利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

4 条记录 (耗时 0.026 秒)

    Microscopic precision construction of tissue array block related application data
    3.
    发明申请
    Microscopic precision construction of tissue array block related application data 审中-公开
    组织阵列块微观精密结构相关应用数据

    公开(公告)号：US20060099653A1

    公开(公告)日：2006-05-11

    申请号：US11302633

    申请日：2005-12-13

    申请人： Page Erickson ,  Eugene Mechetner ,  Valeriy Katsnelson ,  Norm Turoff

    发明人： Page Erickson ,  Eugene Mechetner ,  Valeriy Katsnelson ,  Norm Turoff

    IPC分类号： G01N33/567 ,  G01N1/30 ,  G01N33/53 ,  G01N33/48

    CPC分类号： G01N1/36 ,  G01N2001/368

    摘要： This present invention covers novel means, devices and instruments for production of a tissue array block that is further sectioned into duplicates of tissue arrays. An integral microscope is incorporated into the instrument for viewing and examining a stained reference slide and selecting donor tissue core region(s) from the reference slide. The reference slide is held in a reference slide station that is operatively linked and indexed with a station or platform holding a source donor tissue block, which is further indexed and precisely positioned with reference to the donor needle punch for punching the donor tissue core(s). A recipient block indexed to the donor block punch is placed under the donor punch station and donor tissue cores are delivered into pre-existing hole(s) by a stylet to construct the tissue array block. The instrument includes a donor punch station, optionally a second recipient punch station, with each operable independently or removable. The present invention also provides pre-loading needles with donor tissue cores for constructing tissue array blocks in pre-gridded and pre-punched recipient block. The tissue arrays produced from the tissue array blocks made are useful for testing such freshly-made and/or archival tissue specimens in both scientific and clinical research and applications.

    摘要翻译： 本发明涵盖用于生产组织阵列块的新颖的装置和装置，其进一步分成组织阵列的重复部分。 将整体显微镜并入仪器中，用于观察和检查染色的参考幻灯片并从参考幻灯片中选择供体组织核心区域。 参考滑块被保持在参考滑动台中，该参考滑动台可操作地连接并且用固定源供体组织块的工位或平台进行分度，所述工位或平台相对于施主针冲头被进一步分度和精确地定位，以冲压供体组织芯 ）。 将供体块冲头引导到受体块被放置在供体穿孔位置下，并且通过探针将供体组织芯递送到预先存在的孔中以构建组织阵列块。 该仪器包括供体穿孔台，可选地是第二受体穿孔台，每个可独立地操作或可移除。 本发明还提供了具有供体组织芯的预加载针，用于在预网格和预先冲压的受体块中构建组织阵列块。 从制造的组织阵列块产生的组织阵列可用于在科学和临床研究和应用中测试这些新鲜制备和/或归档组织标本。

    Method and apparatus for controllably aspirating fluids from surgical sites
    4.
    发明申请
    Method and apparatus for controllably aspirating fluids from surgical sites 审中-公开
    从外科手术部位可控地吸入液体的方法和装置

    公开(公告)号：US20050245903A1

    公开(公告)日：2005-11-03

    申请号：US10836446

    申请日：2004-04-29

    申请人： Yevgeniy Kuklin ,  Norm Turoff

    发明人： Yevgeniy Kuklin ,  Norm Turoff

    IPC分类号： A61K9/22

    CPC分类号： A61M1/0031 ,  A61F9/00736 ,  A61M1/0027 ,  A61M1/0029 ,  A61M1/0072 ,  A61M2205/3331

    摘要： A surgical aspiration system and the method of using the same for aspirating fluid from a surgical site at a desired aspiration rate. The system includes an interface component for providing an interface with the surgical site; a variable rate pump operably associated with the interface component for controllably generating a vacuum at the surgical site to cause a flow of fluids from the surgical site; a collector chamber interconnected with the interface component and with the pump for collecting liquids flowing from the surgical site; and a control system operably associated with the pump for controlling the pumping rate thereof in a manner to maintain the desired aspiration rate at the surgical site, the control system including a sensor for sensing a change in vacuum at the interface component due to liquid entering the interface component and for controlling the pumping rate of the pump in response thereto.

    摘要翻译： 手术抽吸系统及其使用方法，用于以期望的抽吸速率从外科手术部位抽吸流体。 该系统包括用于提供与手术部位的界面的接口部件; 可操作地与所述界面部件相关联的可变速率泵，用于在所述外科手术部位处可控制地产生真空以引起来自所述手术部位的流体流动; 与界面部件相互连接的收集器室和用于收集从外科手术部位流出的液体的泵; 以及与所述泵可操作地相关联的控制系统，以便以维持所述外科手术部位的期望吸气速率的方式控制其泵送速率，所述控制系统包括用于感测由于液体进入所述接口部件而导致的界面部件处的真空变化的传感器 并且用于响应于此控制泵的泵送速率。