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公开(公告)号：US20220330879A1
公开(公告)日：2022-10-20
申请号：US17764887
申请日：2020-10-02
Applicant: Aldo FAISAL , Richard FESTENSTEIN , Valeria RICOTTI , Thomas VOIT
Inventor： Aldo Faisal , Richard Festenstein , Valeria Ricotti , Thomas Voit
IPC: A61B5/00 , C12Q1/6883 , A61B5/11 , G16H50/30 , G16H40/63
Abstract: A system for monitoring the state of a disease or the state of a person using a biomarker, the system comprising: a motion data obtaining unit configured to obtain from at least one motion sensor motion data from a person having the disease, a generating unit configured to generate a value of the biomarker of the disease based on the obtained motion data, and an assessing unit configured to assess the value of the biomarker of the disease and, based on the assessment, to output information related to the state of the disease or state of a person
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公开(公告)号：US09739704B2
公开(公告)日：2017-08-22
申请号：US13990692
申请日：2011-11-23
Applicant: Thomas Voit , Michael Geissler , Harald Quintel , Roman Gruler
Inventor： Thomas Voit , Michael Geissler , Harald Quintel , Roman Gruler
CPC classification number: G01N21/03 , B01L3/50825 , B01L2300/043 , B01L2300/047 , B01L2300/0654 , G01N21/0303 , G01N2021/0378 , G01N2021/6482 , G01N2201/066
Abstract: Fluid processing tube for use in optical analysis comprising at least one first portion being made from a first material suitable for optical analysis and being configured to include two optical paths of different lengths, and at least one second portion connected to said first portion and being made from a second material different from said first material.
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公开(公告)号：US09546112B2
公开(公告)日：2017-01-17
申请号：US13636596
申请日：2011-03-22
Applicant: Thomas Voit , Luis Garcia , Jérôme Denard , Fedor Svinartchouk
Inventor： Thomas Voit , Luis Garcia , Jérôme Denard , Fedor Svinartchouk
IPC: C12N15/00 , A61K35/12 , A61N1/30 , C04B35/10 , A61K38/17 , A61K38/21 , A61K45/06 , C07K16/08 , C07K16/18 , C12N15/86 , A61K31/522 , A61K38/00 , A61K48/00 , C04B35/14 , C04B35/565 , C04B35/622 , C07K14/005 , C12N7/00
CPC classification number: C04B35/10 , A61K31/522 , A61K38/00 , A61K38/1709 , A61K38/21 , A61K45/06 , A61K48/0008 , A61K48/0058 , C04B35/14 , C04B35/565 , C04B35/622 , C07K14/005 , C07K16/081 , C07K16/18 , C12N7/00 , C12N15/86 , C12N2750/14122 , C12N2750/14143 , C12N2750/14145 , C12N2750/14151 , C12N2810/6027 , A61K2300/00
Abstract: Methods for increasing the efficiency of target tissue penetration of an adeno-associated virus (AAV) vector in a patient are provided. In some aspects, the methods involve inhibiting the interaction of the serum protein galectin 3 binding protein (G3BP) with AAV vector. Further provided are methods for reducing tissue distribution of a virus or for neutralizing a virus harbored by an organ destined for transplant, or newly transplanted, by administering a composition comprising G3BP.
Abstract translation: 提供了增加患者中腺相关病毒（AAV）载体靶组织穿透效率的方法。 在某些方面，该方法涉及抑制血清蛋白半乳凝素3结合蛋白（G3BP）与AAV载体的相互作用。 进一步提供的是通过施用包含G3BP的组合物来减少病毒的组织分布或用于中和由待移植或新移植的器官所携带的病毒的方法。
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公开(公告)号：US20140056784A1
公开(公告)日：2014-02-27
申请号：US14003755
申请日：2012-03-09
Applicant: Daniel Simons , Dirk Leber , Harald Quintel , Sasa Lazevski , Bruno Walder , Andreas Bretscher , Thomas Voit
Inventor： Daniel Simons , Dirk Leber , Harald Quintel , Sasa Lazevski , Bruno Walder , Andreas Bretscher , Thomas Voit
IPC: B01L3/00
CPC classification number: B01L3/50825 , B01L2300/045 , B65D39/06
Abstract: The invention relates to a sample container, comprising a housing which forms a sample space for receiving a sample and has at least one circular opening which extends in a channel-shaped manner into the sample space, and further comprising a spherical closing element, wherein the diameter of the closing element only exceeds the diameter of the opening channel in at least one (closing) portion to such an extent that the closing element can be fixed in a force-locked manner by its largest circumference in the closing portion, wherein the spherical closing element is in contact with the housing, and the opening channel between the closing portion and the inner opening forms a protrusion which reduces the opening cross section of the opening channel with respect to the opening cross section in the closing portion.
