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    Powder inhalator
    1.
    发明授权
    Powder inhalator 失效
    粉末吸入器

    公开(公告)号：US08235039B2

    公开(公告)日：2012-08-07

    申请号：US11401938

    申请日：2006-04-12

    申请人： Toru Nishibayashi ,  Shintaro Adachi ,  Tetsuya Sato

    发明人： Toru Nishibayashi ,  Shintaro Adachi ,  Tetsuya Sato

    IPC分类号： B05D7/14 ,  A61M15/00

    CPC分类号： A61M15/0065 ,  A61M11/002 ,  A61M15/0025 ,  A61M15/0068 ,  A61M15/0075 ,  A61M2202/064 ,  A61M2205/0233 ,  A61M2206/16

    摘要： A powder inhalator including: a housing, a supply member for holding a powdered drug for a large number of doses and having a drug discharge aperture at its bottom surface; a drug carrier, to which the powdered drug is supplied from the drug discharge aperture of the supply member, and having on its upper surface a measuring recess that has a volume equivalent to one dose of the drug; and an operation member disposed so as to move freely back and forth, and operate the drug carrier; the drug carrier moving in contact with the bottom surface of the supply member to carry the powdered drug loaded into the measuring recess from the position of the drug discharge aperture to an air inhalation channel, wherein the drug carrier is disposed slidably so that the measuring recess moves in a circular manner by sliding the drug carrier.

    摘要翻译： 一种粉末吸入器，包括：壳体，用于保持大量剂量的粉末药物并在其底表面具有药物排放孔的供应构件; 药物载体，粉末药物从供给构件的药物排出口供给到药物载体上，并且在其上表面上具有相当于一剂药物的体积的测量凹部; 以及操作构件，其被设置成能够自由地前后移动，并且操作所述药物载体; 所述药物载体与所述供应构件的底表面接触移动，以将装载到所述测量凹部中的所述粉末药物从所述药物排放孔的位置运送到空气吸入通道，其中所述药物载体可滑动地设置，使得所述测量凹部 通过滑动药物载体以圆形方式移动。

    Disinfectant and/or bactericidal aqueous compositions
    2.
    发明申请
    Disinfectant and/or bactericidal aqueous compositions 审中-公开
    消毒剂和/或杀菌水性组合物

    公开(公告)号：US20070053942A1

    公开(公告)日：2007-03-08

    申请号：US10557747

    申请日：2004-05-25

    申请人： Toru Nishibayashi ,  Tetsuya Sato ,  Masaaki Odomi ,  Kinue Ohguro ,  Hiroshi Ishikawa

    发明人： Toru Nishibayashi ,  Tetsuya Sato ,  Masaaki Odomi ,  Kinue Ohguro ,  Hiroshi Ishikawa

    IPC分类号： A01N43/04 ,  A01N37/30 ,  A01N25/00

    CPC分类号： A61K31/155 ,  A01N47/44 ,  A01N25/30 ,  A01N2300/00

    摘要： The present invention provides a disinfectant and/or bactericidal aqueous composition containing an olanexidine acid addition salt, and at least one polyoxyethylene-based nonionic surfactant selected from the group consisting of polyoxyethylene higher alkyl ethers and polyoxyethylene alkylphenyl ethers; a disinfectant and/or bactericidal aqueous composition containing an olanexidine acid addition salt at a concentration of 0.05 to 0.5 W/V %, and an alcohol at a concentration of 20 to 80 W/V %, and not containing any surfactants; and a disinfectant and/or bactericidal aqueous composition containing an olanexidine acid addition salt, and at least one member selected from the group consisting of ester-based nonionic surfactants and cyclic oligosaccharides.

    摘要翻译： 本发明提供一种含有奥拉西酸加成盐的消毒剂和/或杀菌水性组合物，以及选自聚氧乙烯高级烷基醚和聚氧乙烯烷基苯基醚的至少一种聚氧乙烯基非离子表面活性剂; 含有浓度为0.05〜0.5W / V％的奥兰西酸加成盐的消毒剂和/或杀菌水性组合物，浓度为20〜80W / V％的醇，不含任何表面活性剂; 以及含有奥拉西酸加成盐的消毒剂和/或杀菌性水性组合物，以及选自酯类非离子表面活性剂和环状低聚糖中的至少一种。

    Particulate preparation containing a flourracil derivative and hydroxypropylmethyl-cellulose
    4.
    发明授权
    Particulate preparation containing a flourracil derivative and hydroxypropylmethyl-cellulose 失效
    含有粉状紫胶衍生物和羟丙基甲基纤维素的颗粒制剂

    公开(公告)号：US5316773A

    公开(公告)日：1994-05-31

    申请号：US842195

    申请日：1992-03-16

    申请人： Toru Nishibayashi ,  Yoshihiro Ishizue ,  Kozo Ishida ,  Masanori Kubo

    发明人： Toru Nishibayashi ,  Yoshihiro Ishizue ,  Kozo Ishida ,  Masanori Kubo

    IPC分类号： A61K9/14 ,  A61K9/16 ,  A61K31/505 ,  A61K47/38

    CPC分类号： A61K9/146 ,  A61K31/505

    摘要： The solid preparation of the invention is prepared by dissolving 3-[3-(6-Benzoyloxy-3-cyano-2-pyridyloxycarbonyl)benzoyl]-1-ethoxymethyl-5-fluorouracil (hereinafter referred to as "BOF-A2") and a water-soluble polymer in a organic solvent completely, followed by forming preparation of amorphous powder prepared by removing the organic solvent.The solid preparation is useful to enhance solubility of BOF-A2 and to accomplish rapid absorption of BOF-A2 through the alimentary canal.

