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公开(公告)号：US09409012B2
公开(公告)日：2016-08-09
申请号：US12484769
申请日：2009-06-15
IPC分类号： A61N1/375 , A61N1/05 , A61B17/3207 , A61N1/362 , A61B17/22
CPC分类号： A61N1/056 , A61B17/320725 , A61B2017/22061 , A61N1/362 , A61N1/3758
摘要： Cardioprotective pacing is applied to prevent and/or reduce cardiac injury associated with myocardial infarction (MI) and revascularization procedure. Pacing pulses are generated from a flexible pacemaker circuit integrated with a percutaneous transluminal vascular intervention (PTVI) device and delivered through pacing electrodes incorporated onto the PTVI device during the revascularization procedure.
摘要翻译： 心脏保护起搏应用于预防和/或减少与心肌梗塞（MI）和血运重建术相关的心脏损伤。 起搏脉冲从与经皮腔内血管介入（PTVI）装置集成的柔性起搏器电路产生，并且在血运重建过程期间通过并入PTVI装置的起搏电极递送。
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公开(公告)号：US08516871B2
公开(公告)日：2013-08-27
申请号：US12987587
申请日：2011-01-10
申请人： Jan Weber , Tracee Eidenschink
发明人： Jan Weber , Tracee Eidenschink
IPC分类号： B21D39/00
CPC分类号： A61F2/958 , A61F2002/9522 , B25B27/10 , Y10T29/49913 , Y10T29/49925 , Y10T29/53065 , Y10T29/53652 , Y10T29/53987 , Y10T29/53996
摘要： In one embodiment, an apparatus for shaping an article may comprise a plurality of movable dies arranged to form a chamber whose size may be varied by moving the dies. Each of the dies may have a contacting surface for contacting the article to be shaped. The chamber may have a first portion having a first cross-section and a second portion having a second cross-section. Either portion may include a taper. The first portion may have a differently shaped cross-section than the second portion. The first portion may have a cross-section of greater area than the second portion. The longitudinal axis of the first portion may be offset from the longitudinal axis of the second portion.
摘要翻译： 在一个实施例中，用于成型物品的装置可以包括多个可移动模具，其被设置成形成其尺寸可以通过移动模具而改变的腔室。 每个模具可以具有用于接触待成形制品的接触表面。 腔室可以具有第一部分和第二部分，第一部分具有第一横截面，第二部分具有第二横截面。 任一部分可以包括锥形。 第一部分可以具有与第二部分不同的形状的横截面。 第一部分可以具有比第二部分更大的面积的横截面。 第一部分的纵向轴线可以偏离第二部分的纵向轴线。
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公开(公告)号：US08414632B2
公开(公告)日：2013-04-09
申请号：US11368927
申请日：2006-03-06
申请人： Angela Kornkven Volk , Karl A. Jagger , Tracee Eidenschink , Richard Olson , John Blix , Derek Sutermeister , Jay Rassat
发明人： Angela Kornkven Volk , Karl A. Jagger , Tracee Eidenschink , Richard Olson , John Blix , Derek Sutermeister , Jay Rassat
CPC分类号： A61M25/001 , A61B2017/00398 , A61B2017/00871 , A61M25/0069 , A61M25/0074 , A61M25/10 , A61M2025/0024 , A61M2025/0058 , A61M2025/0063 , A61M2025/09125
摘要： A catheter tip has an outer surface section, an inner surface section, a spatial configuration and at least one segment of electroactive polymer. The inner surface section defines a guide wire lumen. The electroactive polymer has an actuated state and a non-actuated state. In an actuated state, the electroactive polymer alters the spatial configuration of the catheter tip.