Abstract translation: 本发明涉及一种样品容器，其包括壳体，其形成用于接收样品的样品空间，并且具有至少一个以通道形状延伸到样品空间中的圆形开口，并且还包括球形闭合元件，其中， 关闭元件的直径仅在至少一个（关闭）部分中超过开口通道的直径，使得闭合元件可以通过其在关闭部分中的最大圆周以锁定方式被固定，其中，球形 关闭元件与壳体接触，并且封闭部分和内部开口之间的开口通道形成一个突起，该突起减小了开口通道相对于封闭部分中的开口横截面的开口横截面。
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公开(公告)号：US08361217B2
公开(公告)日：2013-01-29
申请号：US12522829
申请日：2008-07-18
Applicant: Thomas Voit , Christian Schramm
Inventor： Thomas Voit , Christian Schramm
CPC classification number: C09D5/38 , C01P2002/72 , C01P2004/61 , C09C1/64
Abstract: The invention relates to metallic paint comprising water and/or organic solvent and also at least one film-forming agent, at least one organofunctional silane, and at least one metallic effect pigment, the metallic effect pigment being a leafing aluminum pigment.The invention also relates to a process for preparing the metallic paint of the invention, and its use. Also, furthermore, an article painted with the metallic paint of the invention, and a vehicle finish.
Abstract translation: 本发明涉及包含水和/或有机溶剂以及至少一种成膜剂，至少一种有机官能硅烷和至少一种金属效应颜料的金属涂料，该金属效果颜料是一种漂浮的铝颜料。 本发明还涉及本发明的金属涂料的制备方法及其用途。 此外，还有用本发明的金属涂料涂漆的物品和车辆表面。
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Patent Agency Ranking
公开(公告)号：US20110091364A1
公开(公告)日：2011-04-21
申请号：US12673755
申请日：2008-08-18
Applicant: Thomas Voit
Inventor： Thomas Voit
IPC: B01L3/00
CPC classification number: B65B69/0041 , B01L3/50853 , B01L2200/16 , B01L2300/044 , B01L2300/0672 , B01L2300/0832 , B65D77/08 , G01N35/1079
Abstract: A system (10) for removing a pipettable substance from a pre-filled container (20), which is closed off by a top (30) having at least one opening area (40), comprises an opening tool (100) having a tube (110), which has a cross-section corresponding substantially to the shape of the opening area and which comprises at a distal end (120) an endpiece (140) extending substantially obliquely relative to the longitudinal axis of the tube, which moves a part of the top (30) located inside the opening area (40) towards the container when the opening tool is applied, so as to form an opening in the top, and a point of attack (150) for a transporting tool (200). The opening tool (100) is designed to remain on the container (20) after use. Moreover, the system comprises a transporting tool (200) for moving the opening tool (100) through the lid, and a cannula (250), which is adapted to be inserted over at least part of its length through the tube (110) into the interior of the container (20), in the position of use of the opening tool (100), and one end of which can be connected to a suction device (300) for sucking a pipettable substance out of the interior of the container (20).
Abstract translation: 一种用于从预填充容器（20）中移除可移液物质的系统（10），其由具有至少一个开口区域（40）的顶部（30）封闭，包括具有管子的开口工具（100） （110），其横截面基本上对应于开口区域的形状，并且在远端（120）处包括相对于管的纵向轴线基本上倾斜地延伸的端部件（140），所述端件（110）移动部件 当打开工具被施加时，位于开口区域（40）内部的顶部（30）朝向容器移动，以便在顶部形成开口以及用于输送工具（200）的攻角（150）。 打开工具（100）设计成在使用后留在容器（20）上。 此外，该系统包括用于使打开工具（100）通过盖移动的输送工具（200）和套管（250），套管（250）适于在其长度的至少一部分上穿过管（110）插入， 所述容器（20）的内部处于使用所述打开工具（100）的位置，并且其一端可连接到用于从所述容器的内部吸出可移液物质的抽吸装置（300） 20）。
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公开(公告)号：US20100064938A1
公开(公告)日：2010-03-18
申请号：US12522829
申请日：2008-07-18
Applicant: Thomas Voit , Christian Schramm
Inventor： Thomas Voit , Christian Schramm
CPC classification number: C09D5/38 , C01P2002/72 , C01P2004/61 , C09C1/64
Abstract: The invention relates to metallic paint comprising water and/or organic solvent and also at least one film-forming agent, at least one organofunctional silane, and at least one metallic effect pigment, the metallic effect pigment being a leafing aluminum pigment.The invention also relates to a process for preparing the metallic paint of the invention, and its use. Also, furthermore, an article painted with the metallic paint of the invention, and a vehicle finish.
