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公开(公告)号：US06489371B2
公开(公告)日：2002-12-03
申请号：US09939312
申请日：2001-08-24
IPC分类号： C07C2700
CPC分类号： C10G2/331 , B01J23/8896 , B01J27/12 , B01J27/125 , B01J27/128 , B01J37/0201 , C07C1/0435 , C07C1/044 , C07C1/0445 , C07C2521/02 , C07C2521/04 , C07C2523/34 , C07C2523/36 , C07C2523/46 , C07C2523/745 , C07C2523/75 , C07C2523/755 , C07C2523/889 , C07C2527/12 , C07C2527/125 , C07C2527/14 , C10G2/332
摘要： A process is disclosed for producing hydrocarbons. The process involves contacting a feed stream comprising hydrogen and carbon monoxide with a catalyst in a reaction zone maintained at conversion-promoting conditions effective to produce an effluent stream comprising hydrocarbons. In accordance with this invention, the catalyst used in the process preferably includes at least cobalt, rhenium, and a promoter selected from the group including boron, phosphorus, potassium, manganese, and vanadium. The catalyst may also comprise a support material selected from the group including silica, titania, titania/alumina, zirconia, alumina, aluminum fluoride, and fluorided aluminas.
摘要翻译： 公开了一种用于生产烃的方法。 该方法包括将包含氢气和一氧化碳的进料流与催化剂接触，所述反应区域保持在有效产生包含烃的流出物流的转化促进条件下。 根据本发明，该方法中使用的催化剂优选至少包含钴，铼和选自硼，磷，钾，锰和钒的助催化剂。 催化剂还可以包含选自包括二氧化硅，二氧化钛，二氧化钛/氧化铝，氧化锆，氧化铝，氟化铝和氟化氧化铝的载体材料。
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公开(公告)号：US06333294B1
公开(公告)日：2001-12-25
申请号：US09314811
申请日：1999-05-19
IPC分类号： B01J2300
CPC分类号： C10G2/331 , B01J23/8896 , B01J27/12 , B01J27/125 , B01J27/128 , B01J37/0201 , C07C1/0435 , C07C1/044 , C07C1/0445 , C07C2521/02 , C07C2521/04 , C07C2523/34 , C07C2523/36 , C07C2523/46 , C07C2523/745 , C07C2523/75 , C07C2523/755 , C07C2523/889 , C07C2527/12 , C07C2527/125 , C07C2527/14 , C10G2/332
摘要： A process is disclosed for producing hydrocarbons. The process involves contacting a feed stream comprising hydrogen and carbon monoxide with a catalyst in a reaction zone maintained at conversion-promoting conditions effective to produce an effluent stream comprising hydrocarbons. In accordance with this invention, the catalyst used in the process includes at least cobalt, rhenium, and a promoter selected from the group including boron, phosphorus, potassium, manganese, and vanadium. The catalyst may also comprise a support material selected from the group including silica, titania, titania/alumina, zirconia, alumina, aluminum fluoride, and fluorided aluminas.
摘要翻译： 公开了一种用于生产烃的方法。 该方法包括将包含氢气和一氧化碳的进料流与催化剂接触，所述反应区域保持在有效产生包含烃的流出物流的转化促进条件下。 根据本发明，用于该方法的催化剂至少包括钴，铼和选自硼，磷，钾，锰和钒的助催化剂。 催化剂还可以包含选自包括二氧化硅，二氧化钛，二氧化钛/氧化铝，氧化锆，氧化铝，氟化铝和氟化氧化铝的载体材料。
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公开(公告)号：US08765754B2
公开(公告)日：2014-07-01
申请号：US13266921
申请日：2010-04-28
IPC分类号： A01N43/64 , A61K31/53 , C07D487/00
CPC分类号： A61K31/53 , C07D487/04 , A61K2300/00
摘要： A compound of formula (I): wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has a Btk inhibitory activity, and is useful as a method for preventing and/or treating a rheumatoid arthritis, an autoimmune disease, a B cell lymphoma of cancer, and the like.
