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公开(公告)号:US20070105852A1
公开(公告)日:2007-05-10
申请号:US10596419
申请日:2005-01-05
申请人: Ana Castano Mansanet , Esteban Dominguez-Manzanares , Ana Escribano , Maria Fernandez , William Hornback , Alma Jimenez-Aguado , Eric Tromiczak , Zhipei Wu , Hamideh Zarrinmayeh , Dennis Zimmerman
发明人: Ana Castano Mansanet , Esteban Dominguez-Manzanares , Ana Escribano , Maria Fernandez , William Hornback , Alma Jimenez-Aguado , Eric Tromiczak , Zhipei Wu , Hamideh Zarrinmayeh , Dennis Zimmerman
IPC分类号: A61K31/5377 , A61K31/665 , A61K31/497 , A61K31/506 , A61K31/433 , A61K31/4433 , A61K31/4436 , A61K31/425 , A61K31/453
CPC分类号: C07D307/68 , C07D333/38 , C07D409/10 , C07D417/10
摘要: The present invention relates to thiophene and furan compounds and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression.
摘要翻译: 本发明涉及噻吩和呋喃化合物及其药学上可接受的盐,并且还涉及它们在治疗精神分裂症,与精神分裂症相关的认知缺陷,阿尔茨海默病,阿尔茨海默氏型痴呆,轻度认知障碍或抑郁症中的用途。
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公开(公告)号:US20070173526A1
公开(公告)日:2007-07-26
申请号:US10598473
申请日:2005-03-17
申请人: Michael Bell , Guoqing Cao , Ana Escribano , Maria Fernandez , Peter Lander , Nathan Mantlo , Eva Martin de la Nava , Ana Mateo Herranz , Daniel Mayhugh , Xiaodong Wang
发明人: Michael Bell , Guoqing Cao , Ana Escribano , Maria Fernandez , Peter Lander , Nathan Mantlo , Eva Martin de la Nava , Ana Mateo Herranz , Daniel Mayhugh , Xiaodong Wang
IPC分类号: A61K31/4745 , A61K31/4743 , C07D498/02 , C07D471/02
CPC分类号: C07D495/04 , C07D471/04 , C07D487/04
摘要: The present invention discloses compounds of formula (I) wherein A, n, q, K, W, X, Y; Z, R1, R2, R3, R4, R5, and R6 are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and its sequelae.
摘要翻译: 本发明公开了式(I)的化合物,其中A,n,q,K,W,X,Y; Z,R 1,R 2,R 3,R 4,R 5,..., >和R 6'如本文所定义,并且其药物组合物和使用方法被公开用于治疗血脂异常及其后遗症。
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公开(公告)号:US20070254869A1
公开(公告)日:2007-11-01
申请号:US10574649
申请日:2004-10-07
申请人: Guoqing Cao , Ana Escribano , Maria Fernandez , Todd Fields , Douglas Gernert , Christopher Cioffi , Robert Herr , Nathan Mantlo , Eva Martin De La Nava , Ana Mateo Herranz , Daniel Mayhugh , Xiaodong Wang
发明人: Guoqing Cao , Ana Escribano , Maria Fernandez , Todd Fields , Douglas Gernert , Christopher Cioffi , Robert Herr , Nathan Mantlo , Eva Martin De La Nava , Ana Mateo Herranz , Daniel Mayhugh , Xiaodong Wang
IPC分类号: A61K31/55 , A61P9/10 , C07D223/14 , C07D223/16
CPC分类号: C07D223/16 , C07D223/14 , C07D223/32 , C07D225/06 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D413/04 , C07D491/04
摘要: Compounds of formula I wherein n, m, p, q, y, R1 R2, R3, R4, R5, and R6 are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating artherosclerosis and its sequelae.
摘要翻译: 其中n,m,p,q,y,R 1,R 2,R 3,R 4, R 5,R 5和R 6如本文所定义,并且它们的药物组合物和使用方法被公开用于治疗动脉粥样硬化及其后遗症。
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公开(公告)号:US20070244095A1
公开(公告)日:2007-10-18
申请号:US11570542
申请日:2005-06-23
申请人: Xinchao Chen , Christopher Cioffi , Sean Dinn , Ana Escribano , Maria Fernandez , Todd Fields , Robert Herr , Nathan Mantlo , Eva Martin De La Nava , Ana Mateo-Herranz , Saravanan Parthasarathy , Xiaodong Wang
发明人: Xinchao Chen , Christopher Cioffi , Sean Dinn , Ana Escribano , Maria Fernandez , Todd Fields , Robert Herr , Nathan Mantlo , Eva Martin De La Nava , Ana Mateo-Herranz , Saravanan Parthasarathy , Xiaodong Wang
IPC分类号: A61K31/55 , C07D223/16
CPC分类号: C07D401/14 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/14 , C07D413/12 , C07D417/12 , C07D491/04
摘要: Compounds of formula I wherein n, m, p, q, Y, R1 R2, R3a, R3b, R4, R5, and R6 are as defined herein and their pharmaceutical compositions and methods of use are disclosed.
