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公开(公告)号：US07959666B2
公开(公告)日：2011-06-14
申请号：US10982388
申请日：2004-11-05
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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公开(公告)号：US20120016469A1
公开(公告)日：2012-01-19
申请号：US13157733
申请日：2011-06-10
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D. Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D. Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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公开(公告)号：US07988724B2
公开(公告)日：2011-08-02
申请号：US11706549
申请日：2007-02-14
申请人： Amr Salahieh , Hans F. Valencia , Brian D. Brandt , Claudio Argento , Ulrich R. Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight P. Morejohn , Tom Saul
发明人： Amr Salahieh , Hans F. Valencia , Brian D. Brandt , Claudio Argento , Ulrich R. Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight P. Morejohn , Tom Saul
CPC分类号： A61F2/2427 , A61B17/0644 , A61B17/068 , A61B17/221 , A61B2017/22035 , A61B2017/2215 , A61F2/2409 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/90 , A61F2002/9534 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0078 , A61F2230/008 , A61F2250/001
摘要： The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
摘要翻译： 本发明涉及用于在患者的天然心脏瓣膜内和/或穿过患者的天然心脏瓣膜内血管内递送和释放假体（例如主动脉假体）的装置和方法，以下称为替换患者的心脏瓣膜。 在一些实施例中，递送系统包括多个第一致动元件，其适于以第一构造接合多个第二元件以在输送系统内捕获植入物，并且其中多个第一可致动元件适于接合多个第二可动元件 元件处于第二配置并且从输送系统释放植入物。
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公开(公告)号：US08858620B2
公开(公告)日：2014-10-14
申请号：US13157733
申请日：2011-06-10
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D. Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D. Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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公开(公告)号：US20110257735A1
公开(公告)日：2011-10-20
申请号：US13166184
申请日：2011-06-22
申请人： Amr Salahieh , Hans F. Valencia , Brian D. Brandt , Claudio Argento , Ulrich R. Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight P. Morejohn , Tom Saul
发明人： Amr Salahieh , Hans F. Valencia , Brian D. Brandt , Claudio Argento , Ulrich R. Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight P. Morejohn , Tom Saul
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61B17/0644 , A61B17/068 , A61B17/221 , A61B2017/22035 , A61B2017/2215 , A61F2/2409 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/90 , A61F2002/9534 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0078 , A61F2230/008 , A61F2250/001
摘要： The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
摘要翻译： 本发明涉及用于在患者的天然心脏瓣膜内和/或穿过患者的天然心脏瓣膜内血管内递送和释放假体（例如主动脉假体）的装置和方法，以下称为替换患者的心脏瓣膜。 在一些实施例中，递送系统包括多个第一致动元件，其适于以第一构造接合多个第二元件以在输送系统内捕获植入物，并且其中多个第一可致动元件适于接合多个第二可动元件 元件处于第二配置并且从输送系统释放植入物。
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公开(公告)号：US07824442B2
公开(公告)日：2010-11-02
申请号：US10982692
申请日：2004-11-05
申请人： Amr Salahieh , Hans F. Valencia , Brian D. Brandt , Claudio Argento , Ulrich R. Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight P. Morejohn , Tom Saul
发明人： Amr Salahieh , Hans F. Valencia , Brian D. Brandt , Claudio Argento , Ulrich R. Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight P. Morejohn , Tom Saul
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/005 , A61F2220/0058 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a sheath to a vicinity of the heart valve; deploying the anchor from the sheath; expanding the anchor with a deployment tool comprising a plurality of actuation elements to contact tissue at an anchor site; and retrieving the anchor into the sheath. Another aspect of the invention provides apparatus including a sheath; a deployment tool comprising a plurality of anchor actuation elements; a replacement valve configured to be disposed within the sheath for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the sheath for delivery to the vicinity of the heart valve, to be deployed from the sheath, to be expanded by the deployment tool to contact tissue at an anchor site and to be retrieved back into the sheath after having been expanded.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以下步骤：血管内递送替代瓣膜和可膨胀锚固件，所述替换瓣膜和可扩张锚固件处于护套内的未膨胀构型至心脏瓣膜附近; 从护套部署锚; 使用包括多个致动元件的展开工具来扩展锚，以在锚定位置处接触组织; 并将锚固件收回到护套中。 本发明的另一方面提供了一种包括护套的装置; 包括多个锚致动元件的展开工具; 配置成设置在所述护套内用于输送到所述心脏瓣膜附近的置换瓣膜; 以及被构造成设置在所述护套内以用于输送到所述心脏瓣膜附近的可扩张锚，以从所述鞘部署，以由所述展开工具扩张以在锚定位置处接触组织并被回收到所述鞘中 在扩大后。
