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    Method for detecting and excising nonpalpable lesions
    7.
    发明授权
    Method for detecting and excising nonpalpable lesions 失效
    检测和切除不可触及的病变的方法

    公开(公告)号：US06714808B2

    公开(公告)日：2004-03-30

    申请号：US09970456

    申请日：2001-10-03

    申请人： V. Suzanne Klimberg ,  Steven E. Harms ,  Sohelia Korourian

    发明人： V. Suzanne Klimberg ,  Steven E. Harms ,  Sohelia Korourian

    IPC分类号： A61B5055

    CPC分类号： A61B90/39 ,  A61B10/0233 ,  A61B2090/374 ,  A61B2090/378 ,  A61B2090/3908

    摘要： A novel method of hematoma-directed ultrasound guided excisional breast biopsy is disclosed. In one aspect of the inventon, the hematoma is produced by an injection of the patient's own blood into a pre-selected area to target a lesion. Detection of the targeted lesion and hematoma is achieved with MRI. In a second aspect of the invention, the hematoma is produced by stereotactic core needle breast biopsy in a pre-selected area, and the targeted lesion and hematoma are detected using intraoperative ultrasound. The method avoids many of the disadvantages associated with traditional needle localized breast biopsy. The method can also be used to guide the excision of lesions visualized by MRI, ultrasound, mammography, PET scanning, and scintimammography. The method may be used in any organ and, in particular, the breast.

    摘要翻译： 公开了一种血肿导向超声引导切除乳腺活检的新方法。 在本发明的一个方面，血肿是通过将患者自己的血液注射到预选区域来靶向病变而产生的。 用MRI检测目标病变和血肿。 在本发明的第二方面中，通过在预选区域中的立体定向核心针乳房活检产生血肿，并且使用术中超声检测靶向病变和血肿。 该方法避免了与传统针定位乳腺活检相关的许多缺点。 该方法还可用于指导通过MRI，超声，乳房X线照相术，PET扫描和闪烁扫描显像的病变切除。 该方法可用于任何器官，特别是乳房。

    Minimally invasive diagnosis and treatment for breast cancer
    9.
    发明授权
    Minimally invasive diagnosis and treatment for breast cancer 有权
    乳腺癌的微创诊断和治疗

    公开(公告)号：US07769432B2

    公开(公告)日：2010-08-03

    申请号：US10866913

    申请日：2004-06-14

    申请人： V. Suzanne Klimberg ,  Sohelia Korourian ,  Steven Harms ,  Gal Shafirstein

    发明人： V. Suzanne Klimberg ,  Sohelia Korourian ,  Steven Harms ,  Gal Shafirstein

    IPC分类号： A61B6/00 ,  A61B8/00

    CPC分类号： A61B10/0233 ,  A61B10/0041 ,  A61B10/0283 ,  A61B2017/008 ,  A61B2018/2005 ,  A61B2090/374

    摘要： The present invention provides a treatment method to excise a cancerous lesion, such as in the breast, with subsequent ablation of the margin. The method provides for location and excision with ablation under open guidance or guided imaging and for diagnosis by cytology. The method may be a minimally, invasive same day method with diagnosis before or immediately after excision. Also provided is a method of treating close or positive margins of an excisional site of a cancerous lesion in a breast by ablating the margin while monitoring the fluorescence of a fluorophor at the site to determine when ablation of the close or positive margin has occurred.

    摘要翻译： 本发明提供了一种治疗方法，用于消除诸如乳房中的癌性病变，随后消融边缘。 该方法提供了在开放引导或引导成像下进行消融的定位和切除，并通过细胞学诊断。 该方法可以是在切除之前或之后具有诊断的最小侵入性同一天方法。 还提供了一种通过在监测位点处的荧光体的荧光的同时消除边缘来处理乳房中的癌性病变的切除部位的接近或正边缘的方法，以确定何时发生接近或正边缘的消融。