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公开(公告)号:US20100105673A1
公开(公告)日:2010-04-29
申请号:US12518717
申请日:2007-12-08
申请人: Adrian Tersteegen , Dirk Heimbach , Kai Thede , Reinhold Welker , Beate Fast , Arnold Paessens , Frank Dittmer , Rudolf Schohe-Loop , Axel Harrenga , Alexander Hillisch , Kerstin Henninger , Walter Hübsch , Marcus Bauser , Susanne Greschat , Dirk Schneider , Tobias Marquardt , Andreas Göller , Andreas Urban , Steffen Wildum , Daniela Paulsen
发明人: Adrian Tersteegen , Dirk Heimbach , Kai Thede , Reinhold Welker , Beate Fast , Arnold Paessens , Frank Dittmer , Rudolf Schohe-Loop , Axel Harrenga , Alexander Hillisch , Kerstin Henninger , Walter Hübsch , Marcus Bauser , Susanne Greschat , Dirk Schneider , Tobias Marquardt , Andreas Göller , Andreas Urban , Steffen Wildum , Daniela Paulsen
IPC分类号: A61K31/365 , A61K31/5377 , A61K31/438 , C07D413/12 , C07D491/107 , C07D307/94 , A61P31/18 , A61P31/12
CPC分类号: C07D307/94 , C07D491/10
摘要: The present invention relates to novel substituted aminofurans, to methods for their preparation, to their use in the treatment and/or prophylaxis of diseases as well as their use in the manufacture of medical products for the treatment and/or prophylaxis of diseases, in particular retroviral disorders, in humans and/or animals.
摘要翻译: 本发明涉及新型取代的氨基呋喃,其制备方法,其用于治疗和/或预防疾病及其在制备用于治疗和/或预防疾病的医药产品中的用途,特别是 逆转录病毒疾病,在人和/或动物中。
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公开(公告)号:US08318761B2
公开(公告)日:2012-11-27
申请号:US12203793
申请日:2008-09-03
申请人: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
发明人: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC分类号: A01N43/40 , A61K31/435 , A61K31/44
CPC分类号: C07D413/04 , C07D213/73
摘要: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译: 本发明涉及式(I)的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途,特别是用作抗病毒剂,特别是用于巨细胞病毒的药物。
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公开(公告)号:US20090176842A1
公开(公告)日:2009-07-09
申请号:US12203793
申请日:2008-09-03
申请人: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
发明人: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC分类号: A61K31/4439 , C07D413/04 , C07D213/73 , A61P31/12
CPC分类号: C07D413/04 , C07D213/73
摘要: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译: 本发明涉及式(I)的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途,特别是用作抗病毒剂,特别是用于巨细胞病毒的药物。
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公开(公告)号:US20100184740A1
公开(公告)日:2010-07-22
申请号:US12665729
申请日:2008-06-07
申请人: Swen Allerheiligen , Marcus Bauser , Dirk Heimbach , Stefan Heitmeier , Mark Jean Gnoth , Christoph Gerdes , Georges Von Degenfeld , Susanne Röhrig , Ulrich Rester , Elke Dittrich-Wengenroth , Uwe Saatman , Adrian Tersteegen
发明人: Swen Allerheiligen , Marcus Bauser , Dirk Heimbach , Stefan Heitmeier , Mark Jean Gnoth , Christoph Gerdes , Georges Von Degenfeld , Susanne Röhrig , Ulrich Rester , Elke Dittrich-Wengenroth , Uwe Saatman , Adrian Tersteegen
IPC分类号: A61K31/4439 , C07D413/14 , A61K31/5377 , A61K31/496 , C07D417/14 , A61K31/541 , A61K31/553 , A61P7/02 , A61P7/00 , A61P9/12 , A61P29/00
CPC分类号: C07D413/14
摘要: The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
摘要翻译: 本发明涉及新的取代的恶唑烷酮,其制备方法,其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是血栓栓塞性疾病的药物的用途。
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公开(公告)号:US08383822B2
公开(公告)日:2013-02-26
申请号:US12665729
申请日:2008-06-07
申请人: Swen Allerheiligen , Marcus Bauser , Dirk Heimbach , Stefan Heitmeier , Mark Jean Gnoth , Christoph Gerdes , Georges Von Degenfeld , Susanne Röhrig , Ulrich Rester , Elke Dittrich-Wengenroth , Uwe Saatmann , Adrian Tersteegen , Joachim Krüger , Holger Paulsen
发明人: Swen Allerheiligen , Marcus Bauser , Dirk Heimbach , Stefan Heitmeier , Mark Jean Gnoth , Christoph Gerdes , Georges Von Degenfeld , Susanne Röhrig , Ulrich Rester , Elke Dittrich-Wengenroth , Uwe Saatmann , Adrian Tersteegen , Joachim Krüger , Holger Paulsen
IPC分类号: A61K31/44 , C07D413/00
CPC分类号: C07D413/14
摘要: The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
摘要翻译: 本发明涉及新的取代的恶唑烷酮,其制备方法,其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是血栓栓塞性疾病的药物的用途。
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公开(公告)号:US20080004275A1
公开(公告)日:2008-01-03
申请号:US10594343
申请日:2005-03-11