摘要翻译: 其中n,m,p,q,Y,R 1,R 2,R 3a,R 3b, R 4,R 5,R 5和R 6如本文所定义,并且公开了它们的药物组合物和使用方法。
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公开(公告)号:US20070208003A1
公开(公告)日:2007-09-06
申请号:US10598686
申请日:2005-03-17
申请人: Michael Bell , Guoqing Cao , Ana Escribano , Maria Fernandez , Nathan Mantlo , Eva Martin de la Nava , Ana Mateo Herranz , Daniel Mayhugh , Xiadong Wang
发明人: Michael Bell , Guoqing Cao , Ana Escribano , Maria Fernandez , Nathan Mantlo , Eva Martin de la Nava , Ana Mateo Herranz , Daniel Mayhugh , Xiadong Wang
IPC分类号: A61K31/55 , C07D498/02 , C07D487/02
CPC分类号: C07D495/04 , C07D471/04 , C07D487/04
摘要: The present invention discloses compounds of formula I wherein A, n, m, j, q, y, W, X, Y, Z, R1, R2, R3, R4, R5, and R6 are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and its sequelae.
摘要翻译: 本发明公开了式I的化合物,其中A,n,m,j,q,y,w,X,Y,Z,R 1,R 2,R R 4,R 5,R 5和R 6如本文所定义,并且它们的药物组合物和方法 公开了用于治疗血脂异常及其后遗症的用途。
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公开(公告)号:US20130080480A1
公开(公告)日:2013-03-28
申请号:US13245720
申请日:2011-09-26
申请人: Yun Mao , Maria Fernandez , Changbin Liu , Jacobus Van Der Merwe
发明人: Yun Mao , Maria Fernandez , Changbin Liu , Jacobus Van Der Merwe
IPC分类号: G06F17/30
CPC分类号: H04L41/5009 , G06F17/30194 , H04L67/10
摘要: An aspect of the disclosed technology is a general-purpose platform that may be used to provide resilient cloud services. Tasks may be written as procedures in general-purpose programming languages that directly manipulate resources via control interfaces. In one implementation, resource states, such as router configurations and virtual machine states, associated with a cloud customer that provides communications services, may be abstracted into tables in a relational or semi-structured database. State changes that have been written to the database tables are automatically propagated by the database to appropriate customer physical devices, such as network elements, thereby implementing various customer network operations.
摘要翻译: 所公开技术的一个方面是可用于提供弹性云服务的通用平台。 任务可以写成通用控制界面直接操纵资源的通用编程语言中的程序。 在一个实现中,与提供通信服务的云客户相关联的资源状态(例如路由器配置和虚拟机状态)可以被抽象为关系或半结构化数据库中的表。 已写入数据库表的状态更改会自动由数据库传播到适当的客户物理设备(如网络元素),从而实现各种客户网络操作。
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公开(公告)号:US09106584B2
公开(公告)日:2015-08-11
申请号:US13245720
申请日:2011-09-26
申请人: Yun Mao , Maria Fernandez , Changbin Liu , Jacobus Van Der Merwe
发明人: Yun Mao , Maria Fernandez , Changbin Liu , Jacobus Van Der Merwe
CPC分类号: H04L41/5009 , G06F17/30194 , H04L67/10
摘要: An aspect of the disclosed technology is a general-purpose platform that may be used to provide resilient cloud services. Tasks may be written as procedures in general-purpose programming languages that directly manipulate resources via control interfaces. In one implementation, resource states, such as router configurations and virtual machine states, associated with a cloud customer that provides communications services, may be abstracted into tables in a relational or semi-structured database. State changes that have been written to the database tables are automatically propagated by the database to appropriate customer physical devices, such as network elements, thereby implementing various customer network operations.
摘要翻译: 所公开技术的一个方面是可用于提供弹性云服务的通用平台。 任务可以写成通用控制界面直接操纵资源的通用编程语言中的程序。 在一个实现中,与提供通信服务的云客户相关联的资源状态(例如路由器配置和虚拟机状态)可以被抽象为关系或半结构化数据库中的表。 已写入数据库表的状态更改会自动由数据库传播到适当的客户物理设备(如网络元素),从而实现各种客户网络操作。
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