摘要:
A condiment distribution device. The condiment distribution device includes a tube having an open upper end and an open lower end defining a channel therebetween. A plurality of apertures are disposed on the tube. The device further includes a funnel comprising an open upper end and a connector having an open lower end, wherein the connector is removably securable to the open upper end of the elongated tube. The tube can be inserted into a container of food and a condiment poured into the open upper end of the funnel, such that it flows out of the apertures and open lower end of the tube onto the food. The condiment distribution device is configured to evenly distribute a condiment throughout a container of food.
摘要:
The present invention provides 5T4 tumour-associated antigen (TAA) for use in a method of immunotherapy of tumours. The invention also relates to a recombinant poxvirus vector from which at least one immune evasion gene has been deleted, which comprises a nucleic acid sequence encoding a 5T4 TAA and the use thereof in vaccinating against and in treating tumours.
摘要:
The invention provides the use of an enzyme and a prodrug in the manufacture of a medicament for use in inducing an anti-tumour immune response in a human patient.
摘要:
Canine and feline 5T4 polypeptide sequences and nucleotide sequences encoding them are provided. A vector system comprising a nucleic acid encoding 5T4 and a 5T4-specific agent are also provided.
摘要:
The present invention provides a vector system comprising a nucleotide sequence coding for an antibody. In particular, the present invention relates to the use of such a vector system in a subject, where the nucleotide sequence is expressed in vivo to produce said antibody.
摘要:
An apparatus for providing stabilization during a tracking operation may include a processing element configured to define an inertial pointing vector relative to a point of interest, receive tracking information related to the point of interest, and determine compensation of the inertial pointing vector based on the received tracking information and motion of a platform conducting the tracking operation.
摘要:
The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and L2, are defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
摘要:
A compound having formula (I) wherein R1, R2, R3, R4, R5 and R6 are defined in the description, is disclosed as an P2X7 antagonist. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
摘要:
The present invention provides 5T4 tumour-associated antigen (TAA) for use in a method of immunotherapy of tumours. The invention also relates to a recombinant poxvirus vector from which at least one immune evasion gene has been deleted, which comprises a nucleic acid sequence encoding a 5T4 TAA and the use thereof in vaccinating against and in treating tumours.
摘要:
A process to produce N-vinylformamide includes the steps of: reacting hydroxyethyl formamide with a reactant comprising at least one cyclic anhydride group to form an ester, and dissociating the ester via heat in a thin film evaporation to synthesize N-vinylformamide and a compound comprising at least one diacid group, the N-vinylformamide separating from the diacid during the thin film evaporation. The reactant including at least one cyclic anhydride group can, for example, be succinic anhydride, maleic anhydride, phthalic anhydride, (2-docecen-1-yl)succinic anhydride, exo-3,6-epoxy-1,2,3,6 -tetrahydrophthalic anhydride or a polymer including at least one cyclic anhydride group. A process to produce N-vinylformamide comprises the steps of: mixing acetaldehyde, formamide and a source of anhydride in a single reaction vessel, reacting the acetaldehyde, formamide and the source of anhydride in the reaction vessel under pressure, dissociating an ester formed by a reaction between the source of anhydride and hydroxyethyl formamide formed in the reaction vessel to synthesize N-vinylformamide and a compound comprising at least one diacid group.