公开(公告)号：US20120230973A1

公开(公告)日：2012-09-13

申请号：US13395748

申请日：2010-09-16

申请人： Masataka Goto ,  Yoshihike Hirose

发明人： Masataka Goto ,  Yoshihike Hirose

IPC分类号： A61K38/47 ,  A61P1/04

CPC分类号： A61K33/00 ,  A23L29/06 ,  A23L33/10 ,  A61K31/194 ,  A61K33/10 ,  A61K33/42 ,  A61K38/00 ,  A61K38/47 ,  A61K2300/00

摘要： Disclosed is a lactase preparation which does not undergo the deactivation of lactase even when the preparation is ingested prior to the ingestion of a lactase-containing food or drink such as a milk product and therefore can decompose lactase stably and which can prevent the symptoms of lactase intolerance. Specifically disclosed is a lactase preparation comprising lactase and at least one component selected from trisodium citrate, potassium sodium tartrate, calcium carbonate, sodium carbonate and calcium hydrogen phosphate which acts as an antacid. The lactase preparation is characterized by being intended to be ingested prior to the ingestion of a lactase-containing food or drink to decompose lactase. In the lactase preparation, the antacid is contained at such a content per unit dosage form that the pH value in the stomach can be increased to 4 or higher after the ingestion of the preparation.

摘要翻译： 公开了即使在摄取含有乳糖酶的食品或饮料如乳制品之前摄取制剂也不会使乳糖酶失活的乳糖酶制剂，因此可以稳定地分解乳糖酶，并且可以防止乳糖酶的症状 不宽容 具体公开的是含有乳糖酶和选自柠檬酸三钠，酒石酸钾钠，碳酸钙，碳酸钠和磷酸氢钙中的至少一种成分作为抗酸剂的乳糖酶制剂。 乳糖酶制剂的特征在于在摄入含有乳糖酶的食品或饮料之前摄取以分解乳糖酶。 在乳糖酶制剂中，抗酸剂以每单位剂型的含量包含，使得在摄取制剂后胃中的pH值可以增加至4或更高。