摘要翻译： 式（I）的化合物：其中所有符号具有与说明书中定义的相同的含义; 其盐，其溶剂合物，N-氧化物或其前药具有Btk抑制活性，并且可用作预防和/或治疗类风湿性关节炎，自身免疫疾病，B细胞淋巴瘤的B细胞淋巴瘤 癌症等。
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公开(公告)号：US20120232054A1
公开(公告)日：2012-09-13
申请号：US13266921
申请日：2010-04-28
申请人： Kevin J. Moriarty , Dora Do-York Wong , Zenon Konteatis , Kristofer Moffett , Younghee Lee , Wenchun Chao
发明人： Kevin J. Moriarty , Dora Do-York Wong , Zenon Konteatis , Kristofer Moffett , Younghee Lee , Wenchun Chao
IPC分类号： A61K31/53 , A61P37/06 , A61K31/5377 , A61P7/02 , A61P35/00 , C07D487/04 , A61P37/08 , A61P29/00
CPC分类号： A61K31/53 , C07D487/04 , A61K2300/00
摘要： A compound of formula (I): wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has a Btk inhibitory activity, and is useful as a method for preventing and/or treating a rheumatoid arthritis, an autoimmune disease, a B cell lymphoma of cancer, and the like.
摘要翻译： 式（I）的化合物：其中所有符号具有与说明书中定义的相同的含义; 其盐，其溶剂合物，N-氧化物或其前药具有Btk抑制活性，并且可用作预防和/或治疗类风湿性关节炎，自身免疫疾病，B细胞淋巴瘤的B细胞淋巴瘤 癌症等。
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公开(公告)号：US06759439B2
公开(公告)日：2004-07-06
申请号：US10308494
申请日：2002-12-03
IPC分类号： C07C2700
CPC分类号： C10G2/331 , B01J23/8896 , B01J27/12 , B01J27/125 , B01J27/128 , B01J37/0201 , C07C1/0435 , C07C1/044 , C07C1/0445 , C07C2521/02 , C07C2521/04 , C07C2523/34 , C07C2523/36 , C07C2523/46 , C07C2523/745 , C07C2523/75 , C07C2523/755 , C07C2523/889 , C07C2527/12 , C07C2527/125 , C07C2527/14 , C10G2/332
摘要： A process is disclosed for producing hydrocarbons. The process involves contacting a feed stream comprising hydrogen and carbon monoxide with a catalyst in a reaction zone maintained at conversion-promoting conditions effective to produce an effluent stream comprising hydrocarbons. In accordance with this invention, the catalyst used in the process preferably includes at least cobalt, rhenium, and a promoter selected from the group including boron, phosphorus, potassium, manganese, and vanadium. The catalyst may also comprise a support material selected from the group including silica, titania, titania/alumina, zirconia, alumina, aluminum fluoride, and fluorided aluminas.
摘要翻译： 公开了一种用于生产烃的方法。 该方法包括将包含氢气和一氧化碳的进料流与催化剂接触，所述反应区域保持在有效产生包含烃的流出物流的转化促进条件下。 根据本发明，该方法中使用的催化剂优选至少包含钴，铼和选自硼，磷，钾，锰和钒的助催化剂。 催化剂还可以包含选自包括二氧化硅，二氧化钛，二氧化钛/氧化铝，氧化锆，氧化铝，氟化铝和氟化氧化铝的载体材料。
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公开(公告)号：US06727289B2
公开(公告)日：2004-04-27
申请号：US10047231
申请日：2002-01-14
申请人： Olga Ionkina , Wenchun Chao , Munirpallam A. Subramanian , Leo E. Manzer , Kamel M. Makar , Ajoy P. Raje
发明人： Olga Ionkina , Wenchun Chao , Munirpallam A. Subramanian , Leo E. Manzer , Kamel M. Makar , Ajoy P. Raje
IPC分类号： C07C2700
摘要： A process is disclosed for producing hydrocarbons. The process involves contacting a feed stream comprising hydrogen and carbon monoxide with a catalyst in a reaction zone maintained at conversion-promoting conditions effective to produce an effluent stream comprising hydrocarbons. In accordance with this invention, the catalyst used in the process includes at least a Fischer-Tropsch metal and boron. The Fischer-Tropsch metal preferably includes cobalt and optionally ruthenium or platinum. The catalyst may also comprise a support material selected from the group including silica, titania, titania/alumina, zirconia, alumina, aluminum fluoride, and fluorided aluminas.
摘要翻译： 公开了一种用于生产烃的方法。 该方法包括将包含氢气和一氧化碳的进料流与催化剂接触，所述反应区域保持在有效产生包含烃的流出物流的转化促进条件下。 根据本发明，用于该方法的催化剂至少包括费 - 托金属和硼。 费 - 托金属优选包括钴和任选的钌或铂。 催化剂还可以包含选自包括二氧化硅，二氧化钛，二氧化钛/氧化铝，氧化锆，氧化铝，氟化铝和氟化氧化铝的载体材料。
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