公开(公告)号：US20180265474A1

公开(公告)日：2018-09-20

申请号：US15924005

申请日：2018-03-16

Applicant: Aldeyra Therapeutics, Inc.

Inventor： Amanda BUIST ,  Eden FUCCI ,  Stephen G. MACHATHA ,  Osama SULEIMAN ,  Kate WITTERING

IPC: C07D215/38 ,  C07C309/04 ,  A61K31/47 ,  C07C309/29 ,  C07C55/07 ,  C07C309/25 ,  C07C59/255

Abstract: The present invention provides freebase and salt forms, and compositions and methods thereof, useful for treating various conditions, in which aldehyde toxicity is implicated in the pathogenesis, by the administration of small molecule therapeutics acting as a scavenger for toxic aldehydes.