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公开(公告)号:US08486936B2
公开(公告)日:2013-07-16
申请号:US12773656
申请日:2010-05-04
申请人: Alexander Khvat , Sergey Tkachenko , Ilya Okun , Borys Rogovoy , Nikolay Savchuk , John May , Patrick O'Connor , William Ripka , Jean-Michel Vernier , David Matthews
发明人: Alexander Khvat , Sergey Tkachenko , Ilya Okun , Borys Rogovoy , Nikolay Savchuk , John May , Patrick O'Connor , William Ripka , Jean-Michel Vernier , David Matthews
IPC分类号: A61K31/5377 , A61K31/497 , A61K31/437 , C12N5/02 , C07D471/04 , A61P35/00
CPC分类号: C07D471/04
摘要: Described herein are compounds, pharmaceutical compositions and methods for the inhibition of Hedgehog signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human and veterinary diseases and disorders.
摘要翻译: 本文描述了用于抑制Hedgehog信号传导的化合物,药物组合物和方法。 所述化合物,药物组合物和方法可用于治疗人和兽医疾病和病症。