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公开(公告)号:US20120058989A1
公开(公告)日:2012-03-08
申请号:US13082269
申请日:2011-04-07
申请人: Allan S. Wagman , Heinz E. Moser , Glenn A. McEnroe , James B. Aggen , Martin S. Linsell , Adam A. Goldblum , John H. Griffin , Lloyd J. Simons , Thomas R. Belliotti , Christina R. Harris , Toni-Jo Poel , Michael J. Melnick , Ricky D. Gaston
发明人: Allan S. Wagman , Heinz E. Moser , Glenn A. McEnroe , James B. Aggen , Martin S. Linsell , Adam A. Goldblum , John H. Griffin , Lloyd J. Simons , Thomas R. Belliotti , Christina R. Harris , Toni-Jo Poel , Michael J. Melnick , Ricky D. Gaston
IPC分类号: A61K31/553 , A61P31/04 , C07D498/14 , C07D471/14 , A61K31/55 , A61K31/5517
CPC分类号: C07D471/14 , C07D498/14 , C07D513/14
摘要: Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein A, B, D, E, G, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
摘要翻译: 公开了具有抗菌活性的化合物。 该化合物具有以下结构(I):包括其立体异构体,药学上可接受的盐和前药,其中A,B,D,E,G,R 1,R 2,R 3,R 4,R 5,R 6和R 7如本文所定义。 还公开了与这种化合物的制备和使用相关的方法以及包含这些化合物的药物组合物。