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1.2-amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors 有权
标题翻译: 2-氨基-3-(咪唑-2-基) - 吡啶-4-酮衍生物及其作为VEGF受体激酶抑制剂的用途公开(公告)号:US09126972B2
公开(公告)日:2015-09-08
申请号:US14117750
申请日:2012-05-16
申请人: Alain Braun , Olivier Duclos , Gilbert Lassalle , Franz Lorge , Valerie Martin , Olaf Ritzeler , Aurelie Strub
发明人: Alain Braun , Olivier Duclos , Gilbert Lassalle , Franz Lorge , Valerie Martin , Olaf Ritzeler , Aurelie Strub
IPC分类号: C07D471/04 , C07D401/14 , C07D401/04 , A61K31/4709 , A61K31/4375 , A61K45/06
CPC分类号: A61K31/4709 , A61K31/4375 , A61K45/06 , C07D401/04 , C07D471/04
摘要: The invention relates to the compounds of general formula (I): Preparation process and therapeutic use.
摘要翻译: 本发明涉及通式(I)的化合物:制备方法和治疗用途。
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2.Pyridinopyridinone derivatives, preparation thereof and therapeutic use thereof 有权
标题翻译: 吡啶并吡啶酮衍生物,其制备及其治疗用途公开(公告)号:US08436011B2
公开(公告)日:2013-05-07
申请号:US12985749
申请日:2011-01-06
申请人: Patrice Bellevergue , Gilbert Lassalle , Gary McCort , Valerie Martin , Pierre Savi , Cecile Volle-Challier
发明人: Patrice Bellevergue , Gilbert Lassalle , Gary McCort , Valerie Martin , Pierre Savi , Cecile Volle-Challier
IPC分类号: A61K31/4375 , C07D471/06
CPC分类号: C07D471/04
摘要: The present invention relates to pyridopyridone derivatives of formula (I): in which the variables are as defined herein, to their preparation and to their therapeutic use as inhibitors of the kinase activity of PDGF (platelet-derived growth factor) ligand receptors and possibly of FLT3 (fms-like tyrosine kinase receptor) ligand receptors.
摘要翻译: 本发明涉及式(I)的吡啶并吡啶酮衍生物:其中变量如本文所定义,其制备及其治疗用途作为PDGF(血小板衍生生长因子)配体受体的激酶活性的抑制剂以及可能的 FLT3(fms样酪氨酸激酶受体)配体受体。
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