摘要翻译： 导管尖端具有外表面部分，内表面部分，空间构造和至少一个电活性聚合物部分。 内表面部分限定导丝管腔。 电活性聚合物具有致动状态和非致动状态。 在致动状态下，电活性聚合物改变导管尖端的空间构型。
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公开(公告)号：US08398693B2
公开(公告)日：2013-03-19
申请号：US10763825
申请日：2004-01-23
申请人： Jan Weber , Tracee Eidenschink , David Elizondo , Loren Simer
发明人： Jan Weber , Tracee Eidenschink , David Elizondo , Loren Simer
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61B17/1214 , A61B17/320725 , A61B2017/00398 , A61B2017/00871 , A61B2017/22061 , A61F2/962 , A61M25/0054 , A61M25/0158 , A61M2025/0058 , A61N1/20
摘要： The present invention relates to medical devices for implantation or insertion into body lumens, for example, catheters, guidewires, stents and aneurysm coils. The devices of the present invention comprise electrically actuated materials, such as electroactive polymers and piezoelectric and electrostrictive materials, which enhance or expand their functionality.
摘要翻译： 本发明涉及用于植入或插入体腔的医疗装置，例如导管，导线，支架和动脉瘤线圈。 本发明的装置包括电致动材料，例如电活性聚合物和压电和电致伸缩材料，其增强或扩大它们的功能。
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公开(公告)号：US08348991B2
公开(公告)日：2013-01-08
申请号：US11755592
申请日：2007-05-30
申请人： Jan Weber , Karl A. Jagger , Tracee Eidenschink , James Anderson
发明人： Jan Weber , Karl A. Jagger , Tracee Eidenschink , James Anderson
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2002/30322 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2002/91583 , A61F2250/0018 , A61F2250/0026
摘要： A stent can comprise a tubular body having a first region and a second region. The tubular body is defined by a plurality of serpentine bands. Each serpentine band comprises a plurality of alternating proximal turns and distal turns connected by struts. The second region comprises a first serpentine band and a second serpentine band that overlap one another about a common stent circumference. The first region comprises a serpentine band that is not overlapped by another serpentine band about a common stent circumference.
摘要翻译： 支架可以包括具有第一区域和第二区域的管状体。 管状体由多个蛇形带限定。 每个蛇形带包括通过支柱连接的多个交替的近端匝和远端匝。 第二区域包括围绕公共支架圆周彼此重叠的第一蛇形带和第二蛇形带。 第一区域包括蛇形带，其不与另一个蛇形带围绕公共支架圆周重叠。
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6.发明申请ADJUSTABLE BIFURCATION CATHETER INCORPORATING ELECTROACTIVE POLYMER AND METHODS OF MAKING AND USING THE SAME 失效包含电动聚合物的可调节分支导管及其制造和使用方法公开(公告)号：US20120265286A1
公开(公告)日：2012-10-18
申请号：US13530400
申请日：2012-06-22
CPC分类号： A61M25/10 , A61F2/958 , A61M25/0158 , A61M25/1027 , A61M2025/0058 , A61M2025/1045 , A61M2025/1088
摘要： A medical device having at least one static state, at least one activated state, and at least one active region including electroactive polymer (EAP) capable of fine electro-activated movements. The EAP movements include bending components for proper alignment, rotating components for proper fittings, making components more rigid or flexible, and increasing and decreasing the volume of components. The fine movements allow for highly versatile and adaptable medical devices.
摘要翻译： 具有至少一种静态，至少一种活化状态和至少一种活性区域的医疗装置，所述活性区域包括能够精细电活化运动的电活性聚合物（EAP）。 EAP运动包括用于正确对准的弯曲部件，用于适当配件的旋转部件，使部件更加刚性或柔性，以及增加和减少部件的体积。 精细的动作允许高度通用和适应性强的医疗设备。
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7.发明授权Medical devices employing conductive polymers for delivery of therapeutic agents 有权使用导电聚合物递送治疗剂的医疗装置公开(公告)号：US08275455B2
公开(公告)日：2012-09-25
申请号：US12487203
申请日：2009-06-18
IPC分类号： A61N1/30
CPC分类号： A61M25/1029 , A61F2002/0081 , A61F2250/0068 , A61K9/0009 , A61K31/00 , A61K31/337 , A61K31/4745 , A61K31/52 , A61L27/50 , A61L27/54 , A61L29/14 , A61L29/16 , A61L2300/416 , A61L2300/602 , A61M25/10 , A61M25/104 , A61M2025/0057 , A61M2025/0058 , A61M2025/1031 , A61M2025/105 , A61M2025/1086 , A61M2025/1088 , A61M2025/1093
摘要： In accordance with one aspect, the invention relates to medical devices which comprise at least one reservoir, a therapeutic-agent-containing region disposed within the reservoir and an electrode comprising a conductive polymer. The devices of the invention are configured such that a rate of release of the therapeutic agent from the reservoir changes upon a change in the oxidation state of the conductive polymer.
