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公开(公告)号：US11109836B2
公开(公告)日：2021-09-07
申请号：US15406083
申请日：2017-01-13
Applicant: ACIST MEDICAL SYSTEMS, INC.
Inventor： Jason F. Hiltner , Kendall R. Waters , Thomas C. Moore , Robert Zelenka
Abstract: Embodiments of the present invention allow more full characterization of a stenotic lesion by measuring both pressure drop across the stenotic lesion and the size of the vessel lumen adjacent the stenotic lesion, both with sensors delivered intravascularly to the stenotic lesion site. In preferred embodiments, the size (e.g., inner diameter, cross-sectional profile) of the vessel lumen adjacent the stenotic lesion can be measured via one or more intravascular ultrasound transducers. In preferred embodiments, the intravascular ultrasound transducer(s) can be delivered to the site of the stenotic lesion with the same delivery device that carries the pressure transducer(s).
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公开(公告)号：US10553776B2
公开(公告)日：2020-02-04
申请号：US15387905
申请日：2016-12-22
Applicant: ACIST Medical Systems, Inc.
Inventor： Richard Bautista , Robert Zelenka
Abstract: An ultrasonic transducer includes a backing element, an active element overlying the backing layer, and a matching element overlying the active element, the matching element having an inner surface that contacts the active element and an outer surface with a non-homogeneous texture and/or material composition. The matching element may be formed by subtractive or deposition techniques.
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公开(公告)号：US09610425B2
公开(公告)日：2017-04-04
申请号：US14507438
申请日：2014-10-06
Applicant: ACIST Medical Systems, Inc.
Inventor： Kendall R. Waters , Thomas C. Moore , Robert Zelenka , Paul Zalesky
CPC classification number: A61M25/0133 , A61B8/0883 , A61B8/12 , A61B8/445 , A61B8/5223 , A61M25/0084 , A61M25/0662 , A61M2025/0089 , A61M2025/0166 , A61M2025/0175 , A61M2025/0681 , A61M2210/125
Abstract: Methods of providing image-guided transendocardial injection of a therapeutic agent into a left ventricular wall of a heart. Some methods enable injections into heart tissue under visualization. The methods may include providing an endoventricular injection catheter having integrated echocardiographic capability. The endoventricular injection catheter may have an imaging core and an injection system carried on the elongated body with the imaging core. The method may include positioning the endoventricular injection catheter into the left ventricle of the heart, which inserts the imaging core into the heart. The method may also include transmitting ultrasonic energy via the imaging core, receiving reflected ultrasonic energy at the distal end, visualizing the left ventricular wall of the heart using the imaging core, identifying infarct regions of the left ventricle, and injecting a therapeutic agent into the visualized infarcted regions of the left ventricle using the injection system.
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公开(公告)号：US09530955B2
公开(公告)日：2016-12-27
申请号：US13679847
申请日：2012-11-16
Applicant: ACIST MEDICAL SYSTEMS, INC.
Inventor： Richard Bautista , Robert Zelenka
CPC classification number: H01L41/0825 , B06B1/067 , H01L41/0805 , H01L41/081 , H01L41/277 , H04R1/023 , H04R1/1016 , H04R1/1091 , H04R31/00 , Y10T29/42
Abstract: An ultrasonic transducer includes a backing element, an active element overlying the backing layer, and a matching element overlying the active element, the matching element having an inner surface that contacts the active element and an outer surface with a non-homogeneous texture and/or material composition. The matching element may be formed by subtractive or deposition techniques.
Abstract translation: 超声波换能器包括背衬元件，覆盖背衬层的有源元件和覆盖有源元件的匹配元件，匹配元件具有接触有源元件的内表面和具有不均匀纹理的外表面和/或 材料组成。 匹配元件可以由减法或沉积技术形成。
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公开(公告)号：US20170055943A1
公开(公告)日：2017-03-02
申请号：US15347939
申请日：2016-11-10
Applicant: ACIST MEDICAL SYSTEMS, INC.
Inventor： Robert Zelenka , Ruth E. Beeby
CPC classification number: A61B8/445 , A61B8/12 , B29C61/006 , B29C65/02 , B29C65/18 , B29C65/68 , B29C66/0042 , B29C66/1142 , B29C66/1282 , B29C66/12841 , B29C66/5221 , B29C66/63 , B29C66/71 , B29C66/8122 , B29C66/91421 , B29C66/919 , B29L2031/7542 , B29K2023/06 , B29K2827/18
Abstract: An imaging window of an imaging catheter includes a first imaging window section and a second imaging window section. The first imaging window section has a finite length and is formed from a first material having a flexural modulus. The second imaging window section has a finite length and is formed from a second material having a flexural modulus. The flexural modulus of the first material is different than the flexural modulus of the second material.
Abstract translation: 成像导管的成像窗口包括第一成像窗口部分和第二成像窗口部分。 第一成像窗口部分具有有限的长度并且由具有挠曲模量的第一材料形成。 第二成像窗口部分具有有限的长度并且由具有挠曲模量的第二材料形成。 第一材料的挠曲模量与第二材料的挠曲模量不同。
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6.发明申请
公开(公告)号：US20150025381A1
公开(公告)日：2015-01-22
申请号：US14507438
申请日：2014-10-06
Applicant: ACIST Medical Systems, Inc.
