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1.发明申请公开(公告)号：US20180064579A1
公开(公告)日：2018-03-08
申请号：US15804882
申请日：2017-11-06
Applicant: AMO DEVELOPMENT, LLC
Inventor： Mark E. Arnoldussen , Jonathan Wong , Benjamin A. Logan , Leander Zickler
IPC: A61F9/008
CPC classification number: A61F9/00814 , A61B2017/00057 , A61B2017/00154 , A61F9/008 , A61F9/00802 , A61F9/00817 , A61F2009/00844 , A61F2009/00846 , A61F2009/00848 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , A61F2009/00885 , A61F2009/00897
Abstract: Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such penetration of the epithelial layer can be detected.
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公开(公告)号：US09662006B2
公开(公告)日：2017-05-30
申请号：US15175179
申请日：2016-06-07
Applicant: AMO Development, LLC
Inventor： Guang-ming Dai , Leander Zickler
CPC classification number: A61B3/0025 , A61B3/1015 , A61B3/107 , A61B3/112 , A61B3/14 , A61F9/008 , A61F9/00804 , A61F2009/0087 , A61F2009/00872 , A61F2009/0088 , A61F2009/00895 , A61F2009/00897 , G02C7/041
Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.
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公开(公告)号：US20160135676A1
公开(公告)日：2016-05-19
申请号：US14956104
申请日：2015-12-01
Applicant: AMO Development, LLC
Inventor： Guang-ming Dai , Leander Zickler
CPC classification number: A61B3/0025 , A61B3/1015 , A61B3/107 , A61B3/112 , A61B3/14 , A61F9/008 , A61F9/00804 , A61F2009/0087 , A61F2009/00872 , A61F2009/0088 , A61F2009/00895 , A61F2009/00897 , G02C7/041
Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.
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公开(公告)号：US20150133900A1
公开(公告)日：2015-05-14
申请号：US14466701
申请日：2014-08-22
Applicant: AMO Development, LLC
Inventor： Guang-ming Dai , Leander Zickler
CPC classification number: A61B3/0025 , A61B3/1015 , A61B3/107 , A61B3/112 , A61B3/14 , A61F9/008 , A61F9/00804 , A61F2009/0087 , A61F2009/00872 , A61F2009/0088 , A61F2009/00895 , A61F2009/00897 , G02C7/041
Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.
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公开(公告)号：US09744077B2
公开(公告)日：2017-08-29
申请号：US14531716
申请日：2014-11-03
Applicant: AMO Development, LLC.
Inventor： Leander Zickler , Jim Deacon
CPC classification number: A61F9/008 , A61F2/16 , A61F2/1624 , A61F2/1629 , A61F9/0017 , A61F9/007 , A61F9/00834 , A61F2002/1681 , A61F2002/1699 , A61F2009/00848 , A61F2009/0087 , A61F2009/0088 , A61F2250/0006 , A61F2250/0008 , G02C2202/14
Abstract: A method of modifying a refractive profile of an eye having an intraocular device implanted therein, wherein the method includes determining a corrected refractive profile for the eye based on an initial refractive profile, identifying one or more locations within the intraocular device based on the corrected refractive profile, and directing a pulsed laser beam at the locations to produce the corrected refractive profile. A system of modifying an intraocular device located within an eye, wherein the system includes a laser assembly and a controller coupled thereto. The laser assembly outputs a pulsed laser beam having a pulse width between 300 picoseconds and 10 femtoseconds. The controller directs the laser assembly to output the pulsed laser beam into the intraocular device. One or more slip zones are formed within the intraocular device in response thereto, and the slip zones are configured to modify a refractive profile of the intraocular device.
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Patent Agency Ranking
公开(公告)号：US09198572B2
公开(公告)日：2015-12-01
申请号：US14466701
申请日：2014-08-22
Applicant: AMO Development, LLC
Inventor： Guang-ming Dai , Leander Zickler
CPC classification number: A61B3/0025 , A61B3/1015 , A61B3/107 , A61B3/112 , A61B3/14 , A61F9/008 , A61F9/00804 , A61F2009/0087 , A61F2009/00872 , A61F2009/0088 , A61F2009/00895 , A61F2009/00897 , G02C7/041
Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.
