perimeter shaped to engage the support member in a sealed relation is provided on the support member. The flexible mat includes a plurality of medicament receptacles mounted to a first surface and adapted to receive the medicaments. The medicament receptacles initially are in a first position when no vacuum is applied. In the first position, the medicament receptacles are positioned to receive a medicament. When a vacuum is applied, the medicament receptacles change to a second position in which the medicament receptacles are positioned to hold the medicament and permit coating thereof.

    摘要翻译: 公开了一种用于保持待涂覆的多种药物的方法和装置。 提供了一种支撑构件,其具有接收表面,该接收表面具有多个通道以在接收表面上传递真空,以及可操作以将多个通道耦合到真空源的孔。 在支撑构件上设置有具有成形为以密封关系与支撑构件接合的周边的柔性垫。 柔性垫包括安装到第一表面并适于接收药物的多个药物容器。 当不施加真空时,药物容器最初处于第一位置。 在第一位置,药物容器被定位成容纳药物。 当施加真空时,药物容器改变到第二位置,在该第二位置,药物容器被定位成保持药物并允许其涂覆。

    Curtain coating method and apparatus using dual wire edge guides
    4.
    发明授权
    Curtain coating method and apparatus using dual wire edge guides 失效
    帘线涂布方法和使用双线边缘导轨的设备

    公开(公告)号:US5328726A

    公开(公告)日:1994-07-12

    申请号:US979504

    申请日:1992-11-19

    申请人: Thomas C. Reiter

    发明人: Thomas C. Reiter

    摘要: The present invention discloses edge guides (12) for use in guiding a curtain (17) of coating liquid onto a moving support. Each edge guide (12) is made of two or more small diameter wires (20) spaced apart a distance and running from the hopper lip (16) to the support web. The distance between the wires is approximately the thickness of the curtain. Flushing solution is introduced between the wires (20) near the hopper lip (16) and removed near the support web (15).

    摘要翻译: 本发明公开了一种用于将涂覆液体的帘幕(17)引导到移动的支撑件上的边缘引导件(12)。 每个边缘引导件(12)由两个或更多个间距距离的小直径的线(20)制成,并且从漏斗唇缘(16)延伸到支撑腹板。 电线之间的距离约为帘幕的厚度。 冲洗溶液引入靠近料斗唇缘(16)的线(20)之间,并在支撑腹板(15)附近被移除。

    Curtain coating method and apparatus
    5.
    发明授权
    Curtain coating method and apparatus 失效
    窗帘涂布方法及装置

    公开(公告)号:US4830887A

    公开(公告)日:1989-05-16

    申请号:US185207

    申请日:1988-04-22

    申请人: Thomas C. Reiter

    发明人: Thomas C. Reiter

    摘要: Method and apparatus for applying one or a plurality of superimposed layers of a photographic coating composition by the curtain coating method onto a moving support. The spacing between the edge guides, used to maintain the width of a curtain throughout its free fall from the coating hopper to the impingement line on the support, is arranged to coat less than the width of the support so as to provide an uncoated margin on the support. The curtain fluids are extracted from the edge region of the falling curtain by connecting a suction device to the edge guides near the point of impingement of the falling curtain, thus substantially reducing the thickness of the curtain at its edge region and thereby reducing the thickness of the coated edges.

    摘要翻译: 通过帘式涂布方法将一个或多个照相涂料组合物叠加层施加到移动载体上的方法和装置。 边缘引导件之间的间距用于将窗帘的宽度保持在从涂覆料斗自由落下到支撑件上的冲击线上,布置成小于支撑件的宽度以便提供未涂覆的边缘 支撑。 通过将抽吸装置连接到落下的帷幕撞击点附近的边缘导向器,帘幕流体从帷幕的边缘区域被抽出,从而大大减小了窗帘边缘区域的厚度,从而减小了帘幕的厚度 涂层边缘。

    Process and apparatus for drying a plurality of dip-coated medicaments
    6.
    发明授权
    Process and apparatus for drying a plurality of dip-coated medicaments 有权
    用于干燥多种浸涂药物的方法和设备

    公开(公告)号:US06195911B1

    公开(公告)日:2001-03-06

    申请号:US09274760

    申请日:1999-03-23

    IPC分类号: F26B300

    摘要: A process and apparatus for the gelatin coating of medicaments which includes a continuous conveyer system to advance a plurality of pallets through a loading station, at least one dipping station, at least one dryer station, a reorientation station and an unloading station. Medicaments to be coated are loaded into pallets at the loading station and advanced to the first dipping station where a vacuum is applied to secure the medicament to the pallet. The pallet is inverted and a first portion of each of the medicaments is dipped into a coating mixture. The pallet is then returned to its upright position, the vacuum is removed and the coating is dried. The medicaments are then transferred from the first pallet to a second pallet by a reorientation mechanism. The second pallet is then advanced to a second dipping station which operates in the same manner as the first dipping station. The second pallet is advanced through the dryer station and the fully coated medicaments are ejected from the pallet into a container. The pallets used to hold the medicaments include a plate-like support member, on which rests a flexible mat having a rectangular array of receptacles including compliant diaphragm portions such that when a vacuum is applied to the pallet, the medicaments are secured thereto. The drying means includes air directing plates having sinusoidal rows of air directing apertures under which the medicaments to be dried are passed.

