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公开(公告)号:US20130095046A1
公开(公告)日:2013-04-18
申请号:US13441164
申请日:2012-04-06
IPC分类号: A61K36/324
CPC分类号: A61K36/324 , A61K8/361 , A61K8/4973 , A61K8/63 , A61K8/68 , A61K8/97 , A61K2800/75 , A61K2800/782 , A61Q17/00 , A61Q19/00 , A61Q19/007 , A61Q19/08
摘要: The invention relates to a method for improving skin lipid barrier function by applying to the skin a composition comprising effective amounts of a protease inhibitor and a cell differentiation enhancer. The composition is useful in promoting skin lipid barrier repair and maintaining the integrity of the lipid barrier. In this regard, the compositions can be used in the treatment and prevention of dry skin, and associated chrono/proto-aging conditions, in the treatment and prevention of irritation on the skin, in the treatment and prevention of UV-related damage to the skin, and in the enhancement of the retention of self-tanning.
摘要翻译: 本发明涉及通过向皮肤施用包含有效量的蛋白酶抑制剂和细胞分化增强剂的组合物来改善皮肤脂质屏障功能的方法。 该组合物可用于促进皮肤脂质屏障修复并保持脂质屏障的完整性。 在这方面,组合物可以用于治疗和预防干性皮肤,以及相关的计时/原始老化条件,用于治疗和预防对皮肤的刺激,治疗和预防与紫外线相关的损伤 皮肤,并增强保持自鞣性。
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公开(公告)号:US08084496B2
公开(公告)日:2011-12-27
申请号:US12775206
申请日:2010-05-06
申请人: Daniel H. Maes , Fatemeh Mohammadi , Lisa Qu , Anna Czarnota , Thomas Mammone , Lieve Declercq , Julius R. Zecchino
发明人: Daniel H. Maes , Fatemeh Mohammadi , Lisa Qu , Anna Czarnota , Thomas Mammone , Lieve Declercq , Julius R. Zecchino
IPC分类号: A61K31/216 , A61K8/18 , A01N37/16
摘要: Resveratrol ferulate compounds and compositions.
摘要翻译: 白藜芦醇化合物和组合物。
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公开(公告)号:US20110223262A1
公开(公告)日:2011-09-15
申请号:US13114505
申请日:2011-05-24
申请人: George Cioca , Vasile Ionita-Manzatu , Liliana George , Paolo U. Giacomoni , Andrew J. Bevacqua , Harvey Gedeon , Charles Craig Tadlock , Donald F. Collins , Thomas Mammone , Daniel H. Maes , Christina G. Fthenakis
发明人: George Cioca , Vasile Ionita-Manzatu , Liliana George , Paolo U. Giacomoni , Andrew J. Bevacqua , Harvey Gedeon , Charles Craig Tadlock , Donald F. Collins , Thomas Mammone , Daniel H. Maes , Christina G. Fthenakis
CPC分类号: A61Q19/00 , A61K8/97 , A61K8/99 , A61K35/32 , A61K36/064 , A61K36/14 , A61K36/185 , A61K36/21 , A61K36/23 , A61K36/28 , A61K36/38 , A61K36/48 , A61K36/484 , A61K36/53 , A61K36/54 , A61K36/58 , A61K36/738 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/896 , A61K36/9068 , A61K38/39 , A61K2800/28 , A61K2800/85 , A61K2300/00
摘要: The present invention relates to a method of modulating a selected biological activity of a naturally occurring material having one or more biological activities in an extract of the naturally occurring material, the method comprising incubating the extract in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to modulate the selected activity with respect to baseline activity of the unincubated extract. The invention also relates to the bioconverted material so prepared, and the use of same in cosmetic or pharmaceutical compositions.
摘要翻译: 本发明涉及在天然存在的材料的提取物中调节具有一种或多种生物活性的天然存在物质的选定生物活性的方法,所述方法包括在有氧代谢微生物存在下将培养基中的提取物 在合适的有氧条件下,足以调节相对于未温育的提取物的基线活性的选定活性的时间。 本发明还涉及如此制备的生物转化材料及其在化妆品或药物组合物中的用途。
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公开(公告)号:US20090047309A1
公开(公告)日:2009-02-19
申请号:US11837658
申请日:2007-08-13
申请人: Daniel H. Maes , Thomas Mammone , Kerri Goldgraben
发明人: Daniel H. Maes , Thomas Mammone , Kerri Goldgraben
CPC分类号: A61K31/70 , A61K8/347 , A61K8/37 , A61K8/55 , A61K8/66 , A61K38/465 , A61K38/47 , A61Q19/00 , A61Q19/08
摘要: The present invention relates to methods and compositions for repairing adverse effects of the environment, daily stress, sun exposure, or pre-mature aging on human skin, comprising applying to the skin, prior to a period of bodily rest, a topical composition that contains resveratrol or a derivative thereof and at least one DNA repair enzyme.
