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公开(公告)号：US4582681A
公开(公告)日：1986-04-15
申请号：US435662
申请日：1982-10-21
申请人： Akira Asari , Shiro Matsuura , Hidehiro Tsuzuki , Yohichi Inoue , Masato Moritoki , Takao Fujikawa , Junichi Miyanaga
发明人： Akira Asari , Shiro Matsuura , Hidehiro Tsuzuki , Yohichi Inoue , Masato Moritoki , Takao Fujikawa , Junichi Miyanaga
CPC分类号： B30B11/002 , B22F3/15 , B28B3/006
摘要： A hot isostatic pressing system including a hot isostatic pressing station having a high pressure container constituted by a vertical pressure-resistant cylinder closed at the top end thereof and a lower lid detachably fitted to the bottom of the pressure resistant cylinder and a treating chamber internally provided with a heater and enclosed by a heat insulating wall, and a mechanism for adjusting an atmospheric gas pressure and temperature of the pressing station into a condition suitable for the hot isostatic pressing of a work item accommodated in the treating chamber; a plurality of auxiliary stations each provided with an opening for receiving from beneath thereof the heat insulating wall of the treating chamber accommodating the internal heater and a work item, a support structure for supporting the heat insulating wall, and a mechanism for cooling the work item and internal heater in an inert gas atmosphere; a carriage for transferring the lower lid and work item or the lower lid, work item, heat insulating wall and internal heater between the hot isostatic pressing station and one of the auxiliary stations; and a lift mechanism for lifting up and down the lower lid and work item or the lower lid, work item, heat insulating wall and heater at the hot isostatic pressing station and each one of the auxiliary stations.
摘要翻译： 一种热等静压按压系统，包括具有高压容器的热等静压按压站，所述高压容器由其顶端封闭的垂直耐压圆筒和可拆卸地装配到耐压圆筒底部的下盖以及内部设置的处理室 具有加热器并由绝热壁包围的机构，以及用于将加压站的气氛气体压力和温度调节到适于对容纳在处理室中的工件进行热等静压的状态的机构; 多个辅助站各自具有开口，用于从其下方接收容纳内部加热器的处理室的隔热壁和工件，用于支撑隔热壁的支撑结构和用于冷却工件的机构 和内部加热器在惰性气体气氛中; 用于在热等静压按压站和辅助站之间传送下盖和工作物品或下盖，工件，隔热墙和内部加热器的托架; 以及一个提升机构，用于在热等静压站和每个辅助站上下下盖和工作物品或下盖，工件，隔热墙和加热器。
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公开(公告)号：US4537569A
公开(公告)日：1985-08-27
申请号：US555620
申请日：1983-11-28
申请人： Akira Asari , Hidehiro Tsuzuki , Yoichi Inoue , Takahisa Tabuchi
发明人： Akira Asari , Hidehiro Tsuzuki , Yoichi Inoue , Takahisa Tabuchi
CPC分类号： B22F3/15 , B22F3/03 , B30B11/001 , B65H39/11
摘要： A hot isostatic pressing apparatus equipped with at least one hot isostatic pressing vessel having a detachable bottom lid and at least one cooling or preheating cylinder or hot isostatic pressing vessel arranged substantially on a central horizontal extension of the former vessel, which apparatus includes a rail provided in front of the former vessel and cylinder or the latter vessel with an interval between the rail and the former vessel and the cylinder or the latter vessel; and a carrier capable of reciprocally travelling between the former vessel and the cylinder or the latter vessel and including a lift frame, a lift provided with the frame and a bottom lid cradle, the cradle being provided in the form of a cantilever with lift and extending to a point underneath the former vessel when the carrier assumes a position in front of the former vessel and to another point underneath the cylinder or the latter vessel when the carrier assumes a position in front of the cylinder or the latter vessel. The above construction permits smooth and free travelling of the carrier and facilitates the overall size reduction and maintenance of the HIP apparatus. Only one carrier is required even if a plurality of HIP vessels or a plurality of HIP vessels and preheating/cooling cylinders is provided so as to improve production efficiency.