    摘要翻译: 用于药物明胶涂层的方法和装置,其包括连续输送系统,以通过装载站,至少一个浸渍站,至少一个干燥站,重新定向站和卸载站推进多个托盘。 待涂覆的药物装载在装载站的托盘中并且前进到第一浸渍站,在那里施加真空以将药剂固定到托盘上。 托盘倒置,每个药物的第一部分浸入涂料混合物中。 然后将托盘返回到其直立位置,除去真空并将涂层干燥。 然后通过重新定向机构将药物从第一托盘转移到第二托盘。 然后将第二托盘推进到以与第一浸渍站相同的方式操作的第二浸渍站。 第二个托盘通过干燥站前进,完全涂覆的药物从托盘中排出到容器中。 用于保持药物的托盘包括板状支撑构件,其上放置有具有矩形阵列的容器的柔性垫,其包括顺应性膜部分,使得当将真空施加到托盘时,药物被固定到其上。 干燥装置包括具有正弦排的空气引导孔的空气引导板,待干燥的药物在该空气引导孔下通过。

    Apparatus for orienting and loading solid compact medicaments
    8.
    发明授权
    Apparatus for orienting and loading solid compact medicaments 失效
    用于定向和装载固体紧凑型药物的装置

    公开(公告)号:US5579951A

    公开(公告)日:1996-12-03

    申请号:US264391

    申请日:1994-06-23

    摘要: An apparatus (10) for orienting and loading solid compact medicaments, such as solid compact medicaments (A), into a carrier device (C) comprises a feeder (12) having a plurality of elongated first channels (20) through which the solid compact medicaments travel with an acute angle relative to a predetermined orientation of the carrier device (C). An orienting member (32) cooperating with the feeder (12) reorients the solid compact medicaments to the predetermined orientation as they exit the feeder (12). In an alternative embodiment, a pitch changing means (42) in fluid communications with the orienting means (32) provides for final orientation of the solid compact medicaments prior to loading in the carrier device (C).

    摘要翻译: 用于将固体致密药物(例如固体致密药物(A))定向和装载到载体装置(C)中的装置(10)包括具有多个细长的第一通道(20)的进料器(12),固体致密体 药物相对于载体装置(C)的预定方向以锐角行进。 与进料器(12)配合的取向件(32)在出口给料器(12)时将固体紧凑型药物重新定向至预定取向。 在替代实施例中,与定向装置(32)流体连通的间距改变装置(42)在装载到载体装置(C)之前提供固体紧凑型药物的最终取向。

    Apparatus for holding solid compact medicaments during coating processing
    9.
    发明授权
    Apparatus for holding solid compact medicaments during coating processing 失效
    用于在涂覆处理期间保持固体紧凑型药物的装置

    公开(公告)号:US5514216A

    公开(公告)日:1996-05-07

    申请号:US88500

    申请日:1993-07-07

    摘要: An apparatus for holding and subsequently releasing a solid compact medicament, such as a caplet. The apparatus has a first and a second member each having an upper and a lower surface. The first and second members each have at least one notch opposed to each other and correspondingly aligned and extending beyond the respective upper and lower surfaces of each member. The first and second members have chambers adjacent to each of the notches, and each of the notches is moveable in the respective chamber of the opposing member so that the opposing notches form a gripping jaw that can move between a first and a second position. When the gripping jaw is in an open first position, it can receive a solid compact medicament, and in a closed second position, the gripping jaw can grip the medicament.

    摘要翻译: 一种用于保持和随后释放固体致密药物的装置,例如囊片。 该装置具有分别具有上表面和下表面的第一和第二构件。 第一和第二构件各自具有彼此相对的至少一个切口,并且相应地对准并延伸超过每个构件的相应的上表面和下表面。 第一和第二构件具有与每个凹口相邻的腔室,并且每个凹口可在相对构件的相应室中移动,使得相对的凹口形成可在第一和第二位置之间移动的夹爪。 当夹爪处于打开的第一位置时,其可以容纳固体紧凑的药物,并且在闭合的第二位置中,夹爪可夹持药物。

    Apparatus for holding solid compact medicaments during processing
    10.
    发明授权
    Apparatus for holding solid compact medicaments during processing 失效
    用于在加工过程中保持固体紧凑型药物的装置

    公开(公告)号:US5391230A

    公开(公告)日:1995-02-21

    申请号:US88467

    申请日:1993-07-07

    摘要: An apparatus for capturing and holding a solid compact medicament, such as a caplet, has first, second and third members each having a surface having at least one throughole therein. Througholes have a diameter somewhat greater than the thickness of the solid compact medicament and the interior wall of the througholes 1as an axial length smaller than the length of the solid compact medicament. First and third members are fixed relative to one another. Second member is displaceable between first and third members between a first position wherein the througholes in members are aligned thereby defining an open gripping jaw for receiving and subsequently releasing the solid compact medicament, to a second position wherein the second member firmly engages a circumferential portion of solid compact medicament thereby engagingly capturing solid compact medicament in partially closed gripping jaw for processing.

    摘要翻译: 用于捕获和保持固体紧凑药物(例如囊片)的装置具有第一,第二和第三构件,每个构件具有在其中具有至少一个通孔的表面。 排水孔的直径略大于固体紧凑型药物的厚度,并且导流孔1的内壁的轴向长度小于固体压实药物的长度。 第一和第三个成员是相对于彼此固定的。 第二构件可在第一位置和第三构件之间移动,第一位置和第二位置之间,其中,构件中的通孔对齐,从而限定用于接收和随后将固体致密药物释放的打开的夹爪,到第二位置,其中第二构件牢固地接合 固体压实药物,从而在部分闭合的夹爪中接合捕获固体致密药物用于加工。