Apparatus for delivering ions from a grounded electrospray assembly to a vacuum chamber
    1.
    发明授权
    Apparatus for delivering ions from a grounded electrospray assembly to a vacuum chamber 有权
    用于将离子从接地电喷雾组件输送到真空室的装置

    公开(公告)号:US07259368B2

    公开(公告)日:2007-08-21

    申请号:US11361125

    申请日:2006-02-24

    IPC分类号: B01D59/44 H01J49/00

    CPC分类号: H01J49/165 H01J49/045

    摘要: The present invention relates to an apparatus for delivering ions to a vacuum chamber. The apparatus comprises an ionization chamber, an ionization region within the ionization chamber, a vacuum interface at a vacuum interface voltage and a vacuum chamber, wherein the ionization chamber communicates with the vacuum chamber through the vacuum interface. Sample is introduced into the ionization chamber from an electrospray assembly at approximately ground potential. Two electrodes are provided within the chamber such that three electric fields are generated, a first field extending from the electrospray assembly to the first electrode, a second field extending from the second electrode to the first electrode, and a third field extending from the second electrode to the vacuum interface. Ions are forced to travel through the fields in order before entering the vacuum chamber. In addition, the invention provides a method of delivering ions to a vacuum chamber.

    摘要翻译: 本发明涉及一种用于将离子输送到真空室的装置。 该装置包括电离室,电离室内的电离区域,真空界面电压下的真空界面和真空室,其中电离室通过真空界面与真空室连通。 将样品从大约接地电位的电喷雾组件引入电离室。 在室内提供两个电极,使得产生三个电场,从电喷雾组件延伸到第一电极的第一场,从第二电极延伸到第一电极的第二场和从第二电极延伸的第三场 到真空界面。 在进入真空室之前,离子被迫穿过田野。 此外,本发明提供了将离子输送到真空室的方法。

    Apparatus for delivering ions from a grounded electrospray assembly to a vacuum chamber

    公开(公告)号:US06998605B1

    公开(公告)日:2006-02-14

    申请号:US09579276

    申请日:2000-05-25

    IPC分类号: B01D59/44 H01J49/00

    CPC分类号: H01J49/165 H01J49/045

    摘要: The present invention relates to an apparatus for delivering ions to a vacuum chamber. The apparatus comprises an ionization chamber, an ionization region within the ionization chamber, a vacuum interface at a vacuum interface voltage and a vacuum chamber, wherein the ionization chamber communicates with the vacuum chamber through the vacuum interface. Sample is introduced into the ionization chamber from an electrospray assembly at approximately ground potential. Two electrodes are provided within the chamber such that three electric fields are generated, a first field extending from the electrospray assembly to the first electrode, a second field extending from the second electrode to the first electrode, and a third field extending from the second electrode to the vacuum interface. Ions are forced to travel through the fields in order before entering the vacuum chamber. In addition, the invention provides a method of delivering ions to a vacuum chamber.

    Multi-mode signal offset in time-of-flight mass spectrometry
    3.
    发明授权
    Multi-mode signal offset in time-of-flight mass spectrometry 有权
    飞行时间质谱中的多模信号偏移

    公开(公告)号:US06794643B2

    公开(公告)日:2004-09-21

    申请号:US10349777

    申请日:2003-01-23

    IPC分类号: H01J4940

    CPC分类号: H01J49/0036

    摘要: A system and method of processing signals generated at a detector of a mass spectrometer prior to signal conversion in which a pre-ADC offset is applied to the signals that is adjustable in polarity and magnitude in accordance with a user-selected mode. According to a first mode, a positive offset is applied to the signals to improve quantitation accuracy and in a second mode, a negative offset is applied to the signals to improve resolution and mass assignment.

    摘要翻译: 在信号转换之前处理在质谱仪的检测器处产生的信号的系统和方法,其中根据用户选择的模式将前ADC偏移施加到可在极性和幅度上调节的信号。 根据第一模式,对信号施加正偏移以提高定量精度,并且在第二模式中,向信号施加负偏移以改善分辨率和质量分配。

    Apparatus for delivering ions from a grounded electrospray assembly to a vacuum chamber

    公开(公告)号:US07041966B2

    公开(公告)日:2006-05-09

    申请号:US10977179

    申请日:2004-10-29

    IPC分类号: B01D59/44 H01J49/00

    CPC分类号: H01J49/165 H01J49/045

    摘要: The present invention relates to an apparatus for delivering ions to a vacuum chamber. The apparatus comprises an ionization chamber, an ionization region within the ionization chamber, a vacuum interface at a vacuum interface voltage and a vacuum chamber, wherein the ionization chamber communicates with the vacuum chamber through the vacuum interface. Sample is introduced into the ionization chamber from an electrospray assembly at approximately ground potential. Two electrodes are provided within the chamber such that three electric fields are generated, a first field extending from the electrospray assembly to the first electrode, a second field extending from the second electrode to the first electrode, and a third field extending from the second electrode to the vacuum interface. Ions are forced to travel through the fields in order before entering the vacuum chamber. In addition, the invention provides a method of delivering ions to a vacuum chamber.