摘要翻译: 本发明涉及用于修复环境,日常压力,日晒暴露或对人皮肤的熟化前衰老的不利影响的方法和组合物,其包括在身体休息期之前将皮肤施用于含有 白藜芦醇或其衍生物和至少一种DNA修复酶。
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公开(公告)号:US20070154444A1
公开(公告)日:2007-07-05
申请号:US11322014
申请日:2005-12-29
摘要: The present invention relates to topical skin whitening compositions comprising a whitening effective amount of a black yeast-derived melanin-degrading enzyme extract and a method of preparing the compositions. The compositions provide a whitening effect by degrading melanin on the surface of the skin, the hair and the nails. The enzyme extract can be derived from Exophiala mansonii. The compositions containing the enzyme extract are more effective than are similar compositions containing kojic acid in producing a whitening effect on the skin.
摘要翻译: 本发明涉及包含增白有效量的黑酵母衍生的黑色素降解酶提取物的局部皮肤增白组合物和制备该组合物的方法。 该组合物通过降解皮肤表面,头发和指甲上的黑色素来提供美白效果。 酶提取物可以衍生自洋葱(Exophiala mansonii)。 含有酶提取物的组合物比含有曲酸的类似组合物在皮肤上产生美白效果方面更有效。
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公开(公告)号:US20060002871A1
公开(公告)日:2006-01-05
申请号:US11167390
申请日:2005-06-27
申请人: Mindy Goldstein , Chia Chen , Thomas Mammone , David Gan
发明人: Mindy Goldstein , Chia Chen , Thomas Mammone , David Gan
摘要: A cosmetic composition comprising a UV-protective amount of at least one rosavin, preferably present in an extract of Rhodiola rosea in a cosmetically acceptable vehicle, and methods of use thereof, including preventing or reducing the signs of photoaging.
摘要翻译: 化妆品组合物,其包含紫外线保护量的至少一种罗沙星,优选存在于化妆品可接受载体中的红景天提取物中,以及其使用方法,包括预防或减少光老化的迹象。
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公开(公告)号:US20140200508A1
公开(公告)日:2014-07-17
申请号:US13923972
申请日:2013-06-21
IPC分类号: A61M37/00
CPC分类号: A61M37/0015 , A45D34/04 , A61L31/042 , A61L31/141 , A61L31/148 , A61L31/16 , A61L2300/40 , A61L2300/62 , A61L2430/34 , A61M2037/0023 , A61M2037/0046 , A61M2037/0053 , A61M2037/0061
摘要: An applicator for applying cosmetic agents into human skin, comprising: (a) a base, (b) a plurality of microneedles fixed to said base and projecting therefrom a distance sufficient to penetrate into the skin, said microneedles being made of a material that is capable of disintegration and dispersion into the skin, and (c) a cosmetic agent carried by said microneedles for delivery by said microneedles into the skin.
摘要翻译: 一种用于将化妆剂施用于人体皮肤的涂抹器,包括:(a)基底,(b)固定到所述基底上的多个微针,并将其伸出足以穿透到皮肤中的距离,所述微针由 能够分解和分散到皮肤中,和(c)由所述微针携带的用于由所述微针输送到皮肤中的化妆品。
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公开(公告)号:US08461200B2
公开(公告)日:2013-06-11
申请号:US13294229
申请日:2011-11-11
申请人: Daniel H. Maes , Fatemeh Mohammadi , Lisa Qu , Anna Czarnota , Thomas Mammone , Lieve Declercq , Julius R. Zecchino
发明人: Daniel H. Maes , Fatemeh Mohammadi , Lisa Qu , Anna Czarnota , Thomas Mammone , Lieve Declercq , Julius R. Zecchino
IPC分类号: A61K31/216 , A61K8/37
CPC分类号: A61K8/375 , A61K8/0241 , A61K8/062 , A61K8/064 , A61K8/066 , A61K8/25 , A61K8/347 , A61K8/37 , A61K8/42 , A61K8/585 , A61K8/60 , A61K8/602 , A61K8/891 , A61K8/97 , A61K31/05 , A61K2800/31 , A61K2800/43 , A61K2800/54 , A61K2800/591 , A61K2800/596 , A61Q1/02 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q1/12 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/08 , C07C69/017 , C07C69/30 , C07C69/604 , C07C69/94
摘要: Salicylic acid esters of resveratrol and topical compositions containing same.
摘要翻译: 白藜芦醇的水杨酸酯和含有它们的局部组合物。
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公开(公告)号:US20100297042A1
公开(公告)日:2010-11-25
申请号:US12726043
申请日:2010-03-17
摘要: A cosmetic composition comprising a UV-protective amount of at least one rosavin, preferably present in an extract of Rhodiola rosea in a cosmetically acceptable vehicle, and methods of use thereof, including preventing or reducing the signs of photoaging.
摘要翻译: 化妆品组合物,其包含紫外线保护量的至少一种罗沙星,优选存在于化妆品可接受载体中的红景天提取物中,以及其使用方法,包括预防或减少光老化的迹象。
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公开(公告)号:US20100216879A1
公开(公告)日:2010-08-26
申请号:US12775206
申请日:2010-05-06
申请人: Daniel H. Maes , Fatemeh Mohammadi , Lisa Qu , Anna Czarnota , Thomas Mammone , Lieve Declercq , Julius R. Zecchino
发明人: Daniel H. Maes , Fatemeh Mohammadi , Lisa Qu , Anna Czarnota , Thomas Mammone , Lieve Declercq , Julius R. Zecchino
IPC分类号: A61K8/37 , C07C69/736 , A61Q19/00
摘要: Resveratrol ferulate compounds and compositions.
摘要翻译: 白藜芦醇化合物和组合物。
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