Abstract:
Porous polymeric resins, reaction mixtures and methods that can be used to prepare the porous polymeric resins, and uses of the porous polymeric resin are described. More specifically, the polymeric resins typically have a hierarchical porous structure plus reactive groups that can be used to interact with or react with a variety of different target compounds. The reactive groups can be selected from an acidic group or a salt thereof, an amino group or salt thereof, a hydroxyl group, an azlactone group, a glycidyl group, or a combination thereof.
Abstract:
A filtration media is disclosed comprising a hydrophobic monomer grafted onto a support, the hydrophobic monomer having the structure: CH2═CR4C(O)NHC(R1R1)(C(R1R1))nC(O)XR3 wherein n is an integer of 0 or 1; R1 is independently selected from at least one of: a hydrogen atom, alkyls, aryls, and alkylaryls, wherein the alkyls, aryls, and alkylaryls have a total of 10 carbon atoms or less; R3 is a hydrophobic group selected from at least one of: alkyls, aryls, alkylaryls and ethers, wherein the alkyls, aryls, alkylaryls and ethers have a total number of carbon atoms ranging from 4 to 30; R4 is H or CH3; X is O or NH. In some embodiments the hydrophobic monomer is derived from an amine or an alcohol (HXR3) that has a hydrophilicity index of 25 or less. Such media may be used in applications such as hydrophobic interaction chromatography.
Abstract translation:其中n为0或1的整数; R 1独立地选自氢原子,烷基,芳基和烷基芳基中的至少一个,其中烷基,芳基和烷基芳基总共具有10个或更少的碳原子; R3是选自烷基,芳基,烷基芳基和醚中的至少一种的疏水基团,其中烷基,芳基,烷基芳基和醚的总碳原子数范围为4-30; R4是H或CH3; X是O或NH。 在一些实施方案中,疏水性单体衍生自亲水性指数为25以下的胺或醇(HXR3)。 这样的介质可以用于诸如疏水相互作用层析的应用中。
Abstract:
Porous polymeric resins, reaction mixtures and methods that can be used to prepare the porous polymeric resins, and uses of the porous polymeric resin are described. More specifically, the polymeric resins typically have a hierarchical porous structure plus reactive groups that can be used to interact with or react with a variety of different target compounds. The reactive groups can be selected from an acidic group or a salt thereof, an amino group or salt thereof, a hydroxyl group, an azlactone group, a glycidyl group, or a combination thereof.