申请人: Holger Zimmermann , David Bruckner , Dirk Heimbach , Martin Hendrix , Kerstin Henninger , Guy Hewlett , Ulrich Rosentreter , Jorg Keldenich , Dieter Lang , Martin Radtke
发明人: Holger Zimmermann , David Bruckner , Dirk Heimbach , Martin Hendrix , Kerstin Henninger , Guy Hewlett , Ulrich Rosentreter , Jorg Keldenich , Dieter Lang , Martin Radtke
IPC分类号: A61K31/5377 , A61K31/4155 , A61K31/4178 , A61K31/4184 , A61P31/12 , C07D233/88 , C07D249/12 , C07D403/12 , C07D413/12 , C07D401/12 , C07D249/04 , C07D233/44 , A61K31/4192 , A61K31/4196 , A61K31/4439
CPC分类号: C07D233/90 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要: The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
摘要翻译: 本发明涉及式(I)的取代的咪唑及其制备方法,用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病的药物的用途 特别是用作抗病毒药物,特别是针对巨细胞病毒。
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公开(公告)号:US07767704B2
公开(公告)日:2010-08-03
申请号:US10594343
申请日:2005-03-11
申请人: Holger Zimmermann , David Brueckner , Dirk Heimbach , Martin Hendrix , Kerstin Henninger , Guy Hewlett , Ulrich Rosentreter , Joerg Keldenich , Dieter Lang , Martin Radtke
发明人: Holger Zimmermann , David Brueckner , Dirk Heimbach , Martin Hendrix , Kerstin Henninger , Guy Hewlett , Ulrich Rosentreter , Joerg Keldenich , Dieter Lang , Martin Radtke
IPC分类号: A61K31/4164 , C07D233/54
CPC分类号: C07D233/90 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要: The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
摘要翻译: 本发明涉及式(I)的取代的咪唑及其制备方法,用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病的药物的用途 特别是用作抗病毒剂,特别是抗巨细胞病毒。
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公开(公告)号:US08987248B2
公开(公告)日:2015-03-24
申请号:US13202707
申请日:2010-03-12
申请人: Mario Jeske , Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Kersten Matthias Gericke
发明人: Mario Jeske , Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Kersten Matthias Gericke
IPC分类号: A61K31/5377 , C07D413/06 , C07D211/60 , C07D211/42 , C07D211/56 , C07D211/62 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/06
CPC分类号: C07D417/06 , A61K9/0019 , A61K9/10 , A61K9/2018 , A61K31/451 , A61K31/4523 , A61K31/4525 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K47/10 , A61K47/36 , C07D211/42 , C07D211/56 , C07D211/60 , C07D211/62 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12
摘要: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumor disorders.
摘要翻译: 本发明涉及新的取代的哌啶,其制备方法,其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是心血管疾病和肿瘤的药物的用途 疾病
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公开(公告)号:US20120046268A1
公开(公告)日:2012-02-23
申请号:US13202707
申请日:2010-03-12
申请人: Mario Jeske , Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Kersten Matthias Gericke
发明人: Mario Jeske , Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Kersten Matthias Gericke
IPC分类号: A61K31/4523 , C07D405/06 , C07D401/06 , C07D417/06 , C07D413/06 , A61K31/445 , A61K31/453 , A61K31/4525 , A61K31/454 , A61K31/4545 , A61K31/5377 , A61K31/496 , A61K31/541 , A61P7/02 , C12N5/078 , C07D211/60
CPC分类号: C07D417/06 , A61K9/0019 , A61K9/10 , A61K9/2018 , A61K31/451 , A61K31/4523 , A61K31/4525 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K47/10 , A61K47/36 , C07D211/42 , C07D211/56 , C07D211/60 , C07D211/62 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12
摘要: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumour disorders.
摘要翻译: 本发明涉及新的取代的哌啶,其制备方法,其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是心血管疾病和肿瘤的药物的用途 疾病
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公开(公告)号:US20120214788A1
公开(公告)日:2012-08-23
申请号:US13400491
申请日:2012-02-20
申请人: Dirk Heimbach , Susanne Röhrig , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Yolanda Cancho Grande , Mario Jeske , Kersten Matthias Gericke
发明人: Dirk Heimbach , Susanne Röhrig , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Yolanda Cancho Grande , Mario Jeske , Kersten Matthias Gericke
IPC分类号: A61K31/454 , A61P9/10 , A61P7/00 , A61K31/5377 , A61K31/4545
CPC分类号: C07D413/04 , C07D413/14 , C07D417/14
摘要: The invention relates to novel heteroaryl-substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular diseases and tumour diseases.
摘要翻译: 本发明涉及新颖的杂芳基取代的哌啶,其制备方法,其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是心血管疾病的药物的用途 和肿瘤疾病。
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