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    MONOMERS, POLYMERS, AND ARTICLES FOR BIOMATERIAL CAPTURE
    1.
    发明公开
    MONOMERS, POLYMERS, AND ARTICLES FOR BIOMATERIAL CAPTURE 审中-公开

    公开(公告)号：US20230203221A1

    公开(公告)日：2023-06-29

    申请号：US17995427

    申请日：2021-04-06

    申请人： 3M INNOVATIVE PROPERTIES COMPANY

    发明人： Jerald K. Rasmussen ,  Eli P. Narveson

    IPC分类号： C08F220/36 ,  C08F220/38

    CPC分类号： C08F220/365 ,  C08F220/387

    摘要： Monomers, polymers formed from such monomers, and articles for biomaterial capture including such polymers, wherein the monomer is represented by the following general Formula (I): CH2═CR1—C(═O)—X—R2—Z—X3—NR3—C(═X2)-X1—R4, wherein: R1 is H or —CH3; R2 is a (hetero)hydrocarbylene; X is —O— or —NH—; X1 is —O—, —S—, —NH—, or a single bond; X2 is —O— or —S—; X3 is —O— or —NR5—; R4 is hydrogen, (hetero)hydrocarbyl, or —N(R3)2; each R3 and R5 is independently hydrogen or a (hetero)hydrocarbyl; and Z is —C(═O)— or —NH—C(═O)—.

    Functionalized copolymers and use thereof
    3.
    发明授权
    Functionalized copolymers and use thereof 有权

    公开(公告)号：US11446613B2

    公开(公告)日：2022-09-20

    申请号：US16328389

    申请日：2017-08-30

    申请人： 3M INNOVATIVE PROPERTIES COMPANY

    发明人： Andrew W. Vail ,  Semra Colak Atan ,  Jerald K. Rasmussen ,  George W. Griesgraber ,  Catherine A. Bothof

    IPC分类号： B01D71/00 ,  B01D69/00 ,  C07K1/34 ,  B01D71/40 ,  B01D69/02 ,  B01D69/12 ,  B01D71/78 ,  C07K16/00 ,  C09D133/26 ,  B01D67/00

    摘要： An article that includes a functionalized copolymer and the use thereof, particularly in a process for binding biomaterials, such as in a process for separating aggregated proteins from monomeric proteins in a biological solution; wherein the article includes: a) a porous substrate; and b) a copolymer covalently attached to the porous substrate, the copolymer comprising a hydrocarbon backbone and a plurality of pendant groups attached to the hydrocarbon backbone, wherein 1) each of a first plurality of pendant groups comprises: (a) at least one acidic group or salt thereof; and (b) a spacer group that directly links the at least one acidic group or salt thereof to the hydrocarbon backbone by a chain of at least 6 catenated atoms; and 2) each of a second plurality of pendant groups comprises: (a) at least one acidic group or salt thereof; and (b) a spacer group that directly links the at least one acidic group or salt thereof to the hydrocarbon backbone by a chain of at least 6 catenated atoms; and wherein the first plurality of pendant groups are different than the second plurality of pendant groups; and wherein a mole ratio of the first plurality of pendant groups to the second plurality of pendant groups is in a range of 95:5 to 5:95.

    Hydrogel compositions bonded to polymeric substrates
    4.
    发明授权
    Hydrogel compositions bonded to polymeric substrates 有权

    公开(公告)号：US11278639B2

    公开(公告)日：2022-03-22

    申请号：US16485580

    申请日：2018-03-23

    申请人： 3M INNOVATIVE PROPERTIES COMPANY

    发明人： Alexi J. Young ,  Jerald K. Rasmussen

    IPC分类号： A61L15/60 ,  C08J3/075 ,  C08J7/06 ,  C09D4/00 ,  C08J7/056

    摘要： Described herein is a hydrogel-containing multilayer article and methods of making, said hydrogel-containing multilayer article comprising: (i) a polymeric substrate comprising an abstractable atom; and (ii) a cured aqueous coating composition thereon wherein the coating composition comprises: (a) a hydrophilic monomer comprising a (meth)acrylamide, (meth)acrylate, and combinations thereof: (b) at least 2 wt % of a water-swellable clay; (c) a water-soluble type I photoinitiator; and (d) an acid or salt wherein a water insoluble type II photoinitiator is localized at the interface between the hydrogel coating and the polymeric substrate.