公开(公告)号：US09581604B2

公开(公告)日：2017-02-28

申请号：US13880475

申请日：2011-06-23

Applicant: Yoshiaki Sato ,  Ken Aoshima ,  Francois Bernier

Inventor： Yoshiaki Sato ,  Ken Aoshima ,  Francois Bernier

IPC: G01N33/92 ,  G01N33/68

CPC classification number: G01N33/6896 ,  G01N33/92 ,  Y10T436/203332

Abstract: Desmosterol alone, the combination of desmosterol and amyloid beta, the combination of desmosterol and gelsolin and the combination of desmosterol, amyloid beta and gelsolin can be used as in-blood biomarkers for Alzheimer's disease or mild cognitive impairment. A method for evaluating the effect of a candidate for a therapeutic agent to treat Alzheimer's disease or mild cognitive impairment, a method for aiding the diagnosis of Alzheimer's disease or mild cognitive impairment, and a method for diagnosing Alzheimer's disease or mild cognitive impairment are provided in which the biomarkers are used.

Abstract translation: 去头孢曲松单独使用，去头痛醇和淀粉样蛋白β的组合，去极化醇和凝溶胶蛋白的组合以及去极化醇，淀粉样蛋白β和凝溶胶蛋白的组合可用作阿尔茨海默氏病或​​轻度认知障碍的血液内生物标志物。 评估治疗剂候选者治疗阿尔茨海默氏病或​​轻度认知障碍的效果的方法，辅助诊断阿尔茨海默病或轻度认知障碍的方法以及诊断阿尔茨海默病或轻度认知障碍的方法 使用生物标志物。

公开(公告)号：US20130266589A1

公开(公告)日：2013-10-10

申请号：US13880475

申请日：2011-06-23

Applicant: Yoshiaki Sato ,  Ken Aoshima ,  Francois Bernier

Inventor： Yoshiaki Sato ,  Ken Aoshima ,  Francois Bernier

IPC: G01N33/92 ,  G01N33/68

CPC classification number: G01N33/6896 ,  G01N33/92 ,  Y10T436/203332

Abstract: Desmosterol alone, the combination of desmosterol and amyloid beta, the combination of desmosterol and gelsolin and the combination of desmosterol, amyloid beta and gelsolin can be used as in-blood biomarkers for Alzheimer's disease or mild cognitive impairment. A method for evaluating the effect of a candidate for a therapeutic agent to treat Alzheimer's disease or mild cognitive impairment, a method for aiding the diagnosis of Alzheimer's disease or mild cognitive impairment, and a method for diagnosing Alzheimer's disease or mild cognitive impairment are provided in which the biomarkers are used.

Abstract translation: 去头孢曲松单独使用，去头痛醇和淀粉样蛋白β的组合，去极化醇和凝溶胶蛋白的组合以及去极化醇，淀粉样蛋白β和凝溶胶蛋白的组合可用作阿尔茨海默氏病或​​轻度认知障碍的血液内生物标志物。 评估治疗剂候选者治疗阿尔茨海默氏病或​​轻度认知障碍的效果的方法，辅助诊断阿尔茨海默病或轻度认知障碍的方法以及诊断阿尔茨海默病或轻度认知障碍的方法 使用生物标志物。

公开(公告)号：USD688781S1

公开(公告)日：2013-08-27

申请号：US29417051

申请日：2012-03-29

Applicant: John Zenon Galasgas Vallinan ,  Siarhei V. Savich ,  Qin Fei Chen ,  Chee Ming Ng ,  Kam Poi Chia ,  Francisco J. Rodriguez ,  Lee A. Fain ,  Matthew J. Storey ,  Yoshiaki Sato

Designer： John Zenon Galasgas Vallinan ,  Siarhei V. Savich ,  Qin Fei Chen ,  Chee Ming Ng ,  Kam Poi Chia ,  Francisco J. Rodriguez ,  Lee A. Fain ,  Matthew J. Storey ,  Yoshiaki Sato