摘要翻译： 一种装备有至少一个具有可拆卸底盖的热等静压按压容器的热等静压装置，以及基本上设置在前容器的中心水平延伸部上的至少一个冷却或预热气缸或热等静压按压容器，该装置包括一轨道 在前容器和气缸或后一个容器的前面，在轨道与前一个容器和气缸或后一个容器之间具有间隔; 以及能够在前一个船舶与缸或后者船之间往复行进的承载件，并且包括升降机架，设置有框架的升降机和底盖支架，所述托架以悬臂形式提供并延伸 当承运人在汽缸或后者船只前面的位置时，承运人承担前一船只前方的位置，以及在汽缸或后者船只下方的另一点，到前一船只下方。 上述结构允许载体的平稳和自由的行进，并且有助于HIP装置的整体尺寸减小和维护。 即使设置多个HIP容器或多个HIP容器和预热/冷却气缸，也只需要一个载体，以提高生产效率。
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公开(公告)号：US4112723A
公开(公告)日：1978-09-12
申请号：US798572
申请日：1977-05-19
申请人： Akira Asari , Hidehiro Tsuzuki
发明人： Akira Asari , Hidehiro Tsuzuki
CPC分类号： B21C23/217 , B21C23/007
摘要： A hydrostatic extrusion process and an apparatus therefor includes a mandrel and a stem which are movable independently of each other, and a seal block which is utilized for increasing the pressure of the pressure medium for performance of the extrusion operation of the billet. A supply device pre-disposes an extrusion die, a billet, pressure medium, and a seal block within a supply unit or sleeve and is capable of being moved from a position exterior of the extrusion apparatus station to a position corresponding to the extrusion station, and in this manner, the time period required for completing extrusion cycles is substantially reduced. Still further, a locking mechanism, including a locking slide and a locking plate, are operatively associated with the mandrel for controlling or limiting the axial movement of the mandrel so as to in turn control the loading and tensioning of the same in order to prevent damage thereto.
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公开(公告)号：US4083214A
公开(公告)日：1978-04-11
申请号：US629891
申请日：1975-11-07
申请人： Akira Asari , Hidehiro Tsuzuki
发明人： Akira Asari , Hidehiro Tsuzuki
IPC分类号： B21C23/00
CPC分类号： B21C23/007
摘要： A hydrostatic extrusion process and an apparatus therefor includes a mandrel and a stem which are movable independently of each other, and a seal block which is utilized for increasing the pressure of the pressure medium for performance of the extrusion operation of the billet. A supply device pre-disposes an extrusion die, a billet, pressure medium, and a seal block within a supply unit or sleeve and is capable of being moved from a position exterior of the extrusion apparatus station to a position corresponding to the extrusion station, and in this manner, the time period required for completing extrusion cycles is substantially reduced. Still further, a locking mechanism, including a locking slide and a locking plate, are operatively associated with the mandrel for controlling or limiting the axial movement of the mandrel so as to in turn control the loading and tensioning of the same in order to prevent damage thereto.
摘要翻译： 一种静压挤出工艺及其设备包括一个彼此独立运动的心轴和一个杆，以及一个用于提高压力介质压力的密封块，用于执行坯料的挤压操作。 供给装置在供给单元或套筒内预先设置挤出模具，坯料，压力介质和密封块，并且能够从挤出设备站的外部位置移动到与挤出站对应的位置， 并且以这种方式，完成挤出循环所需的时间段显着降低。 此外，包括锁定滑块和锁定板的锁定机构与心轴可操作地相关联，用于控制或限制心轴的轴向运动，从而进而控制心轴的加载和张紧，以防止损坏 到此。
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公开(公告)号：US4443143A
公开(公告)日：1984-04-17
申请号：US355341
申请日：1982-03-08
申请人： Akira Asari , Tatsuhiko Noyori , Hidehiro Tsuzuki , Takahisa Tabuchi , Tsuneharu Masuda , Tetsuro Takehata, deceased
发明人： Akira Asari , Tatsuhiko Noyori , Hidehiro Tsuzuki , Takahisa Tabuchi , Tsuneharu Masuda , Tetsuro Takehata, deceased
CPC分类号： B21C35/06 , B21C43/00 , Y10S83/914 , Y10T29/4561 , Y10T409/501148 , Y10T409/50164 , Y10T409/50328 , Y10T409/503608
摘要： A billet scalper including a die assembly with a scalping die, a pressing mechanism with a stem member in axial alignment with the scalping die for pressing a billet thereinto, and a chip ejector located around the circumference of the scalping die and movable axially back and forth beyond a free end face of the scalping die to remove chips therefrom. The die assembly including the scalping die is movable between a position at the center of the scalper and an outer receded position to permit easy maintenance and service of the die assembly including replacements and cleaning of scalping dies. In a preferred form, the scalper is constructed integrally with an extrusion press to perform the billet scalping operation in timed relation with the extruding operation to shorten the time of press cycle.