摘要翻译： 根据一个方面，本发明涉及包括至少一个贮存器，设置在储存器内的含治疗剂的区域和包含导电聚合物的电极的医疗装置。 本发明的装置被配置成使得治疗剂从贮存器释放的速率随着导电聚合物的氧化态的变化而变化。
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8.发明申请Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface 审中-公开支架设计允许药物的扩展释放和/或增强的聚合物粘附到OD表面公开(公告)号：US20110282433A1
公开(公告)日：2011-11-17
申请号：US13189152
申请日：2011-07-22
申请人： Jan Weber , Tracee Eidenschink
发明人： Jan Weber , Tracee Eidenschink
IPC分类号： A61F2/84
CPC分类号： A61F2/91 , A61F2210/0076 , A61F2220/0066 , A61F2220/0083 , A61F2250/0067 , A61F2250/0068
摘要： The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields.
摘要翻译： 本发明涉及减少治疗剂从支架分层的机制和方法。 这些机构包括孔（通道，孔和其他孔构造），突起，烧结金属芯，夹/钉，销和不锈钢屏蔽。
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公开(公告)号：US07963940B2
公开(公告)日：2011-06-21
申请号：US11208879
申请日：2005-08-22
申请人： Thomas J. Holman , Jan Weber , Tracee Eidenschink
发明人： Thomas J. Holman , Jan Weber , Tracee Eidenschink
IPC分类号： A61M29/00
CPC分类号： A61F7/12 , A61F2007/0063 , A61F2007/126
摘要： A device for providing a fluid to a target tissue region of a body vessel is described. The device includes an elongate member having a lumen to receive a fluid, and a structure deployable from a distal portion of the elongate member to channel blood flowing in the vessel. Also described are a method of, and a system for, providing a fluid to a target tissue region inside a body.
摘要翻译： 描述了一种用于向身体血管的靶组织区域提供流体的装置。 该装置包括具有用于容纳流体的内腔的细长构件，以及可从细长构件的远侧部分展开以使在血管中流动的血液通道的结构。 还描述了向身体内的靶组织区域提供流体的方法和系统。
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公开(公告)号：US07886569B2
公开(公告)日：2011-02-15
申请号：US12510807
申请日：2009-07-28
申请人： Jan Weber , Tracee Eidenschink
发明人： Jan Weber , Tracee Eidenschink
CPC分类号： A61F2/958 , A61F2002/9522 , B25B27/10 , Y10T29/49913 , Y10T29/49925 , Y10T29/53065 , Y10T29/53652 , Y10T29/53987 , Y10T29/53996
摘要： In one embodiment, an apparatus for shaping an article may comprise a plurality of movable dies arranged to form a chamber whose size may be varied by moving the dies. Each of the dies may have a contacting surface for contacting the article to be shaped. The chamber may have a first portion having a first cross-section and a second portion having a second cross-section. Either portion may include a taper. The first portion may have a differently shaped cross-section than the second portion. The first portion may have a cross-section of greater area than the second portion. The longitudinal axis of the first portion may be offset from the longitudinal axis of the second portion.
摘要翻译： 在一个实施例中，用于成型物品的装置可以包括多个可移动模具，其被设置成形成其尺寸可以通过移动模具而改变的腔室。 每个模具可以具有用于接触待成形制品的接触表面。 腔室可以具有第一部分和第二部分，第一部分具有第一横截面，第二部分具有第二横截面。 任一部分可以包括锥形。 第一部分可以具有与第二部分不同的形状的横截面。 第一部分可以具有比第二部分更大的面积的横截面。 第一部分的纵向轴线可以偏离第二部分的纵向轴线。
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