公开(公告)号：US20130046416A1

公开(公告)日：2013-02-21

申请号：US13579056

申请日：2010-12-20

Applicant: Kazuyoshi Osako ,  Yoshiaki Sato

Inventor： Kazuyoshi Osako ,  Yoshiaki Sato

IPC: G05F5/00

CPC classification number: G05F1/67 ,  H02J3/385 ,  Y02E10/58

Abstract: Disclosed is a solar photovoltaic power generator system that includes a solar cell panel and a power conditioner that controls a voltage or a current of generated power output from the solar cell panel as an operating value in accordance with a characteristic of the solar cell panel to search a maximum output point of the generated power so as to be supplied to a power system. The power conditioner includes a data memory module that stores a plurality of operating values and a plurality of patterns of the generated powers from the solar cell panel based on the operating values, and a maximum power point tracking module that adds a new operating value based on the pattern of the generated power in the past to calculate the operating values for the next search, and sets the maximum value through an algorithm.

Abstract translation: 公开了一种太阳能光伏发电系统，其包括：太阳能电池面板和功率调节器，其根据太阳能电池面板的特性来控制从太阳能电池面板输出的发电功率的电压或电流作为工作值进行搜索 产生的电力的最大输出点，以供应给电力系统。 功率调节器包括数据存储器模块，其基于操作值存储来自太阳能电池面板的多个操作值和多个图案的生成的功率;以及最大功率点跟踪模块，其基于 过去产生的功率的模式来计算下一次搜索的操作值，并通过算法设置最大值。

公开(公告)号：US07942812B2

公开(公告)日：2011-05-17

申请号：US11674772

申请日：2007-02-14

Applicant: Yoshiaki Sato

Inventor： Yoshiaki Sato

IPC: A61B1/00

CPC classification number: A61B1/042 ,  A61B6/10

Abstract: A diagnosis system composed of a fluoroscopic apparatus for obtaining a fluoroscopic image of an internal body be radiating x-rays to the body, and an endocopic apparatus for obtaining an optical image of the internal body part to be observed by inserting an insertion section of the endoscope into the body. In an operating section of the endoscope, a fluoroscope operating section for operating the fluoroscopic apparatus is disposed. Operation signals from the fluoroscope operating section are sent from a communication I/F of an endoscopic processor to the fluoroscopic apparatus. The fluoroscoptic apparatus receives the operation signals with a fluoroscopic processor and controls a fluoroscopic table.

Abstract translation: 由用于获得内部主体的透视图像的荧光检查装置构成的诊断系统将X射线照射到身体，以及内窥镜装置，用于通过插入所述内窥镜的插入部分来获得待观察的内部身体部分的光学图像 内窥镜进入体内。 在内窥镜的操作部中设置有用于操作荧光检查装置的荧光镜操作部。 来自荧光镜操作部的操作信号从内窥镜处理器的通信I / F发送到荧光检查装置。 荧光装置用荧光检查处理器接收操作信号并控制透视表。

公开(公告)号：US07855467B2

公开(公告)日：2010-12-21

申请号：US12015609

申请日：2008-01-17

Applicant: Hironari Kawazoe ,  Motoo Futami ,  Youji Ikeda ,  Yoshiaki Sato

Inventor： Hironari Kawazoe ,  Motoo Futami ,  Youji Ikeda ,  Yoshiaki Sato

IPC: F03D9/02

CPC classification number: F03D7/028 ,  F03D7/042 ,  F03D9/11 ,  F03D9/25 ,  F05B2270/301 ,  H02J3/32 ,  H02J3/383 ,  H02J3/386 ,  Y02E10/563 ,  Y02E10/566 ,  Y02E10/723 ,  Y02E10/725 ,  Y02E10/763 ,  Y02E10/766 ,  Y02E40/10 ,  Y02E70/30 ,  Y10T307/527

Abstract: A hybrid system using a wind-power generator and a battery energy storage system includes a unit to set a system constant output value, a unit to control power generated from the wind-power generator, a unit to gradually change an output target value between an output constant operation and a regulation control operation, and a control unit to secure a charged ampere-hour of a battery in the output constant operation.

