TISSUE ADHESIVE COATINGS FOR DRUG COATED BALLOON
    2.
    发明申请
    TISSUE ADHESIVE COATINGS FOR DRUG COATED BALLOON 有权
    用于药物涂覆的气球的组合粘合剂涂料

    公开(公告)号:US20140277399A1

    公开(公告)日:2014-09-18

    申请号:US13842445

    申请日:2013-03-15

    Abstract: A therapeutic formulation is described for a drug delivery balloon comprising a therapeutic formulation which includes a therapeutic agent and an adhesion additive. The adhesion additive promotes adhesion of the therapeutic formulation a vessel wall of a subject. A system and a method of manufacturing a system including an expandable member having a working length with the therapeutic formulation disposed along at least a portion of the working length is also provided.

    Abstract translation: 描述了用于包含治疗剂的药物递送球囊的治疗剂型,其包括治疗剂和粘附添加剂。 粘合添加剂促进治疗剂对受试者血管壁的粘附。 还提供了一种制造系统和方法,其包括具有沿着工作长度的至少一部分设置的治疗剂的具有工作长度的可扩张构件的系统和方法。

    Polymers For Implantable Devices Exhibiting Shape-Memory Effects
    6.
    发明申请
    Polymers For Implantable Devices Exhibiting Shape-Memory Effects 审中-公开
    用于植入式装置的聚合物展示形状记忆效应

    公开(公告)号:US20140010858A1

    公开(公告)日:2014-01-09

    申请号:US13903773

    申请日:2013-05-28

    Abstract: The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.

    Abstract translation: 本发明涉及包含具有形状记忆特性的可生物降解的共聚物和由含有这种组合物的材料(例如涂层)形成的可植入装置(例如药物递送支架)的聚合物组合物。 聚合物组合物还可含有至少一种非结垢部分,至少另外的生物相容性聚合物,至少一种生物有益材料,至少一种生物活性剂或其组合。 将聚合物组合物配制成具有良好的机械,物理和生物学特性。 此外,由包含这种组合物的材料形成的可植入装置可以以方便的压缩尺寸输送到治疗部位,然后可扩大到适于其医疗功能的尺寸。

    METHOD AND MEDICAL DEVICE HAVING TISSUE ENGAGING MEMBER FOR DELIVERY OF A THERAPEUTIC AGENT
    9.
    发明申请
    METHOD AND MEDICAL DEVICE HAVING TISSUE ENGAGING MEMBER FOR DELIVERY OF A THERAPEUTIC AGENT 审中-公开
    具有用于递送治疗剂的组织结合部件的方法和医疗装置

    公开(公告)号:US20130138081A1

    公开(公告)日:2013-05-30

    申请号:US13741049

    申请日:2013-01-14

    Abstract: Method of delivering a therapeutic agent includes delivering at least a portion of a medical device within a vasculature. The medical device includes a tubular member having a proximal end and distal end defining a longitudinal axis therebetween, an expandable member proximate the distal end of the tubular member, a tissue engaging member proximate the expandable member, a sheath disposed over the tissue engaging member, and a therapeutic agent disposed on at least the expandable member or the tissue engaging member. The method further includes deploying the tissue engaging member at a select location by displacement of the sheath relative the tissue engaging member, inflating the expandable member to engage the therapeutic agent with a vessel wall, deflating the expandable member, and withdrawing the medical device from the vasculature.

    Abstract translation: 递送治疗剂的方法包括在脉管系统内输送医疗装置的至少一部分。 医疗装置包括管状构件,其具有限定其间的纵向轴线的近端和远端,靠近管状构件的远端的可扩张构件,靠近可膨胀构件的组织接合构件,设置在组织接合构件上方的护套, 以及设置在至少所述可扩张构件或所述组织接合构件上的治疗剂。 该方法还包括通过相对于组织接合构件移动护套来将组织接合构件部署在选择位置,使可膨胀构件膨胀以使治疗剂与血管壁接合,使可膨胀构件放气,以及将医疗装置从 脉管系统

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