摘要翻译： 一种包括具有剥皮模具的模具组件的冲压机，具有与用于将坯料挤压的切割模具轴向对准的杆部件的按压机构，以及位于烫金模具的圆周周围并且可轴向运动的芯片喷射器 超过烫金模具的自由端面，以从中除去芯片。 包括烫伤模具的模具组件可在切割器中心的位置和外部退回位置之间移动，以允许容易地维护和维护模具组件，包括替换和清洁烫伤模具。 在优选形式中，定型机与挤压机一体地构造，以与挤压操作定时关系进行坯料切割操作，以缩短压制周期。
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公开(公告)号：US4484881A
公开(公告)日：1984-11-27
申请号：US572051
申请日：1984-01-19
申请人： Akira Asari , Tamotsu Fukuda , Shiro Matsuura
发明人： Akira Asari , Tamotsu Fukuda , Shiro Matsuura
CPC分类号： B30B11/002 , B22F3/15 , B30B11/001
摘要： A hot isostatic pressing apparatus including a high pressure container having an opening at least at one end thereof for loading and unloading materials or products being formed. The high pressure container is internally provided with a heat insulator and a heater. A container holding frame has an open space substantially at the center thereof for releasably holding the upper and lower ends of the high pressure container during the hot isostatic pressing stage of the operation. The container holding frame is movably supported at one side thereof on a stationary structure for movements toward and away from the high pressure container.
摘要翻译： 一种热等静压装置，包括至少在其一端具有用于装载和卸载正在形成的材料或产品的开口的高压容器。 高压容器内部设有绝热器和加热器。 容器保持框架具有大致在其中心的开放空间，用于在操作的热等静压阶段期间可释放地保持高压容器的上端和下端。 容器保持框架在其一侧可移动地支撑在固定结构上以朝向和远离高压容器移动。
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公开(公告)号：US07507723B2
公开(公告)日：2009-03-24
申请号：US10312879
申请日：2001-07-06
申请人： Akira Asari , Hitoshi Kurihara , Tomomi Shibata , Yuka Miyazaki , Hiroko Yamanokuchi , Akira Tawada , Takahiro Masa , Yuji Matsuzaki
发明人： Akira Asari , Hitoshi Kurihara , Tomomi Shibata , Yuka Miyazaki , Hiroko Yamanokuchi , Akira Tawada , Takahiro Masa , Yuji Matsuzaki
IPC分类号： A61K31/702 , A61K31/728
CPC分类号： C08B37/0072 , A61K31/702 , A61K31/728 , C07H7/033
摘要： Hyaluronic acid oligosaccharides having a size selected from sizes of 4 to 60 saccharides, fractions containing the hyaluronic acid oligosaccharides and having particular physicochemical properties, and drugs containing the same. The hyaluronic acid oligosaccharides of the present invention are extremely useful, because they exert superior pharmaceutical effects as active ingredients of a heat shock protein expression promoter, cell death inhibitor, cell injury inhibitor and cell and tissue protecting agent (e.g., organ preservation agent, antiulcer agent, antihepatopathic agent, IL-10 production promoter or IL-8 production inhibitor) and exhibit high safety.