Abstract translation: 提供了用于获得患者眼睛的眼睛像差测量的方法和系统。 示例性技术包括获得与眼睛的第一容纳状态相对应的眼睛的第一诱导度量，获得与眼睛的第二适应状态对应的眼睛的第二诱导度量，以及确定眼睛的自然度量 关于第一和第二诱导度量。 诱导度量可以包括瞳孔尺寸或球面像差。 技术还可以包括基于自然度量确定眼睛的目标度量，确定眼睛的实际度量是否符合目标度量，如果实际度量符合目标度量，则获得眼睛的眼睛像差测量值，以及确定 基于眼睛像差测量治疗眼睛。
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7.发明申请Operator-Controlled Scanning Laser Procedure Designed for Large-Area Epithelium Removal 有权操作员控制扫描激光程序设计用于大面积上皮去除公开(公告)号：US20150088104A1
公开(公告)日：2015-03-26
申请号：US14558413
申请日：2014-12-02
Applicant: AMO Development, LLC.
Inventor： Mark E. Arnoldussen , Jonathan Wong , Benjamin A. Logan , Leander Zickler
IPC: A61F9/008
CPC classification number: A61F9/00814 , A61B2017/00057 , A61B2017/00154 , A61F9/008 , A61F9/00802 , A61F9/00817 , A61F2009/00844 , A61F2009/00846 , A61F2009/00848 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , A61F2009/00885 , A61F2009/00897
Abstract: Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such penetration of the epithelial layer can be detected.
Abstract translation: 用于去除设置在角膜上的基质层上的上皮层的系统和方法用消融辐射的脉冲束照射上皮层的区域。 根据脉冲序列扫描烧蚀辐射以改变该区域内的光束的位置。 布置脉冲序列以增强基于上皮层的组织荧光的光学反馈。 响应于光学反馈检测上皮层的穿透。 使用布置为增强光学反馈的脉冲序列的扫描允许大面积的上皮被消融，可以检测到上皮层的穿透。
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公开(公告)号：US20210315452A1
公开(公告)日：2021-10-14
申请号：US17304735
申请日：2021-06-24
Applicant: AMO Development, LLC
Inventor： Daniel R. Neal , Thomas D. Raymond , Leander Zickler
Abstract: Devices, systems, and methods that facilitate optical analysis, particularly for the diagnosis and treatment of refractive errors of the eye. An optical diagnostic method for an eye includes obtaining a sequence of aberration measurements of the eye, identifying an outlier aberration measurement of the sequence of aberration measurements, and excluding the outlier aberration measurement from the sequence of aberration measurements to produce a qualified sequence of aberration measurements. The sequence of aberrations measurements can be obtained by using a wavefront sensor. An optical correction for the eye can be formulated in response to the qualified sequence of aberration measurements.
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公开(公告)号：US11051688B2
公开(公告)日：2021-07-06
申请号：US16167292
申请日：2018-10-22
Applicant: AMO Development, LLC
Inventor： Daniel R. Neal , Thomas D. Raymond , Leander Zickler
Abstract: Devices, systems, and methods that facilitate optical analysis, particularly for the diagnosis and treatment of refractive errors of the eye. An optical diagnostic method for an eye includes obtaining a sequence of aberration measurements of the eye, identifying an outlier aberration measurement of the sequence of aberration measurements, and excluding the outlier aberration measurement from the sequence of aberration measurements to produce a qualified sequence of aberration measurements. The sequence of aberrations measurements can be obtained by using a wavefront sensor. An optical correction for the eye can be formulated in response to the qualified sequence of aberration measurements.
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公开(公告)号：US20160287066A1
公开(公告)日：2016-10-06
申请号：US15175179
申请日：2016-06-07
Applicant: AMO Development, LLC
Inventor： Guang-ming Dai , Leander Zickler
CPC classification number: A61B3/0025 , A61B3/1015 , A61B3/107 , A61B3/112 , A61B3/14 , A61F9/008 , A61F9/00804 , A61F2009/0087 , A61F2009/00872 , A61F2009/0088 , A61F2009/00895 , A61F2009/00897 , G02C7/041
Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.
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