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公开(公告)号：US08894703B2
公开(公告)日：2014-11-25
申请号：US13166184
申请日：2011-06-22
申请人： Amr Salahieh , Hans F. Valencia , Brian D. Brandt , Claudio Argento , Ulrich R. Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight P. Morejohn , Tom Saul
发明人： Amr Salahieh , Hans F. Valencia , Brian D. Brandt , Claudio Argento , Ulrich R. Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight P. Morejohn , Tom Saul
IPC分类号： A61F2/24 , A61B17/064 , A61F2/90 , A61B17/068 , A61B17/22 , A61B17/221
CPC分类号： A61F2/2427 , A61B17/0644 , A61B17/068 , A61B17/221 , A61B2017/22035 , A61B2017/2215 , A61F2/2409 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/90 , A61F2002/9534 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0078 , A61F2230/008 , A61F2250/001
摘要： The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
摘要翻译： 本发明涉及用于在患者的天然心脏瓣膜内和/或穿过患者的天然心脏瓣膜内血管内递送和释放假体（例如主动脉假体）的装置和方法，以下称为替换患者的心脏瓣膜。 在一些实施例中，递送系统包括多个第一可致动元件，其适于以第一构造接合多个第二元件以在输送系统内捕获植入物，并且其中多个第一可致动元件适于接合多个第二可动元件 元件处于第二配置并且从输送系统释放植入物。
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公开(公告)号：US20050137699A1
公开(公告)日：2005-06-23
申请号：US10982692
申请日：2004-11-05
申请人： Amr Salahieh , Hans Valencia , Brian Brandt , Claudio Argento , Ulrich Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight Morejohn , Tom Saul
发明人： Amr Salahieh , Hans Valencia , Brian Brandt , Claudio Argento , Ulrich Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight Morejohn , Tom Saul
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/005 , A61F2220/0058 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a sheath to a vicinity of the heart valve; deploying the anchor from the sheath; expanding the anchor with a deployment tool comprising a plurality of actuation elements to contact tissue at an anchor site; and retrieving the anchor into the sheath. Another aspect of the invention provides apparatus including a sheath; a deployment tool comprising a plurality of anchor actuation elements; a replacement valve configured to be disposed within the sheath for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the sheath for delivery to the vicinity of the heart valve, to be deployed from the sheath, to be expanded by the deployment tool to contact tissue at an anchor site and to be retrieved back into the sheath after having been expanded.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以下步骤：血管内递送替代瓣膜和可膨胀锚固件，所述替换瓣膜和可扩张锚固件处于护套内的未膨胀构型至心脏瓣膜附近; 从护套部署锚; 使用包括多个致动元件的展开工具来扩展锚，以在锚定位置处接触组织; 并将锚固件收回到护套中。 本发明的另一方面提供了一种包括护套的装置; 包括多个锚致动元件的展开工具; 配置成设置在所述护套内用于输送到所述心脏瓣膜附近的置换瓣膜; 以及被构造成设置在所述护套内以用于输送到所述心脏瓣膜附近的可扩张锚，以从所述鞘部署，以由所述展开工具扩张以在锚定位置处接触组织并被回收到所述鞘中 在扩大后。
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公开(公告)号：US20070203503A1
公开(公告)日：2007-08-30
申请号：US11706549
申请日：2007-02-14
申请人： Amr Salahieh , Hans Valencia , Brian Brandt , Claudio Argento , Ulrich Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight Morejohn , Tom Saul
发明人： Amr Salahieh , Hans Valencia , Brian Brandt , Claudio Argento , Ulrich Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight Morejohn , Tom Saul
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61B17/0644 , A61B17/068 , A61B17/221 , A61B2017/22035 , A61B2017/2215 , A61F2/2409 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/90 , A61F2002/9534 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0078 , A61F2230/008 , A61F2250/001
摘要： The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
摘要翻译： 本发明涉及用于在患者的天然心脏瓣膜内和/或穿过患者的天然心脏瓣膜内血管内递送和释放假体（例如主动脉假体）的装置和方法，以下称为替换患者的心脏瓣膜。 在一些实施例中，递送系统包括多个第一致动元件，其适于以第一构造接合多个第二元件以在输送系统内捕获植入物，并且其中多个第一可致动元件适于接合多个第二可动元件 元件处于第二配置并且从输送系统释放植入物。
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公开(公告)号：US20070010877A1
公开(公告)日：2007-01-11
申请号：US11532019
申请日：2006-09-14
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans Valencia , Daniel Hildebrand , Brian Brandt , Dwight Morejohn , Claudio Argento , Tom Saul , Ulrich Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans Valencia , Daniel Hildebrand , Brian Brandt , Dwight Morejohn , Claudio Argento , Tom Saul , Ulrich Haug
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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