摘要翻译： 具有选自尺寸为4至60个糖的大小的透明质酸寡糖，含有透明质酸寡糖的部分并且具有特定的理化性质，以及含有该物质的药物。 本发明的透明质酸寡糖是非常有用的，因为它们作为热休克蛋白表达启动子，细胞死亡抑制剂，细胞损伤抑制剂和细胞和组织保护剂（例如器官保存剂，抗溃疡剂）的活性成分发挥优异的药物作用 药物，抗肝病，IL-10生产促进剂或IL-8产生抑制剂），并表现出高安全性。
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公开(公告)号：US06436911B1
公开(公告)日：2002-08-20
申请号：US09620747
申请日：2000-07-21
IPC分类号： A01N4304
CPC分类号： A61K31/7024
摘要： An IL-12 production inhibitor which comprises, as an active ingredient, a keratan sulfate oligosaccharide or a derivative thereof, for example, a keratan sulfate oligosaccharide comprising at least one repeating unit of either one of the disaccharides represented by the following formulas: Gal (6s)-GlcNAc (6s) and Gal (6s)-GlcNAc wherein Gal represents a galactose residue, GlcNAc represents an N-acetylglucosamine residue, 6s indicates that 6-0-sulfate ester is formed at a Hydroxyl group at the 6-position, and - represents a glycosidic linkage.
摘要翻译： 作为活性成分的含有硫酸角质素寡糖或其衍生物的IL-12产生抑制剂，例如硫酸角质素寡糖，其包含由下式表示的二糖中的至少一个重复单元：Gal（ 6s）-GlcNAc（6s）和Gal（6s）-GlcNAc，其中Gal表示半乳糖残基，GlcNAc表示N-乙酰葡糖胺残基，6s表示6位羟基上形成6-0-硫酸酯， 和 - 表示糖苷键。
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9.发明授权Carbon fiber reinforced carbon composite and useful as components for pulling single crystal apparatus 有权碳纤维增强碳复合材料，用作牵引单晶装置的部件公开(公告)号：US06432538B1
公开(公告)日：2002-08-13
申请号：US09493016
申请日：2000-01-28
申请人： Toshiharu Hiraoka , Naoto Ohta , Akira Asari , Toshiaki Sogabe
发明人： Toshiharu Hiraoka , Naoto Ohta , Akira Asari , Toshiaki Sogabe
IPC分类号： B32B900
CPC分类号： C30B15/10 , C30B35/002 , Y10S428/902 , Y10T428/249928 , Y10T428/2933 , Y10T428/30
摘要： A carbon fiber reinforced carbon composite, obtained by a method comprising impregnating a pitch or a resin into a molded member formed of carbon fibers for densification thereof; forming an impregnated pyrolytic carbon layer by CVI after densification; and forming a coated pyrolytic carbon layer on the impregnated pyrolytic carbon layer by CVD; a method of making the carbon fiber reinforced carbon composite; and a pulling single crystal member made from the carbon fiber reinforced carbon composite.
摘要翻译： 一种碳纤维增强碳复合材料，其通过将沥青或树脂浸渍到由碳纤维形成的模制构件中以使其致密化的方法获得; 在致密化后通过CVI形成浸渍的热解碳层; 并通过CVD在浸渍的热解碳层上形成涂层的热解碳层; 制造碳纤维增强碳复合材料的方法; 以及由碳纤维增强碳复合材料制成的拉制单晶构件。
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10.发明授权
公开(公告)号：US4777814A
公开(公告)日：1988-10-18
申请号：US285287
申请日：1981-07-20
申请人： Akira Asari , Tsuneharu Masuda
发明人： Akira Asari , Tsuneharu Masuda
CPC分类号： B21C35/06 , B21C23/218 , B21C35/00
摘要： Method and apparatus for removing a jammed billet from a container on a metal extrusion press in which a billet in a container is extruded through a die at the fore end of a die stem by relative movement of the die stem admitted into the container while the billet and container are held stationary relative to each other. Should the billet in the container jam, pressure is applied on the rear end face of the billet in the axial pressing direction thereby extruding the billet in the counter-pressing axial direction.
摘要翻译： 用于从金属挤压机上的容器中取出卡住的坯料的方法和装置，其中通过容纳在容器中的模头的相对运动将容器中的坯料挤出通过模头前端的模具，同时坯料 并且容器相对于彼此保持静止。 如果容器中的坯料堵塞，则沿着轴向按压方向对坯料的后端面施加压力，从而沿反向挤压轴向挤压坯料。
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