Abstract translation: 本发明涉及包含水和/或有机溶剂以及至少一种成膜剂，至少一种有机官能硅烷和至少一种金属效应颜料的金属涂料，该金属效果颜料是一种漂浮的铝颜料。 本发明还涉及本发明的金属涂料的制备方法及其用途。 此外，还有用本发明的金属涂料涂漆的物品和车辆表面。
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8.发明申请Cosmetic Composition For Obtaining A Cosmetic Coating With A Metallically Glossy Appearance, Artificial Fingernails And Use Of PVD Aluminum Pigments 审中-公开用于获得具有金属光泽外观的人造指甲和使用PVD铝颜料的化妆品涂料的化妆品组合物公开(公告)号：US20080131383A1
公开(公告)日：2008-06-05
申请号：US11792207
申请日：2006-07-26
Applicant: Peter Kruger , Thomas Voit
Inventor： Peter Kruger , Thomas Voit
CPC classification number: A61Q3/02 , A61K8/02 , A61K8/26 , A61K8/55 , A61K2800/43 , A61K2800/436
Abstract: The invention relates to a cosmetic composition comprising a liquid phase and a PVD aluminum pigment, wherein the cosmetic composition contains a PVD aluminum pigment at a pigmentation level of from 0.05 to 5.0% by weight, based on the total weight of the cosmetic composition, and at least one leafing additive. The invention further relates to an artificial fingernail and to the use of a PVD aluminum pigment.
Abstract translation: 本发明涉及包含液相和PVD铝颜料的化妆品组合物，其中所述化妆品组合物含有基于所述化妆品组合物的总重量为0.05-5.0重量％的着色剂水平的PVD铝颜料，以及 至少一种叶片添加剂。 本发明还涉及人造指甲和使用PVD铝颜料。
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公开(公告)号：US20230220421A1
公开(公告)日：2023-07-13
申请号：US18147821
申请日：2022-12-29
Applicant: Lucie CARRIER , Thomas ESCHENHAGEN , Thomas VOIT , Giulia MEARINI , Oliver MUELLER , Doreen STIMPEL
Inventor： Lucie CARRIER , Thomas ESCHENHAGEN , Thomas VOIT , Giulia MEARINI , Oliver MUELLER , Doreen STIMPEL , Julia MOUROT-FILIATRE
CPC classification number: C12N15/86 , C12N7/00 , C07K14/4716 , C12N5/0696 , A61K35/34 , C12N5/0657 , A61K48/0058 , C12N2830/008 , C12N2830/007 , C12N2799/025 , C12N2506/45 , C12N2750/14143
Abstract: The present invention relates to a gene therapy vector which is useful in the treatment or prevention of hypertrophic cardiomyopathy in a subject in need thereof. The gene therapy vector of the invention comprises a nucleic acid sequence encoding a cardiac sarcomeric protein and a cardiomyocyte-specific promoter which is operably linked to said nucleic acid sequence. The invention furthermore relates to a cell which comprises the gene therapy vector. Pharmaceutical compositions which comprise the gene therapy vector and/or a cell comprising said vector are also provided. In another aspect, the invention relates to a method for treating or preventing hypertrophic cardiomyopathy in a subject by introducing the gene therapy vector of the invention into a subject in need of treatment.
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公开(公告)号：US09080170B2
公开(公告)日：2015-07-14
申请号：US13635356
申请日：2011-03-17
Applicant: Luis Garcia , Denis Furling , Cyriaque Beley , Thomas Voit
Inventor： Luis Garcia , Denis Furling , Cyriaque Beley , Thomas Voit
CPC classification number: C12N15/111 , C12N2310/11 , C12N2310/531 , C12N2320/33 , C12N2320/34 , C12N2320/50 , C12N2330/51
Abstract: The present invention relates to a method to improve the activity of engineered U7 snRNAs used in the context of RNA-based therapeutics; particularly in exon skipping, exon inclusion, and mRNA eradication strategies. The resulting modified U7 snRNAs are useful for treating neuromuscular diseases, in particular Duchenne neuromuscular dystrophy, myotonic dystrophy DM1 and spinal muscular atrophy.
Abstract translation: 本发明涉及一种改善在基于RNA的疗法的上下文中使用的工程化U7 snRNA的活性的方法; 特别是在外显子跳跃，外显子包含和mRNA消除策略。 所得修饰的U7 snRNA可用于治疗神经肌肉疾病，特别是杜烯神经肌营养不良症，强直性营养不良DM1和脊髓性肌肉萎缩。
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