Inventor： Kendall R. Waters , Thomas C. Moore , Robert Zelenka , Paul Zalesky
CPC classification number: A61M25/0133 , A61B8/0883 , A61B8/12 , A61B8/445 , A61B8/5223 , A61M25/0084 , A61M25/0662 , A61M2025/0089 , A61M2025/0166 , A61M2025/0175 , A61M2025/0681 , A61M2210/125
Abstract: Methods of providing image-guided transendocardial injection of a therapeutic agent into a left ventricular wall of a heart. Some methods enable injections into heart tissue under visualization. The methods may include providing an endoventricular injection catheter having integrated echocardiographic capability. The endoventricular injection catheter may have an imaging core and an injection system carried on the elongated body with the imaging core. The method may include positioning the endoventricular injection catheter into the left ventricle of the heart, which inserts the imaging core into the heart. The method may also include transmitting ultrasonic energy via the imaging core, receiving reflected ultrasonic energy at the distal end, visualizing the left ventricular wall of the heart using the imaging core, identifying infarct regions of the left ventricle, and injecting a therapeutic agent into the visualized infarcted regions of the left ventricle using the injection system.
Abstract translation: 向心脏左心室壁提供图像引导的经心内注射治疗剂的方法。 一些方法可以在可视化下注入心脏组织。 所述方法可以包括提供具有整合的超声心动图能力的室内注射导管。 室内注射导管可以具有成像芯和注射系统，该注射系统用成像芯承载在细长体上。 该方法可以包括将室内注射导管定位到心脏的左心室，其将成像核心插入心脏。 该方法还可以包括经由成像核心传送超声波能量，在远端处接收反射的超声能量，使用成像核心可视化心脏的左心室壁，识别左心室的梗死区域，以及将治疗剂注入 使用注射系统观察左心室的梗死区域。
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公开(公告)号：US20130253328A1
公开(公告)日：2013-09-26
申请号：US13833919
申请日：2013-03-15
Applicant: ACIST MEDICAL SYSTEMS, INC.
Inventor： Robert Zelenka , Ruth E. Beeby , Kendall R. Waters
CPC classification number: A61M25/0054 , A61B8/12 , A61M25/0009 , A61M25/0012 , B29C71/0063 , B29C2071/022
Abstract: A catheter a first sheath having a proximal end and a distal end, and a length extending between the proximal end and the distal end. The first sheath being devoid of any bonds between the proximal end and the distal end, and a flexural modulus of the first sheath varying along the length. A method of making a catheter having more than one flexural modulus.
Abstract translation: 导管，具有近端和远端的第一护套，以及在近端和远端之间延伸的长度。 第一护套在近端和远端之间没有任何接合，并且第一护套的弯曲模量沿长度变化。 制造具有多于一个挠曲模量的导管的方法。
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公开(公告)号：US11147535B2
公开(公告)日：2021-10-19
申请号：US15347939
申请日：2016-11-10
Applicant: ACIST MEDICAL SYSTEMS, INC.
Inventor： Robert Zelenka , Ruth E. Beeby
IPC: A61B8/00 , A61B8/12 , A61M25/00 , B29C65/18 , B29C65/68 , B29C65/00 , B29L31/00 , B29C65/02 , A61B17/00 , B29C61/00
Abstract: An imaging window of an imaging catheter includes a first imaging window section and a second imaging window section. The first imaging window section has a finite length and is formed from a first material having a flexural modulus. The second imaging window section has a finite length and is formed from a second material having a flexural modulus. The flexural modulus of the first material is different than the flexural modulus of the second material.
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公开(公告)号：US20180000449A1
公开(公告)日：2018-01-04
申请号：US15705321
申请日：2017-09-15
Applicant: ACIST Medical Systems, Inc.
Inventor： Thomas C. Moore , Kendall R. Waters , Stephanie J. Buech , Robert Zelenka
IPC: A61B8/00 , A61B1/273 , A61B1/313 , A61B18/14 , A61B1/00 , A61B8/12 , A61B1/233 , A61B8/08 , A61B18/02 , A61B17/00 , A61B18/00
CPC classification number: A61B8/445 , A61B1/00082 , A61B1/018 , A61B1/233 , A61B1/2733 , A61B1/3137 , A61B8/0841 , A61B8/0883 , A61B8/12 , A61B8/4461 , A61B8/4466 , A61B8/4494 , A61B8/5223 , A61B8/5253 , A61B18/1492 , A61B34/25 , A61B90/37 , A61B2017/00243 , A61B2017/00557 , A61B2017/00991 , A61B2018/00577 , A61B2018/00982 , A61B2018/0212 , A61B2090/3784
Abstract: A catheter-based imaging system comprises a catheter having a telescoping proximal end, a distal end having a distal sheath and a distal lumen, a working lumen, and an ultrasonic imaging core. The ultrasonic imaging core is arranged for rotation and linear translation. The system further includes a patient interface module including a catheter interface, a rotational motion control system that imparts controlled rotation to the ultrasonic imaging core, a linear translation control system that imparts controlled linear translation to the ultrasonic imaging core, and an ultrasonic energy generator and receiver coupled to the ultrasonic imaging core. The system further comprises an image generator coupled to the ultrasonic energy receiver that generates an image.
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公开(公告)号：US20170104148A1
公开(公告)日：2017-04-13
申请号：US15387905
申请日：2016-12-22
Applicant: ACIST Medical Systems, Inc.
Inventor： Richard Bautista , Robert Zelenka
IPC: H01L41/08 , B06B1/06 , H01L41/277
CPC classification number: H01L41/0825 , B06B1/067 , H01L41/0805 , H01L41/081 , H01L41/277 , H04R1/023 , H04R1/1016 , H04R1/1091 , H04R31/00 , Y10T29/42
Abstract: An ultrasonic transducer includes a backing element, an active element overlying the backing layer, and a matching element overlying the active element, the matching element having an inner surface that contacts the active element and an outer surface with a non-homogeneous texture and/or material composition. The matching element may be formed by subtractive or deposition techniques.