    摘要翻译： PCT No.PCT / JP91 / 00951 Sec。 371日期：1992年3月16日 102（e）1992年3月16日PCT PCT 1991年7月17日PCT公布。 出版物WO92 / 01453 日本1992年2月6日。本发明的固体制剂通过将3- [3-（6-苯甲酰氧基-3-氰基-2-吡啶氧基羰基）苯甲酰基] -1-乙氧基甲基-5-氟尿嘧啶（以下称为 “BOF-A2”）和有机溶剂中的水溶性聚合物，然后形成通过除去有机溶剂制备的无定形粉末的制备。 固体制剂有助于提高BOF-A2的溶解度，并通过消化道快速吸收BOF-A2。

    Powder inhaler
    5.
    发明授权
    Powder inhaler 有权
    粉末吸入器

    公开(公告)号：US08875703B2

    公开(公告)日：2014-11-04

    申请号：US12994064

    申请日：2009-05-22

    申请人： Tetsuya Sato ,  Toru Nishibayashi ,  Yusuke Ogawa ,  Takaaki Nakao ,  Shintaro Adachi

    发明人： Tetsuya Sato ,  Toru Nishibayashi ,  Yusuke Ogawa ,  Takaaki Nakao ,  Shintaro Adachi

    IPC分类号： B05D7/14 ,  A61M15/00 ,  A61M11/00

    CPC分类号： A61M15/0065 ,  A61M11/002 ,  A61M15/0026 ,  A61M15/0075 ,  A61M2202/064

    摘要： A powder inhaler includes: a housing having a port; a storage member located in the housing for storing a powder medicament; and a medicament-delivery member provided in the housing. The medicament-delivery member includes at least one concave portion for receiving medicament, and is capable of taking, relative to the storage member, a receiving position wherein the concave portion receives a predetermined amount of powder medicament from the storage member, and an inhalation position wherein the powder medicament can be inhaled through the admission port; and a stirring member for stirring the powder medicament stored in the storage member. An operation button is provided in the housing and is capable of moving between the initial position and a depressed position, while the operation button reciprocates between the initial position and the depressed position, the concave portion in the medicament-delivery member moves from the receiving position to the inhalation position and the stirring member operates.

    摘要翻译： 粉末吸入器包括：具有端口的壳体; 位于所述壳体中的用于储存粉末药物的存储构件; 以及设置在所述壳体中的药物输送构件。 所述药物输送构件包括至少一个用于接收药物的凹部，并且能够相对于所述存储构件获取接收位置，其中所述凹部从所述存储构件接收预定量的粉末药物，并且吸入位置 其中所述粉末药物可以通过所述入口口吸入; 以及用于搅拌存储在所述存储部件中的粉末药剂的搅拌部件。 操作按钮设置在壳体中，并且能够在初始位置和踩下位置之间移动，同时操作按钮在初始位置和踩下位置之间往复运动，药物输送构件中的凹部从接收位置移动 到吸入位置并且搅拌部件工作。

    Powder inhaler
    9.
    发明授权
    Powder inhaler 失效
    粉末吸入器

    公开(公告)号：US08251059B2

    公开(公告)日：2012-08-28

    申请号：US12305273

    申请日：2007-06-26

    申请人： Toru Nishibayashi ,  Shintaro Adachi ,  Tetsuya Sato ,  Takaaki Nakao

    发明人： Toru Nishibayashi ,  Shintaro Adachi ,  Tetsuya Sato ,  Takaaki Nakao

    IPC分类号： A61M15/00 ,  A61M15/08 ,  A61M16/00 ,  B05D7/14 ,  B65D83/06

    CPC分类号： A61M15/0065 ,  A61M15/0005 ,  A61M15/0026 ,  A61M2202/064 ,  A61M2206/14

    摘要： The subject invention provides a powder inhaler enabling the user to complete powder drug inhalation with fewer steps, for improved user convenience.A powder inhaler of the present invention comprises: a housing 1A having an admission port 2f on one end; a supplier having a drug-discharging hole, provided inside the housing 1A with a capacity sufficient to contain plural doses of a fine powder drug; a drug carrier having a measurement concave portion for receiving a single dose of a drug from the drug-discharging hole, the drug carrier being supported inside the housing 1A while being movable between a drug-receiving position for allowing drug supply from the drug-discharging hole to the measurement concave portion, and a drug-inhalation position for allowing drug inhalation from the measurement concave portion through the admission port; a cover cap C2 pivotably mounted to the housing 1A; and a vibrating means 60 brought into operation by pivoting the cover cap C2 so as to vibrate the supplier.

    摘要翻译： 本发明提供一种粉末吸入器，使得使用者能够以更少的步骤完成粉末药物吸入，从而提高使用者的便利性。 本发明的粉末吸入器包括：壳体1A，其一端具有入口2f; 具有药物排出孔的供应商，其设置在壳体1A的内部，其容量足以容纳多个剂量的细粉末药物; 具有用于从药物排出孔接收单次药物的测量凹部的药物载体，药物载体被支撑在壳体1A内部，同时可在药物接收位置之间移动，以允许药物从药物排出口 和测量凹部的孔，以及药物吸入位置，用于允许药物从测量凹部通过入口吸入; 可枢转地安装到壳体1A的盖帽C2; 并且振动装置60通过使盖帽C2枢转而使供应商振动。