Abstract translation: 使用风力发电机和电池能量存储系统的混合动力系统包括用于设定系统恒定输出值的单元，用于控制从风力发电机产生的电力的单元，用于逐渐改变输出目标值之间的单位 输出恒定操作和调节控制操作，以及控制单元，用于在输出恒定操作中确保电池的充电安培小时。

公开(公告)号：US20100279820A1

公开(公告)日：2010-11-04

申请号：US12522437

申请日：2007-12-26

Applicant: Yoshiaki Sato

Inventor： Yoshiaki Sato

IPC: A63B24/00

CPC classification number: A63B21/008 ,  A63B21/00069 ,  A63B21/00076 ,  A63B21/00196 ,  A63B21/0023 ,  A63B21/0552 ,  A63B21/0555 ,  A63B21/0557 ,  A63B21/4025 ,  A63B24/00 ,  A63B2209/10 ,  A63B2220/56 ,  A63B2225/62 ,  A63B2230/04 ,  A63B2230/06 ,  A63B2230/062 ,  A63B2230/207

Abstract: A training system includes a tight fitting device 100 having an inflatable tube which is intended to be wrapped around a compression target range of an arm or a leg, a pressure regulating segment 200 that controls an applied pressure applied by the tight fitting device 100 to the compression target range by means of supplying air into the inflatable tube of the tight fitting device 100 or removing the air from the inflatable tube, a measuring segment 300, and a control segment 400. The measuring segment 300 measures a measurement target value which is one of a heart beat rate, a pulse wave value, and an oxygen saturation value, of a user who is receiving KAATSU training. When the measurement target value measured by the measuring segment 300 indicates that the KAATSU training should not be continued, then the control segment 400 notifies it to the pressure regulating segment 200 and terminates the KAATSU training.

Abstract translation: 训练系统包括紧固装置100，其具有旨在围绕臂或腿的压缩目标范围的可充气管;压力调节段200，其将紧密装置100施加的施加压力控制到 压缩目标范围，通过将空气供应到紧密装置100的可充气管中或从可充气管，测量段300和控制段400中移除空气。测量段300测量一个测量目标值 的心率，脉搏波值和氧饱和度值，用于接受KAATSU训练。 当由测量段300测量的测量目标值指示不应该继续KAATSU训练时，控制段400将其通知给压力调节段200并终止KAATSU训练。

公开(公告)号：US07824334B2

公开(公告)日：2010-11-02

申请号：US11312466

申请日：2005-12-21

Applicant: Yoshiaki Sato

Inventor： Yoshiaki Sato

IPC: A61B8/00

CPC classification number: G06T5/004 ,  G06T2207/10132 ,  G06T2207/30004

Abstract: An ultrasonograph is provided with a frequency component adjuster that adjusts spatial frequency components of original image data RAW0 of an ultrasonotomographic image. The frequency component adjuster is constituted of an unsharp image data generator, a subtraction circuit, a weighting circuit, an integration circuit, a multiplication circuit and an addition circuit. The unsharp image data generator circuit generates unsharp image data RAWi (i=1 to 5) by reducing the spatial frequency components of the original image data RAW0 in five steps. The subtraction circuit generates differential image data ΔRAWj (j=1 to 4) by subtracting the unsharp image data RAW1 from RAWi-1. The weighting circuit weights the differential image data ΔRAWj by multiplying them by respective coefficients kj (−1

Abstract translation: 超声波诊断仪设置有调整超声波图像的原始图像数据RAW0的空间频率分量的频率分量调整器。 频率分量调整器由清晰图像数据发生器，减法电路，加权电路，积分电路，乘法电路和加法电路构成。 不清晰的图像数据生成器电路通过以五个步骤减少原始图像数据RAW0的空间频率分量来生成不清晰的图像数据RAWi（i = 1至5）。 减法电路通过从RAWi-1中减去不清晰图像数据RAW1来生成差分图像数据＆Dgr; RAWj（j = 1至4）。 加权电路通过将它们乘以相应的系数kj（-1

