MAGNETOTACTIC BACTERIA MRI POSITIVE CONTRAST ENHANCEMENT AGENT AND METHODS OF USE
    4.
    发明申请
    MAGNETOTACTIC BACTERIA MRI POSITIVE CONTRAST ENHANCEMENT AGENT AND METHODS OF USE 审中-公开
    MAGNETOTACTIC BACTERIA MRI正向对比增强剂及其使用方法

    公开(公告)号:US20100135912A1

    公开(公告)日:2010-06-03

    申请号:US12627299

    申请日:2009-11-30

    IPC分类号: A61K49/08 C12N1/20

    摘要: Magnetic resonance imaging (MRI) is enhanced by contrast agents such as superparamagnetic iron-oxide (SPIO) particles that resemble magnetite particles produced by magnetotactic bacteria. Magnetospirillum magneticum AMB-1 produces positive MRI contrast when generating ultrasmall magnetite particles (10-40 nm diameter). Positive MRI contrast permits clearer distinction from image voids compared to negative contrast. T1-weighted MRI showed that such bacteria increased positive contrast 2.2-fold (p

    摘要翻译: 磁共振成像(MRI)通过造影剂增强,如超顺磁性氧化铁(SPIO)颗粒,类似于由磁能细菌产生的磁铁矿颗粒。 当产生超小磁铁矿颗粒(直径为10-40nm)时,Magnetospirillum magneticum AMB-1产生正的MRI对比度。 与负面对比相比,正面MRI对比可以更清晰地区分图像空洞。 T1加权MRI显示,在小鼠肿瘤异种移植物中肿瘤内注射后,这种细菌体外增加了2.2倍(p <0.02)和2.0倍(p <0.02)。 静脉输送后,Magnetospirillum磁性AMB-1靶向肿瘤并产生增加的阳性MRI对比(1.4倍; p <0.01)。 通过活细胞计数,放射性标记的AMB-1的microPET成像和肿瘤切片的普鲁士蓝染色显示AMB-1肿瘤靶向。 因此,磁性细菌提供了通过MRI改善癌症诊断和监测治疗反应的工具。

    Rotary positive displacement mechanism
    5.
    发明授权
    Rotary positive displacement mechanism 失效
    旋转正位移机构

    公开(公告)号:US4391574A

    公开(公告)日:1983-07-05

    申请号:US130191

    申请日:1980-03-13

    IPC分类号: F01C3/02

    CPC分类号: F01C3/02

    摘要: A device having a power rotor and a seal rotor which have coincident center points. The power rotor rotates in a plane which is perpendicular to that within which the seal rotor rotates. The power rotor has a rotor body to which are attached a plurality of outwardly extending vanes. The seal rotor has a rim gear to which are attached a plurality of inwardly extending vanes. The power rotor vanes and the seal rotor vanes interdigitate upon rotation of the rotors to define two variable volume chambers. The power rotor vanes and the seal rotor vanes are designed and constructed to insure a close mesh during such interdigitation and means are provided for adjusting the position of the power rotor vanes relative to the seal rotor vanes to insure proper interdigitation.

    摘要翻译: 具有动力转子和密封转子的装置具有重合的中心点。 动力转子在垂直于密封转子旋转的平面内旋转。 动力转子具有转子体,多个向外延伸的叶片附接到转子体上。 密封转子具有轮辋齿轮,多个向内延伸的叶片连接到轮辋齿轮上。 动力转子叶片和密封转子叶片在转子旋转时互相指向以限定两个可变容积室。 动力转子叶片和密封转子叶片被设计和构造以在这种相互交织期间确保紧密的网格,并且提供用于调节动力转子叶片相对于密封转子叶片的位置的装置,以确保适当的交叉指向。

    ACETATE-RESISTANT YEAST STRAIN FOR THE PRODUCTION OF A FERMENTATION PRODUCT
    6.
    发明申请
    ACETATE-RESISTANT YEAST STRAIN FOR THE PRODUCTION OF A FERMENTATION PRODUCT 审中-公开
    用于生产发酵产品的耐乙酸乙酯菌株

    公开(公告)号:US20130071904A1

    公开(公告)日:2013-03-21

    申请号:US13578042

    申请日:2011-05-27

    申请人: Yoram Barak

    发明人: Yoram Barak

    IPC分类号: C12P7/10

    摘要: The present invention provides methods and compositions for fermentations comprising acetate-resistant yeast. The present invention provides methods for use of acetate-resistant yeast for the production of fermentation products.

    摘要翻译: 本发明提供了包含耐乙酸酵母的发酵方法和组合物。 本发明提供了使用耐乙酸酵母来生产发酵产物的方法。