Thin profile conductor assembly for medical device leads
    1.
    发明授权
    Thin profile conductor assembly for medical device leads 有权
    用于医疗器械引线的薄型导体组件

    公开(公告)号:US09084883B2

    公开(公告)日:2015-07-21

    申请号:US12704939

    申请日:2010-02-12

    CPC classification number: A61N1/056 A61N1/086

    Abstract: A medical device lead includes a thin profile conductor assembly. A proximal connector includes a proximal end that is configured to couple the lead to a pulse generator. An insulative lead body extends distally from the proximal connector. The conductor assembly extends distally from the proximal end within the lead body and includes a non-conductive tubular core member that defines a lumen, an outer insulative layer, and a multilayer conductor between the tubular core member and the outer insulative layer. The multilayer conductor is electrically connected to the proximal connector and includes a first conductive layer adjacent to the tubular core member and a second conductive layer adjacent to the first conductive layer opposite the tubular core member. A conductivity of the second conductive layer is greater than a conductivity of the first conductive layer.

    Abstract translation: 医疗器械引线包括薄型导体组件。 近端连接器包括被配置为将引线耦合到脉冲发生器的近端。 绝缘引线体从近端连接器向远侧延伸。 导体组件从引线主体内的近端向远侧延伸,并且包括在管芯和外绝缘层之间限定内腔,外绝缘层和多层导体的非导电管状芯构件。 所述多层导体电连接到所述近端连接器,并且包括与所述管状芯部件相邻的第一导电层和与所述管状芯部件相对的所述第一导电层相邻的第二导电层。 第二导电层的导电率大于第一导电层的导电率。

    Medical devices having inorganic particle layers
    2.
    发明授权
    Medical devices having inorganic particle layers 有权
    具有无机颗粒层的医疗装置

    公开(公告)号:US08932346B2

    公开(公告)日:2015-01-13

    申请号:US12428775

    申请日:2009-04-23

    Abstract: An expandable medical device having a particle layer disposed over a reservoir containing a therapeutic agent. The particle layer has a first porosity when the medical device is in the unexpanded configuration and a second porosity when the medical device is in the expanded configuration. The particle layer comprises a plurality of micron-sized or nano-sized particles. In certain embodiments, the particles are not connected to each other, and as such, the different porosities are provided by changes in the spacing between the particles as the medical device is expanded/unexpanded. Also disclosed are medical devices having a particle layer, wherein the particle layer comprises a plurality of encapsulated particles, and methods of coating medical devices with particles.

    Abstract translation: 一种可膨胀医疗装置,其具有设置在含有治疗剂的贮器上的颗粒层。 当医疗装置处于未膨胀构型时,颗粒层具有第一孔隙度,并且当医疗装置处于膨胀构型时具有第二孔隙率。 颗粒层包含多个微米级或纳米尺寸的颗粒。 在某些实施方案中,颗粒彼此不连接,因此,当医疗装置膨胀/未膨胀时,由颗粒之间的间隔的变化提供不同的孔隙度。 还公开了具有颗粒层的医疗装置,其中所述颗粒层包含多个包封的颗粒,以及用颗粒涂覆医疗装置的方法。

    Medical devices and methods of making the same
    5.
    发明授权
    Medical devices and methods of making the same 失效
    医疗器械和制造方法

    公开(公告)号:US08071155B2

    公开(公告)日:2011-12-06

    申请号:US11122583

    申请日:2005-05-05

    CPC classification number: C03C8/00 A61L31/082

    Abstract: Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, a method includes diffusing a first element into a first portion of the medical device. The first element includes carbon, hydrogen, nitrogen, oxygen, or combinations thereof. The first portion includes a refractory material.

