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17 条记录 (耗时 0.027 秒)

    Objective Model Of Apparent Age, Methods And Use
    4.
    发明申请
    Objective Model Of Apparent Age, Methods And Use 有权
    表观年龄，方法和使用的目标模型

    公开(公告)号：US20110202480A1

    公开(公告)日：2011-08-18

    申请号：US13060450

    申请日：2009-09-04

    申请人： Daniel H. Maes ,  Rose Marie Sparacio ,  Denise M. Dicanio ,  Neelam Muizzuddin ,  Lieve Declerq

    发明人： Daniel H. Maes ,  Rose Marie Sparacio ,  Denise M. Dicanio ,  Neelam Muizzuddin ,  Lieve Declerq

    IPC分类号： G06F17/00 ,  G06F17/10 ,  G06F19/00 ,  G06Q90/00

    CPC分类号： G06Q99/00 ,  A61B5/441 ,  A61B8/0858 ,  G06F19/00 ,  G16H10/20 ,  G16H50/50

    摘要： Methods of developing equations for objectively assigning or predicting an apparent age are disclosed. Advantageously, the equations of objective apparent age may be based on a relatively small number of critical parameters combined in a way that accounts for all or most of the apparent skin aging in a defined population or sub-population. Despite the relatively small data collection requirements, the present invention includes an objective model of apparent age that is useful for evaluation of products, useful for predicting treatment outcomes and useful for predicting the effects of deteriorative factors. The formalization of an Objective Apparent Age Score allows one to identify the biophysical and biochemical parameters that mostly influence an individual's apparent age, and can be used to select specific anti-aging treatments with increased chances of visible success. The Objective Apparent Age Score may also be used to support marketing claims.

    摘要翻译： 公开了客观分配或预测表观年龄的方程的方法。 有利地，客观表观年龄的方程可以基于相对较少数量的关键参数，其组合方式考虑了定义的群体或子群体中的所有或大部分明显的皮肤老化。 尽管数据收集要求相对较小，但是本发明包括可用于评估产品的明显年龄的客观模型，对预测治疗结果有用，并且可用于预测恶化因素的影响。 客观表观年龄分数的形式化允许人们识别主要影响个体表观年龄的生物物理和生物化学参数，并且可以用于选择具有可见成功机会的特定抗衰老治疗。 客观表观年龄分数也可用于支持营销声明。

    Extracts from black yeast for whitening skin
    5.
    发明授权
    Extracts from black yeast for whitening skin 有权
    从黑色酵母提取物美白皮肤

    公开(公告)号：US07862822B2

    公开(公告)日：2011-01-04

    申请号：US11860909

    申请日：2007-09-25

    申请人： Thomas Mammone ,  Neelam Muizzuddin ,  Steven F. Schnittger

    发明人： Thomas Mammone ,  Neelam Muizzuddin ,  Steven F. Schnittger

    IPC分类号： A61K36/06

    CPC分类号： A61K8/99 ,  A61Q19/02

    摘要： The present invention relates to topical skin whitening compositions comprising a whitening effective amount of a black yeast-derived melanin-degrading enzyme extract and a method of preparing the compositions. The compositions provide a whitening effect by degrading melanin on the surface of the skin, the hair and the nails. The enzyme extract can be derived from Exophiala mansonii. The compositions containing the enzyme extract are more effective than are similar compositions containing kojic acid in producing a whitening effect on the skin.

    摘要翻译： 本发明涉及包含增白有效量的黑酵母衍生的黑色素降解酶提取物的局部皮肤增白组合物和制备该组合物的方法。 该组合物通过降解皮肤表面，头发和指甲上的黑色素来提供美白效果。 酶提取物可以衍生自洋葱（Exophiala mansonii）。 含有酶提取物的组合物比含有曲酸的类似组合物在皮肤上产生美白效果方面更有效。

    Anti-irritant compositions containing a cyclic nucleotide
    6.
    发明授权
    Anti-irritant compositions containing a cyclic nucleotide 有权
    含有环状核苷酸的抗刺激性组合物

    公开(公告)号：US06531140B2

    公开(公告)日：2003-03-11

    申请号：US09304562

    申请日：1999-05-04

    申请人： Thomas Mammone ,  Earl C. Goyarts ,  Neelam Muizzuddin

    发明人： Thomas Mammone ,  Earl C. Goyarts ,  Neelam Muizzuddin

    IPC分类号： A61K600

    CPC分类号： A61K31/7076 ,  A61K8/606 ,  A61K31/708 ,  A61K2800/75 ,  A61K2800/782 ,  A61Q19/00

    摘要： The present invention relates to cosmetic or pharmaceutical topical compositions containing at least one cyclic nucleotide having its 2′ hydroxyl group replaced by a hydrogen atom for inhibiting phosphodiesterase activity. The phosphodiesterase inhibitor is in combination with a magnesium buffer and a cosmetically or pharmaceutically acceptable carrier. The invention also includes methods for treating or preventing inflammation or irritation such as is common in the skin disease, atopic dermatitis, which is known to be related to the uncontrolled activity of phosphodiesterase.

    摘要翻译： 本发明涉及含有至少一个环状核苷酸的化妆品或药物局部组合物，其具有被氢原子取代的2'羟基以抑制磷酸二酯酶活性。 磷酸二酯酶抑制剂与镁缓冲剂和化妆品或药学上可接受的载体组合。 本发明还包括治疗或预防炎症或刺激的方法，例如已知与磷酸二酯酶的不受控制的活性相关的皮肤病，特应性皮炎中常见的方法。

    Extracts from black yeast for whitening skin
    9.
    发明申请
    Extracts from black yeast for whitening skin 有权
    从黑色酵母提取物美白皮肤

    公开(公告)号：US20070154444A1

    公开(公告)日：2007-07-05

    申请号：US11322014

    申请日：2005-12-29

    申请人： Thomas Mammone ,  Neelam Muizzuddin ,  Steven Schnittger

    发明人： Thomas Mammone ,  Neelam Muizzuddin ,  Steven Schnittger

    IPC分类号： A61K8/97 ,  A61K36/06

    CPC分类号： A61K36/06 ,  A61K8/66 ,  A61K8/99 ,  A61Q19/02

    摘要： The present invention relates to topical skin whitening compositions comprising a whitening effective amount of a black yeast-derived melanin-degrading enzyme extract and a method of preparing the compositions. The compositions provide a whitening effect by degrading melanin on the surface of the skin, the hair and the nails. The enzyme extract can be derived from Exophiala mansonii. The compositions containing the enzyme extract are more effective than are similar compositions containing kojic acid in producing a whitening effect on the skin.

    摘要翻译： 本发明涉及包含增白有效量的黑酵母衍生的黑色素降解酶提取物的局部皮肤增白组合物和制备该组合物的方法。 该组合物通过降解皮肤表面，头发和指甲上的黑色素来提供美白效果。 酶提取物可以衍生自洋葱（Exophiala mansonii）。 含有酶提取物的组合物比含有曲酸的类似组合物在皮肤上产生美白效果方面更有效。