公开(公告)号：US07767812B2

公开(公告)日：2010-08-03

申请号：US12346544

申请日：2008-12-30

Applicant: Hitoshi Harada ,  Hiroshi Ishihara ,  Yoshiaki Sato ,  Hiroyuki Chiba ,  Yuki Komatsu ,  Susumu Inoue ,  Naoki Ozeki

Inventor： Hitoshi Harada ,  Hiroshi Ishihara ,  Yoshiaki Sato ,  Hiroyuki Chiba ,  Yuki Komatsu ,  Susumu Inoue ,  Naoki Ozeki

IPC: C07D401/00 ,  C07D403/00 ,  C07D405/00 ,  C07D409/00 ,  C07D411/00 ,  C07D413/00 ,  C07D417/00 ,  C07D419/00

CPC classification number: C07D405/14 ,  C07D405/06

Abstract: Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one having a diffraction peak at a diffraction angle (2θ±0.2°) of 9.7° and/or 21.9° in a powder X-ray diffraction are suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation. Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate and amorphous 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate are also suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation.

Abstract translation: 在衍射角（2θ;±0.2°）为9.7°的衍射峰的5- [2-氨基-4-（2-呋喃基）嘧啶-5-基] -1-甲基吡啶-2（1H） - 酮的晶体 °和/或21.9°在粉末X射线衍射中适用于诸如便秘的疾病的预防和治疗剂的活性成分。 5- [2-氨基-4-（2-呋喃基）嘧啶-5-基] -1-甲基吡啶-2（1H） - 酮水合物和无定形的5- [2-氨基-4-（2-呋喃基） 嘧啶-5-基] -1-甲基吡啶-2（1H） - 酮水合物也适用于诸如便秘等疾病的预防和治疗剂的活性成分。

公开(公告)号：US07749428B2

公开(公告)日：2010-07-06

申请号：US11727440

申请日：2007-03-27

Applicant: Hiroyuki Sugawara ,  Yasuo Ido ,  Yoshiaki Sato ,  Yukio Ogita ,  Shigemasa Hakakoshi

Inventor： Hiroyuki Sugawara ,  Yasuo Ido ,  Yoshiaki Sato ,  Yukio Ogita ,  Shigemasa Hakakoshi

IPC: B22F7/04

CPC classification number: B22F7/08 ,  B22F3/18 ,  B22F2998/10 ,  Y10T428/12021 ,  Y10T428/12493 ,  B22F7/002 ,  B22F3/10

Abstract: A manufacturing method of a clad material composed of a bronze alloy and a steel is provided, including: scattering a bronze alloy powder on a steel back metal; sintering the bronze alloy powder to obtain a bilayer material having a porous bronze alloy layer on the steel; dry-rolling and a sintering the bilayer material so that the bronze alloy layer has a porosity of 3% or less; and wet-rolling the bilayer material with supplying a rolling oil to surfaces of rolling rolls. The clad manufactured according to this method can be heat-treated without an disadvantage in a conventional wet-rolling that entering rolling oil vaporizes in the bronze alloy layer during the heat treatment to form new voids. Therefore, it becomes possible to make a bronze alloy layer high in density in small times of rolling, thus enabling an increase in production efficiency.

Abstract translation: 提供由青铜合金和钢构成的复合材料的制造方法，包括：将青铜合金粉末分散在钢背金属上; 烧结青铜合金粉末以获得在钢上具有多孔青铜合金层的双层材料; 干轧和烧结双层材料，使得青铜合金层的孔隙率为3％以下; 并通过向轧辊的表面供给轧制油将双层材料进行湿式轧制。 根据该方法制造的包层可以在热处理期间在常规的湿式轧制中进行热处理，而不需要进入轧制油在青铜合金层中蒸发而形成新的空隙。 因此，可以在少量轧制中使青铜合金层的密度高，从而能够提高生产效率。