    Abstract translation: 公开了诸如支架的医疗装置和制造装置的方法。 在一些实施例中,一种方法包括将第一元件扩散到医疗装置的第一部分中。 第一元素包括碳,氢,氮,氧或它们的组合。 第一部分包括耐火材料。

    POROUS FIBER ELECTRODE COATING AND RELATED METHODS
    7.
    发明申请
    POROUS FIBER ELECTRODE COATING AND RELATED METHODS 有权
    多孔纤维电极涂层及相关方法

    公开(公告)号:US20100241204A1

    公开(公告)日:2010-09-23

    申请号:US12703544

    申请日:2010-02-10

    CPC classification number: A61N1/056 A61B5/042 A61B2562/0209

    Abstract: The embodiments herein relate to an electrode having a porous coating including a fiber mesh, a multi-layer coating, and an outer coating, and a method of making the same. The various electrode coating embodiments include pores in the coating that prevent access by protein or cells while allowing for ion and/or liquid access.

    Abstract translation: 本文的实施方案涉及具有包括纤维网,多层涂层和外涂层的多孔涂层的电极及其制造方法。 各种电极涂覆实施方案包括涂层中的孔,其阻止蛋白质或细胞进入,同时允许离子和/或液体进入。

    Medical Devices Having Inorganic Barrier Coatings
    9.
    发明申请
    Medical Devices Having Inorganic Barrier Coatings 有权
    具有无机屏障涂层的医疗器械

    公开(公告)号:US20100021523A1

    公开(公告)日:2010-01-28

    申请号:US12501671

    申请日:2009-07-13

    Abstract: Medical devices having a barrier layer comprising an inorganic material. The medical device has a reservoir containing a therapeutic agent and the barrier layer is disposed over the reservoir. In one aspect, the barrier layer has one permeability to the therapeutic agent at one portion of the medical device and a different permeability at another portion of the medical device. In another aspect, the dosage amount of the therapeutic agent in the reservoir at one portion of the medical device is different from the dosage amount of the therapeutic agent in the reservoir at another portion of the medical device. In another aspect, a bioresorbable layer is disposed over the barrier layer at one or more portions of the medical device, wherein the bioresorbable layer comprises a bioresorbable material. Also, methods of coating a medical device are disclosed, in which a barrier layer over a medical device is formed using a lithographic etching process where a plurality of particles serve as an etch mask.

    Abstract translation: 具有包含无机材料的阻挡层的医疗装置。 医疗装置具有含有治疗剂的储液器,并且阻挡层设置在贮存器的上方。 在一个方面,阻挡层在医疗装置的一部分处具有对治疗剂的一种渗透性,并且在医疗装置的另一部分具有不同的渗透性。 另一方面,医疗器械的一部分处的储存器中的治疗剂的剂量与医疗器械的另一部分处的储存器中的治疗剂的剂量不同。 在另一方面,生物可再吸收层设置在医疗装置的一个或多个部分的阻挡层之上,其中生物可再吸收层包括生物可再吸收材料。 此外,公开了涂覆医疗装置的方法,其中使用光刻蚀刻工艺形成医疗装置上的阻挡层,其中多个颗粒用作蚀刻掩模。

    Primarily niobium stent
    10.
    发明授权
    Primarily niobium stent 失效
    主要是铌支架

    公开(公告)号:US07604703B2

    公开(公告)日:2009-10-20

    申请号:US11417856

    申请日:2006-05-03

    Abstract: In a process of fabricating a stent composed primarily of niobium alloyed with a trace amount of zirconium, tantalum, or titanium for hardening, the stent is annealed under vacuum in a substantially oxygen-free environment. The vacuum is preferably maintained at pressure less than 10−4 millibars, oxygen-content less than about 80 parts per million, and the annealing temperature exceeds 400° C. for at least one hour, and is preferably kept in a range from about 1100-1200° C. for several hours. This may be followed by applying a surface layer of oxide, such as iridium oxide, with a thickness of 299-300 nm to the stent.

    Abstract translation: 在制造主要由铌合金化的用于硬化的锆,钽或钛的支架的制造过程中,支架在基本上无氧的环境中在真空下退火。 真空优选保持在小于10-4毫巴的压力,含氧量小于约百万分之八十,退火温度超过400℃至少一小时,优选保持在约1100 -1200℃几个小时。 然后可以向支架施加厚度为299-300nm的氧化物表面层,例如氧化铱。

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