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1.Heterocyclic compounds useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders 有权
标题翻译: 可用于治疗肿瘤性疾病,炎症性疾病和免疫调节性疾病的杂环化合物公开(公告)号:US20080207635A1
公开(公告)日:2008-08-28
申请号:US11593191
申请日:2006-11-02
申请人: Alexey Vyacheslavovich Anikin , Vidyasagar Reddy Gantla , Vlad Edward Gregor , Luyong Jiang , Yahua Liu , Danny Peter Claude McGee , Charles Chamchoumis Mikel , Jason Conrad Pickens , Thomas Roy Webb , Zheng Yan , Tong Zhu , Aleksander Kadushkin , Sergey Sviridov , Sergey Zozulya , Alexander Chucholowski , Douglas Eric McGrath
发明人: Alexey Vyacheslavovich Anikin , Vidyasagar Reddy Gantla , Vlad Edward Gregor , Luyong Jiang , Yahua Liu , Danny Peter Claude McGee , Charles Chamchoumis Mikel , Jason Conrad Pickens , Thomas Roy Webb , Zheng Yan , Tong Zhu , Aleksander Kadushkin , Sergey Sviridov , Sergey Zozulya , Alexander Chucholowski , Douglas Eric McGrath
IPC分类号: A61K31/497 , C07D401/14 , C12N9/12 , A61K31/4439 , A61K31/4545 , A61K31/4709 , A61P35/00 , A61P3/10 , A61P9/10
CPC分类号: C07D401/04 , C07D235/18 , C07D235/20 , C07D401/10 , C07D401/14 , C07D403/04 , C07D403/14 , C07D471/10 , C07D487/04 , C07D487/10 , C07D491/04 , C07D495/04
摘要: The present invention provides compounds capable of modulating tyrosine kinases, compositions comprising the compounds and methods of their use.
摘要翻译: 本发明提供了能够调节酪氨酸激酶的化合物,包含该化合物的组合物及其使用方法。
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2.Heterocyclic compounds useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders 有权
标题翻译: 可用于治疗肿瘤性疾病,炎症性疾病和免疫调节性疾病的杂环化合物公开(公告)号:US08629147B2
公开(公告)日:2014-01-14
申请号:US11593191
申请日:2006-11-02
申请人: Alexey Vyacheslavovich Anikin , Vidyasagar Reddy Gantla , Vlad Edward Gregor , Luyong Jiang , Yahua Liu , Danny Peter Claude McGee , Charles Chamchoumis Mikel , Jason Conrad Pickens , Thomas Roy Webb , Zheng Yan , Tong Zhu , Aleksander Kadushkin , Sergey Sviridov , Sergey Zozulya , Alexander Chucholowski , Douglas Eric McGrath
发明人: Alexey Vyacheslavovich Anikin , Vidyasagar Reddy Gantla , Vlad Edward Gregor , Luyong Jiang , Yahua Liu , Danny Peter Claude McGee , Charles Chamchoumis Mikel , Jason Conrad Pickens , Thomas Roy Webb , Zheng Yan , Tong Zhu , Aleksander Kadushkin , Sergey Sviridov , Sergey Zozulya , Alexander Chucholowski , Douglas Eric McGrath
IPC分类号: A61K31/497 , A61K31/47 , A61K31/445
CPC分类号: C07D401/04 , C07D235/18 , C07D235/20 , C07D401/10 , C07D401/14 , C07D403/04 , C07D403/14 , C07D471/10 , C07D487/04 , C07D487/10 , C07D491/04 , C07D495/04
摘要: The present invention provides compounds capable of modulating tyrosine kinases, compositions comprising the compounds and methods of their use.
摘要翻译: 本发明提供了能够调节酪氨酸激酶的化合物,包含该化合物的组合物及其使用方法。
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3.Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders 有权
标题翻译: 可用于治疗肿瘤性疾病,炎症性疾病和免疫调节性疾病的三环类化合物衍生物公开(公告)号:US08063225B2
公开(公告)日:2011-11-22
申请号:US11891604
申请日:2007-08-10
申请人: Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
发明人: Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
IPC分类号: C07D401/00 , A61K31/44
CPC分类号: C07D487/04
摘要: Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
摘要翻译: 提供式(I)化合物或其调节酪氨酸激酶活性的立体异构体,互变异构体,盐,水合物或前药,包含该化合物的组合物及其使用方法。
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4.Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders 有权
标题翻译: 可用于治疗肿瘤性疾病,炎症性疾病和免疫调节性疾病的三环类化合物衍生物公开(公告)号:US20080171769A1
公开(公告)日:2008-07-17
申请号:US11891604
申请日:2007-08-10
申请人: Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
发明人: Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
IPC分类号: A61K31/444 , C07D401/14 , C12N9/99 , A61P3/10 , A61P9/10 , A61P35/00 , A61K31/4439
CPC分类号: C07D487/04
摘要: Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
摘要翻译: 提供式(I)化合物或其调节酪氨酸激酶活性的立体异构体,互变异构体,盐,水合物或前药,包含化合物的组合物及其使用方法。
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